CL2016000753A1 - Attenuation of neurodegeneration associated with parkison's disease by inhibiting the dopamine d3 receptor in t cd4 + cells. - Google Patents
Attenuation of neurodegeneration associated with parkison's disease by inhibiting the dopamine d3 receptor in t cd4 + cells.Info
- Publication number
- CL2016000753A1 CL2016000753A1 CL2016000753A CL2016000753A CL2016000753A1 CL 2016000753 A1 CL2016000753 A1 CL 2016000753A1 CL 2016000753 A CL2016000753 A CL 2016000753A CL 2016000753 A CL2016000753 A CL 2016000753A CL 2016000753 A1 CL2016000753 A1 CL 2016000753A1
- Authority
- CL
- Chile
- Prior art keywords
- parkison
- dopamine
- attenuation
- receptor
- inhibiting
- Prior art date
Links
- 102000004073 Dopamine D3 Receptors Human genes 0.000 title 1
- 108090000525 Dopamine D3 Receptors Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46432—Nervous system antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464401—Neoantigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/80—Neurotransmitters; Neurohormones
- C12N2501/815—Dopamine
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CL2016000753A CL2016000753A1 (en) | 2016-03-31 | 2016-03-31 | Attenuation of neurodegeneration associated with parkison's disease by inhibiting the dopamine d3 receptor in t cd4 + cells. |
PCT/IB2017/051868 WO2017168390A2 (en) | 2016-03-31 | 2017-03-31 | Attenuation of neurodegeneration associated with parkinson's disease by inhibition of the dopamine d3 receptor in cd4+ t cells |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CL2016000753A CL2016000753A1 (en) | 2016-03-31 | 2016-03-31 | Attenuation of neurodegeneration associated with parkison's disease by inhibiting the dopamine d3 receptor in t cd4 + cells. |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016000753A1 true CL2016000753A1 (en) | 2017-11-10 |
Family
ID=59963679
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2016000753A CL2016000753A1 (en) | 2016-03-31 | 2016-03-31 | Attenuation of neurodegeneration associated with parkison's disease by inhibiting the dopamine d3 receptor in t cd4 + cells. |
Country Status (2)
Country | Link |
---|---|
CL (1) | CL2016000753A1 (en) |
WO (1) | WO2017168390A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021016474A1 (en) * | 2019-07-23 | 2021-01-28 | Fundación Ciencia Para La Vida (Fcv) | Ibd therapy by inhibition of drd3 in regulatory t cells |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2343679A (en) * | 1998-11-16 | 2000-05-17 | Alison Miriam Davies | Autologous transplantation and method for making cells dormant |
AU2002347573A1 (en) * | 2001-10-29 | 2003-05-12 | Yeda Research And Development Co. Ltd. | Methods and pharmaceutical compositions for dopaminergic modulation of t-cell adhesion and acitivty |
AU2003267201B2 (en) * | 2002-09-14 | 2009-04-23 | The Gov't Of The U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services | Structurally rigid dopamine D3 receptor selective ligands and process for making them |
-
2016
- 2016-03-31 CL CL2016000753A patent/CL2016000753A1/en unknown
-
2017
- 2017-03-31 WO PCT/IB2017/051868 patent/WO2017168390A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2017168390A3 (en) | 2017-11-16 |
WO2017168390A2 (en) | 2017-10-05 |
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