CL2015000375A1 - Pharmaceutical composition in the form of microparticles comprising an inert core and at least a first layer of active ingredient; microparticle formation process; pharmaceutical combination; pharmaceutical kit; use to treat and / or prevent edema, cardiovascular diseases, diabetes, hypertension, among others. - Google Patents

Pharmaceutical composition in the form of microparticles comprising an inert core and at least a first layer of active ingredient; microparticle formation process; pharmaceutical combination; pharmaceutical kit; use to treat and / or prevent edema, cardiovascular diseases, diabetes, hypertension, among others.

Info

Publication number
CL2015000375A1
CL2015000375A1 CL2015000375A CL2015000375A CL2015000375A1 CL 2015000375 A1 CL2015000375 A1 CL 2015000375A1 CL 2015000375 A CL2015000375 A CL 2015000375A CL 2015000375 A CL2015000375 A CL 2015000375A CL 2015000375 A1 CL2015000375 A1 CL 2015000375A1
Authority
CL
Chile
Prior art keywords
pharmaceutical
microparticles
hypertension
diabetes
treat
Prior art date
Application number
CL2015000375A
Other languages
Spanish (es)
Inventor
Hernández Gustavo Barranco
Guiza Maria Del Coral Luna
Arroyo Héctor Senosiain
Original Assignee
Senosiain S A De C V Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50435594&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015000375(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senosiain S A De C V Lab filed Critical Senosiain S A De C V Lab
Publication of CL2015000375A1 publication Critical patent/CL2015000375A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
CL2015000375A 2012-08-17 2015-02-17 Pharmaceutical composition in the form of microparticles comprising an inert core and at least a first layer of active ingredient; microparticle formation process; pharmaceutical combination; pharmaceutical kit; use to treat and / or prevent edema, cardiovascular diseases, diabetes, hypertension, among others. CL2015000375A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2012009583A MX351059B (en) 2012-08-17 2012-08-17 Oral pharmaceutical composition in the form of microspheres and preparation method.

Publications (1)

Publication Number Publication Date
CL2015000375A1 true CL2015000375A1 (en) 2015-07-10

Family

ID=50435594

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000375A CL2015000375A1 (en) 2012-08-17 2015-02-17 Pharmaceutical composition in the form of microparticles comprising an inert core and at least a first layer of active ingredient; microparticle formation process; pharmaceutical combination; pharmaceutical kit; use to treat and / or prevent edema, cardiovascular diseases, diabetes, hypertension, among others.

Country Status (8)

Country Link
CL (1) CL2015000375A1 (en)
CO (1) CO7310526A2 (en)
CR (1) CR20150077A (en)
DO (1) DOP2015000028A (en)
GT (1) GT201500035A (en)
MX (1) MX351059B (en)
PE (1) PE20150710A1 (en)
WO (1) WO2014027334A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2707533C2 (en) 2013-03-27 2019-11-27 Ф. Хоффманн-Ля Рош Аг Genetic markers for prediction of susceptibility to therapy
WO2016016157A1 (en) 2014-07-30 2016-02-04 F. Hoffmann-La Roche Ag Genetic markers for predicting responsiveness to therapy with hdl-raising or hdl mimicking agent
CN104523710B (en) * 2014-12-30 2018-05-25 石药集团欧意药业有限公司 A kind of bisulfate clopidogrel aspirin Composite Double synusia and preparation method thereof
KR101710441B1 (en) * 2015-12-28 2017-02-28 신풍제약주식회사 Tablet with improved stability and dissolution
WO2018150286A1 (en) 2017-02-17 2018-08-23 Unichem Laboratories Ltd Pharmaceutical composition of apixaban
CN106821996A (en) * 2017-03-01 2017-06-13 华益药业科技(安徽)有限公司 Enalapril maleate granule and preparation method thereof
AU2019255599B2 (en) * 2018-04-16 2024-02-29 Bristol-Myers Squibb Holdings Ireland Unlimited Company Apixaban formulations
US20210290543A1 (en) * 2020-02-19 2021-09-23 Nano Pharmasolutions, Inc. Therapeutic agent nanoparticles and methods of preparation
US11833133B2 (en) * 2020-08-13 2023-12-05 Orient Pharma Co., Ltd. Solid oral pharmaceutical composition
CN113413364A (en) * 2021-05-31 2021-09-21 辰欣药业股份有限公司 Enoxaparin sodium injection and preparation method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100226990A1 (en) * 2006-01-27 2010-09-09 The Provost, Fellows And Scholars Of The College O Method of Producing Porous Microparticles
MXPA06010972A (en) * 2006-09-25 2009-04-17 World Trade Imp Export Wtie Ag Process for stabilizing famotidine.
WO2008045006A1 (en) * 2006-10-11 2008-04-17 Fako Ilaclari A. S. Formulations of candesartan
MX2007008440A (en) * 2007-07-11 2009-02-18 Senosiain S A De C V Lab Combined pharmaceutical composition.

Also Published As

Publication number Publication date
WO2014027334A2 (en) 2014-02-20
GT201500035A (en) 2017-10-24
MX351059B (en) 2017-09-29
PE20150710A1 (en) 2015-05-28
MX2012009583A (en) 2014-02-26
CO7310526A2 (en) 2015-06-30
DOP2015000028A (en) 2015-03-15
CR20150077A (en) 2015-05-13
WO2014027334A3 (en) 2014-04-10

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