CL2018000559A1 - Methods and compositions for treating conditions associated with abnormal inflammatory responses - Google Patents

Methods and compositions for treating conditions associated with abnormal inflammatory responses

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Publication number
CL2018000559A1
CL2018000559A1 CL2018000559A CL2018000559A CL2018000559A1 CL 2018000559 A1 CL2018000559 A1 CL 2018000559A1 CL 2018000559 A CL2018000559 A CL 2018000559A CL 2018000559 A CL2018000559 A CL 2018000559A CL 2018000559 A1 CL2018000559 A1 CL 2018000559A1
Authority
CL
Chile
Prior art keywords
compositions
methods
hydrate
crystals
pharmaceutically acceptable
Prior art date
Application number
CL2018000559A
Other languages
Spanish (es)
Inventor
Gary Glick
Luigi Franchi
Original Assignee
First Wave Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Wave Bio Inc filed Critical First Wave Bio Inc
Publication of CL2018000559A1 publication Critical patent/CL2018000559A1/en

Links

Abstract

Las entidades químicas características de la revelación (por ejemplo, un compuesto que presenta actividad como agente mitocondrial desacoplante o una sal farmacéuticamente aceptable y/o hidrato y/o cocristales de los mismos; por ejemplo, un compuesto, tal como la niclosamida o una sal farmacéuticamente aceptable y/o hidrato y/o cocristales de los mismos; por ejemplo, un compuesto, tal como un análogo a la niclosamida, o una sal farmacéuticamente aceptable y/o hidrato y/o cocristales de los mismos) que son útiles, por ejemplo, para el tratamiento de uno o más síntomas asociados a una patología que se caracteriza por una respuesta inflamatoria anormal (por ejemplo, enfermedades inflamatorias de los intestinos) en un sujeto (por ejemplo, un humano). La revelación también presenta tanto composiciones, como también otros métodos de uso y aplicación de las mismas. The chemical entities characteristic of the disclosure (for example, a compound exhibiting activity as a decoupling mitochondrial agent or a pharmaceutically acceptable salt and / or hydrate and / or co-crystals thereof; for example, a compound, such as niclosamide or a salt pharmaceutically acceptable and / or hydrate and / or co-crystals thereof; for example, a compound, such as a niclosamide analogue, or a pharmaceutically acceptable salt and / or hydrate and / or co-crystals thereof) which are useful, for for example, for the treatment of one or more symptoms associated with a pathology characterized by an abnormal inflammatory response (for example, inflammatory diseases of the intestines) in a subject (for example, a human). The disclosure also presents both compositions, as well as other methods of use and application thereof.

CL2018000559A 2015-10-14 2018-03-01 Methods and compositions for treating conditions associated with abnormal inflammatory responses CL2018000559A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562241508P 2015-10-14 2015-10-14
US201662213016P 2016-09-01 2016-09-01

Publications (1)

Publication Number Publication Date
CL2018000559A1 true CL2018000559A1 (en) 2018-08-17

Family

ID=65563022

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018000559A CL2018000559A1 (en) 2015-10-14 2018-03-01 Methods and compositions for treating conditions associated with abnormal inflammatory responses

Country Status (1)

Country Link
CL (1) CL2018000559A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11452692B2 (en) 2018-09-28 2022-09-27 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11452692B2 (en) 2018-09-28 2022-09-27 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation
US11471413B2 (en) 2018-09-28 2022-10-18 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation
US11890378B2 (en) 2018-09-28 2024-02-06 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation

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