CL2011001209A1 - Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis. - Google Patents

Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis.

Info

Publication number
CL2011001209A1
CL2011001209A1 CL2011001209A CL2011001209A CL2011001209A1 CL 2011001209 A1 CL2011001209 A1 CL 2011001209A1 CL 2011001209 A CL2011001209 A CL 2011001209A CL 2011001209 A CL2011001209 A CL 2011001209A CL 2011001209 A1 CL2011001209 A1 CL 2011001209A1
Authority
CL
Chile
Prior art keywords
tumor
capsule
vitro
expression
invade
Prior art date
Application number
CL2011001209A
Other languages
Spanish (es)
Inventor
Diaz Hernan Gonzalez
Parra Alexis Kalergis
Original Assignee
Univ Pontificia Catolica Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pontificia Catolica Chile filed Critical Univ Pontificia Catolica Chile
Priority to CL2011001209A priority Critical patent/CL2011001209A1/en
Publication of CL2011001209A1 publication Critical patent/CL2011001209A1/en
Priority to PCT/IB2012/052572 priority patent/WO2012160519A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

MÉTODO <em>IN VITRO </em>PARA DETERMINAR PRONÓSTICO DE UN CÁNCER PAPILAR DE TIROIDES, QUE COMPRENDE CUANHIFLCAR, EN UNA MUESTRA DE TEJIDO TUMORAL DE UN PACIENTE, LA EXPRESIÓN DE¡ RECEPTOR DE QUIMIOKINA CCR3 Y DONDE LA SOBREEXPRESIÓN DE CCR3 RESPECTO DE UN VALOR DE REFERENCIA INDICA QUE EL TUMOR TIENE ALTAS PROBABILIDADES DE INVAOIR LA CÁPSULA Y GENERAR METÁSTASIS.METHOD <em> IN VITRO </em> TO DETERMINE FORECAST OF A PAPILAR CANCER OF THYROID, WHICH UNDERSTANDS WHEN, IN A TUMOR FABRIC SAMPLE OF A PATIENT, THE EXPRESSION OF CHRIOKINA CCR3 RECEPTOR AND WHERE THE SOCIETY OF THE CCRBREE REPRESENTS A VALUE OF REFERENCE INDICATES THAT THE TUMOR HAS HIGH CHANCES OF INVOLVING THE CAPSULE AND GENERATING METALLASIS.

CL2011001209A 2011-05-24 2011-05-24 Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis. CL2011001209A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CL2011001209A CL2011001209A1 (en) 2011-05-24 2011-05-24 Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis.
PCT/IB2012/052572 WO2012160519A2 (en) 2011-05-24 2012-05-23 Diagnostic method for determining the aggressive and prognosis of papillary thyroid cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2011001209A CL2011001209A1 (en) 2011-05-24 2011-05-24 Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis.

Publications (1)

Publication Number Publication Date
CL2011001209A1 true CL2011001209A1 (en) 2012-02-03

Family

ID=47217824

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011001209A CL2011001209A1 (en) 2011-05-24 2011-05-24 Method in vitro to determine prognosis of a papillary thyroid cancer that includes quantifying, in a sample, the expression of the chemokine receptor ccr3 and where its overexpression with respect to a reference value indicates that the tumor is highly likely to invade the capsule and generate metastasis.

Country Status (2)

Country Link
CL (1) CL2011001209A1 (en)
WO (1) WO2012160519A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240052422A1 (en) 2020-12-24 2024-02-15 Pontificia Universidad Catolica De Chile In-vitro method for diagnosing and predicting the aggressiveness of thyroid cancer, and the precision surgery options and type to be used to remove a tumour from a patient; kit; reagents forming the kit; and use of the reagents and use of molecular markers as part of the method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399206B2 (en) * 2008-07-10 2013-03-19 Nodality, Inc. Methods for diagnosis, prognosis and methods of treatment

Also Published As

Publication number Publication date
WO2012160519A3 (en) 2013-01-31
WO2012160519A2 (en) 2012-11-29

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