CL2013003728A1 - Antagonist antibody or fragment thereof that binds to human ox40; epitope of the human ox40 extracellular domain that is bound by the aforementioned antibody; nucleic acid encoding the antibody; vector and host cell comprising said nucleic acid; method to produce the antibody; composition comprising the antibody; immunoconjugate; use to treat disorders mediated by ox40. - Google Patents

Antagonist antibody or fragment thereof that binds to human ox40; epitope of the human ox40 extracellular domain that is bound by the aforementioned antibody; nucleic acid encoding the antibody; vector and host cell comprising said nucleic acid; method to produce the antibody; composition comprising the antibody; immunoconjugate; use to treat disorders mediated by ox40.

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Publication number
CL2013003728A1
CL2013003728A1 CL2013003728A CL2013003728A CL2013003728A1 CL 2013003728 A1 CL2013003728 A1 CL 2013003728A1 CL 2013003728 A CL2013003728 A CL 2013003728A CL 2013003728 A CL2013003728 A CL 2013003728A CL 2013003728 A1 CL2013003728 A1 CL 2013003728A1
Authority
CL
Chile
Prior art keywords
antibody
human
nucleic acid
epitope
fragment
Prior art date
Application number
CL2013003728A
Other languages
Spanish (es)
Inventor
Antoine Attinger
Stanislas Blein
Jonathan Albert Back
Samuel Hou
Rami Lissilaa
Original Assignee
Glenmark Pharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46601863&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013003728(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glenmark Pharmaceuticals Sa filed Critical Glenmark Pharmaceuticals Sa
Publication of CL2013003728A1 publication Critical patent/CL2013003728A1/en

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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Abstract

LA INVENCIÓN PROPORCIONA A UN ANTICUERPO ANTAGONISTA O FRAGMENTO DEL MISMO QUE SE UNE A OX40 DE HUMANO; EPITOPE DEL DOMINIO EXTRACELULAR DE OX40 DE HUMANO QUE ES UNIDO POR EN ANTICUERPO ANTES MENCIONADO; ACIDO NUCLEICO QUE CODIFICA EL ANTICUERPO; VECTOR Y CÉLULA HOSPEDERA QUE COMPRENDEN DICHO ACIDO NUCLEICO; METODO PARA PRODUCIR EL ANTICUERPO; COMPOSICION QUE COMPRENDE EL ANTICUERPO; INMUNOCONJUGADO; USO PARA TRATAR TRASTORNOS MEDIADOS POR OX40.THE INVENTION PROVIDES AN ANTAGONIST ANTIBODY OR FRAGMENT OF THE SAME THAT JOINS OX40 OF HUMAN; EPITOPE OF THE EXTRACELLULAR DOMAIN OF OX40 OF HUMAN THAT IS UNITED BY IN ANTIBODY BEFORE MENTIONED; NUCLEIC ACID CODING THE ANTIBODY; VECTOR AND HOSPEDERA CELL THAT UNDERSTAND SUCH NUCLEIC ACID; METHOD TO PRODUCE THE ANTIBODY; COMPOSITION THAT THE ANTIBODY UNDERSTANDS; IMMUNOCONJUGADO; USE TO TREAT OX40 DISORDERS.

CL2013003728A 2011-07-11 2013-12-26 Antagonist antibody or fragment thereof that binds to human ox40; epitope of the human ox40 extracellular domain that is bound by the aforementioned antibody; nucleic acid encoding the antibody; vector and host cell comprising said nucleic acid; method to produce the antibody; composition comprising the antibody; immunoconjugate; use to treat disorders mediated by ox40. CL2013003728A1 (en)

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