CL2013000656A1 -
Compounds derived from substituted imidazopyridazines; method for preparing a compound; intermediary compounds; pharmaceutical composition; pharmaceutical combination; and use for the prophylaxis or treatment of cancer, leukemia, myelodysplastic syndrome, malignant lymphomas, brain tumors, metatasis.
- Google Patents
Compounds derived from substituted imidazopyridazines; method for preparing a compound; intermediary compounds; pharmaceutical composition; pharmaceutical combination; and use for the prophylaxis or treatment of cancer, leukemia, myelodysplastic syndrome, malignant lymphomas, brain tumors, metatasis.
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Application filed by Bayer Ip GmbhfiledCriticalBayer Ip Gmbh
Publication of CL2013000656A1publicationCriticalpatent/CL2013000656A1/en
CL2013000656A2010-09-102013-03-08
Compounds derived from substituted imidazopyridazines; method for preparing a compound; intermediary compounds; pharmaceutical composition; pharmaceutical combination; and use for the prophylaxis or treatment of cancer, leukemia, myelodysplastic syndrome, malignant lymphomas, brain tumors, metatasis.
CL2013000656A1
(en)
Compounds derived from substituted imidazopyridazines; method for preparing a compound; intermediary compounds; pharmaceutical composition; pharmaceutical combination; and use for the prophylaxis or treatment of cancer, leukemia, myelodysplastic syndrome, malignant lymphomas, brain tumors, metatasis.
Compounds derived from nitrogen heterocycles, kinase modulators; Preparation method; intermediary compound; pharmaceutical composition; and a method to treat a subject who has a disease or condition such as cancer, aml, gastrointestinal stromal tumors or mastocytosis.
Compounds derived from fused aryl and heteroaryl lactams, modulators of ezh2; pharmaceutical composition that includes them; use of the compound for the treatment of cancer.
Compounds derived from substituted morpholin pyrimidines, protein kinase atr inhibitors; Pharmaceutical composition, useful for the prevention or treatment of cancer tumors.
Compounds derived from amino substituted imidazopyridazines, kinase inhibitors, mknk2; Preparation method; intermediary compounds and their use; pharmaceutical composition; pharmaceutical combination; and its use for the treatment of cancer.
Compounds derived from substituted pyrimidine pyridines, serine / threonine kinase inhibitors; preparation procedure; intermediary compounds; pharmaceutical composition; pharmaceutical combination; use for the treatment of a hyperproliferative disease such as melanoma, cancer, leukemia and an inflammatory disease such as arthritis and rheumatism among others.
Compounds derived from (1,8) 2,4 diaryl naphthyridines substituted kinase inhibitors; its procedure for obtaining; pharmaceutical composition; and its use for the treatment and / or prevention of cancer, tumor, malignant tumors, among others; Pharmaceutical kit
Compounds derived from 2-oxo-piperidine and 1,1-dioxide-thiazine, mdm2 inhibitors; pharmaceutical composition that includes them; and its use for the treatment of cancer.
Compounds derived from substituted purine, mtor inhibitors; pharmaceutical composition; pharmaceutical combination; use for the treatment or prevention of cancer, a neurodegenerative disorder or an ophthalmological disease.
Compounds derived from substituted triazolopyridines; Preparation method; intermediary compounds; pharmaceutical composition that includes them; use of the compound for the prophylaxis or treatment of leukemia, malignant lymphomas, head and neck tumors, thorax tumors, gastrointestinal tumors, among others.
Use of compounds derived from pyridin-4-yl-benzene-1,4-diamino substituted by alindole to prepare a medicament for the treatment of a proliferative disorder such as cancer.
Thiazole derived compounds, protein kinase inhibitors; pharmaceutical composition; and use for the treatment of cancer, such as bladder, breast, and kidney cancer.