CL2012002360A1 - Method for preparing a liposomal formulation comprising dissolving a lipid fraction (phospholipids, sterol and a bioactive substance) in an organic solvent, putting together with a removed carrier and introducing a supercritical fluid, discharging the fluid by compression and hydrating; and apparatus for carrying out the method. - Google Patents
Method for preparing a liposomal formulation comprising dissolving a lipid fraction (phospholipids, sterol and a bioactive substance) in an organic solvent, putting together with a removed carrier and introducing a supercritical fluid, discharging the fluid by compression and hydrating; and apparatus for carrying out the method.Info
- Publication number
- CL2012002360A1 CL2012002360A1 CL2012002360A CL2012002360A CL2012002360A1 CL 2012002360 A1 CL2012002360 A1 CL 2012002360A1 CL 2012002360 A CL2012002360 A CL 2012002360A CL 2012002360 A CL2012002360 A CL 2012002360A CL 2012002360 A1 CL2012002360 A1 CL 2012002360A1
- Authority
- CL
- Chile
- Prior art keywords
- fluid
- hydrating
- sterol
- phospholipids
- dissolving
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020100016555A KR101102834B1 (en) | 2010-02-24 | 2010-02-24 | New methods and apparatus for preparing liposomes |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2012002360A1 true CL2012002360A1 (en) | 2013-08-16 |
Family
ID=44507447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2012002360A CL2012002360A1 (en) | 2010-02-24 | 2012-08-24 | Method for preparing a liposomal formulation comprising dissolving a lipid fraction (phospholipids, sterol and a bioactive substance) in an organic solvent, putting together with a removed carrier and introducing a supercritical fluid, discharging the fluid by compression and hydrating; and apparatus for carrying out the method. |
Country Status (9)
Country | Link |
---|---|
US (1) | US9579261B2 (en) |
EP (1) | EP2538921B1 (en) |
JP (1) | JP5787905B2 (en) |
KR (1) | KR101102834B1 (en) |
CN (1) | CN102781428B (en) |
BR (1) | BR112012021703A2 (en) |
CA (1) | CA2789320C (en) |
CL (1) | CL2012002360A1 (en) |
WO (1) | WO2011105835A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU24121B1 (en) | 2012-08-02 | 2015-08-27 | Ct De Ingeniería Genética Y Biotecnología | VESICLES THAT INCLUDE EPIDERMAL GROWTH FACTOR AND COMPOSITIONS CONTAINING THEM |
CN103143033B (en) * | 2013-03-24 | 2014-06-25 | 山西医科大学 | Targeting liver cell carrier and preparation method thereof |
CN105012152B (en) * | 2014-04-23 | 2018-01-02 | 胡权 | The preparation facilities and preparation method of a kind of liposome |
US10342747B2 (en) * | 2015-12-16 | 2019-07-09 | PPP&C Inc. | Apparatus and method for preparing cosmeceutical ingredients containing epi-dermal delivery mechanisms |
CN106581695A (en) * | 2016-10-27 | 2017-04-26 | 山东省分析测试中心 | Cationic liposome, preparation method and applications thereof |
CN110545821A (en) * | 2017-02-21 | 2019-12-06 | Ico治疗公司 | Solid oral formulations of amphotericin B |
EP3651733A4 (en) * | 2017-07-10 | 2021-04-07 | ImmunoVaccine Technologies Inc. | Pharmaceutical compositions, methods for preparation using lipid vesicle particles of defined size, and uses thereof |
CN109432008A (en) * | 2018-12-07 | 2019-03-08 | 河南工业大学 | A kind of preparation method of nano liposomes |
WO2023122495A1 (en) * | 2021-12-22 | 2023-06-29 | Research Triangle Institute | Supercritical ethylene extraction process for selectively recovering phenolic compounds from bio-crude and/or bio-oil |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4766046A (en) | 1985-09-27 | 1988-08-23 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
US5554382A (en) * | 1993-05-28 | 1996-09-10 | Aphios Corporation | Methods and apparatus for making liposomes |
DE60036861T2 (en) * | 1999-03-02 | 2008-07-24 | Transave, Inc. | Encapsulation of biologically active complexes in liposomes |
FR2797398B1 (en) * | 1999-08-11 | 2002-10-18 | Mainelab | MICROPARTICLES FOR PULMONARY ADMINISTRATION |
CA2455597A1 (en) * | 2001-08-03 | 2003-02-13 | National Research Council Of Canada | Liposomes prepared from the extractable lipids from a mycobacterium |
JP2005511521A (en) * | 2001-10-10 | 2005-04-28 | ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド | Powder processing with pressurized gaseous fluid |
CN100471490C (en) * | 2002-08-01 | 2009-03-25 | 谢恬 | Sesquiterpene ketone injection, preparing method and use thereof |
JP2005162702A (en) * | 2003-12-04 | 2005-06-23 | Konica Minolta Medical & Graphic Inc | Method for producing liposome preparation, liposome preparation and apparatus for producing the same |
FR2874836B1 (en) * | 2004-09-09 | 2007-04-27 | Pierre Fabre Medicament Sa | PROCESS FOR COATING POWDERS |
EP1795184A1 (en) * | 2005-12-09 | 2007-06-13 | Ludwig-Maximilians-Universität München | Preparation of powders containing colloidal particles |
-
2010
- 2010-02-24 KR KR1020100016555A patent/KR101102834B1/en active IP Right Grant
-
2011
- 2011-02-24 WO PCT/KR2011/001303 patent/WO2011105835A2/en active Application Filing
- 2011-02-24 CN CN201180011038.3A patent/CN102781428B/en active Active
- 2011-02-24 BR BR112012021703A patent/BR112012021703A2/en not_active Application Discontinuation
- 2011-02-24 CA CA2789320A patent/CA2789320C/en active Active
- 2011-02-24 JP JP2012554934A patent/JP5787905B2/en active Active
- 2011-02-24 EP EP11747725.7A patent/EP2538921B1/en active Active
- 2011-02-24 US US13/580,236 patent/US9579261B2/en active Active
-
2012
- 2012-08-24 CL CL2012002360A patent/CL2012002360A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2789320C (en) | 2015-06-02 |
WO2011105835A3 (en) | 2012-01-12 |
US9579261B2 (en) | 2017-02-28 |
CA2789320A1 (en) | 2011-09-01 |
EP2538921A2 (en) | 2013-01-02 |
CN102781428B (en) | 2017-09-19 |
EP2538921A4 (en) | 2014-05-28 |
WO2011105835A2 (en) | 2011-09-01 |
CN102781428A (en) | 2012-11-14 |
JP5787905B2 (en) | 2015-09-30 |
KR20110096962A (en) | 2011-08-31 |
US20130069261A1 (en) | 2013-03-21 |
EP2538921B1 (en) | 2017-04-26 |
BR112012021703A2 (en) | 2019-09-24 |
JP2013520492A (en) | 2013-06-06 |
KR101102834B1 (en) | 2012-01-05 |
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