CL2008003820A1 - Metodo para producir el virus de estomatitis vesicular atenuado (vsv) en un cultivo celular que comprende introducir en un vector el gen vsv g optimizado; composicion inmunogenica que comprende el vsv atenuado; kit para producir el vsv. - Google Patents

Metodo para producir el virus de estomatitis vesicular atenuado (vsv) en un cultivo celular que comprende introducir en un vector el gen vsv g optimizado; composicion inmunogenica que comprende el vsv atenuado; kit para producir el vsv.

Info

Publication number
CL2008003820A1
CL2008003820A1 CL2008003820A CL2008003820A CL2008003820A1 CL 2008003820 A1 CL2008003820 A1 CL 2008003820A1 CL 2008003820 A CL2008003820 A CL 2008003820A CL 2008003820 A CL2008003820 A CL 2008003820A CL 2008003820 A1 CL2008003820 A1 CL 2008003820A1
Authority
CL
Chile
Prior art keywords
vsv
attenuated
gene
kit
vector
Prior art date
Application number
CL2008003820A
Other languages
English (en)
Spanish (es)
Inventor
Christopher Parks
Susan Witko
Maninder K Sidhu
J Erik Johnson
Roger Michael Hendry
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40431947&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2008003820(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CL2008003820A1 publication Critical patent/CL2008003820A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20251—Methods of production or purification of viral material
    • C12N2760/20252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261—Methods of inactivation or attenuation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CL2008003820A 2007-12-20 2008-12-19 Metodo para producir el virus de estomatitis vesicular atenuado (vsv) en un cultivo celular que comprende introducir en un vector el gen vsv g optimizado; composicion inmunogenica que comprende el vsv atenuado; kit para producir el vsv. CL2008003820A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1537507P 2007-12-20 2007-12-20

Publications (1)

Publication Number Publication Date
CL2008003820A1 true CL2008003820A1 (es) 2009-07-31

Family

ID=40431947

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003820A CL2008003820A1 (es) 2007-12-20 2008-12-19 Metodo para producir el virus de estomatitis vesicular atenuado (vsv) en un cultivo celular que comprende introducir en un vector el gen vsv g optimizado; composicion inmunogenica que comprende el vsv atenuado; kit para producir el vsv.

Country Status (8)

Country Link
US (1) US20090175900A1 (https=)
EP (1) EP2225368A1 (https=)
JP (1) JP2011507515A (https=)
AR (1) AR069884A1 (https=)
AU (1) AU2008343925B2 (https=)
CA (1) CA2710356A1 (https=)
CL (1) CL2008003820A1 (https=)
WO (1) WO2009085178A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2744894A4 (en) * 2011-08-18 2015-04-22 Ycine Llc PRODUCTION OF INFECTIOUS RNA VIRUSES IN YEAST
EP3708176A1 (en) * 2019-03-15 2020-09-16 Centre National De La Recherche Scientifique -Cnrs- Mutant vsv ectodomain polypeptide and uses thereof
CN113559254B (zh) * 2021-08-09 2023-02-10 苏州大学 一种狂犬病毒疫苗及其制备方法
CN115725657B (zh) * 2022-09-16 2024-06-04 中国科学院广州生物医药与健康研究院 一种节段化的水泡性口炎病毒载体及其制备方法和应用
CN118421571A (zh) * 2024-02-01 2024-08-02 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 表达尼帕病毒囊膜糖蛋白的嵌合型vsv重组病毒及其应用
CN120966775B (zh) * 2025-10-21 2026-02-03 浙江迪福润丝生物科技股份有限公司 一种携带马尔堡病毒缺陷型g蛋白的无神经毒性vsv载体重组溶瘤病毒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) * 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
JP4198195B2 (ja) * 1997-05-02 2008-12-17 ザ ユーエイビー リサーチ ファンデイション 負鎖ｒｎａウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用
US6596529B1 (en) * 1997-05-02 2003-07-22 Uab Research Foundation Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
CN1871355B (zh) * 2003-06-09 2011-12-14 惠氏 从cDNA中回收非节段性负链RNA病毒的改进方法

Also Published As

Publication number Publication date
WO2009085178A1 (en) 2009-07-09
EP2225368A1 (en) 2010-09-08
AU2008343925A8 (en) 2010-07-22
AU2008343925A1 (en) 2009-07-09
AR069884A1 (es) 2010-02-24
CA2710356A1 (en) 2009-07-09
US20090175900A1 (en) 2009-07-09
AU2008343925B2 (en) 2013-01-10
JP2011507515A (ja) 2011-03-10

Similar Documents

Publication Publication Date Title
ATE542803T1 (de) Verfahren zur herstellung von dihydrochinazolinen
GB2477847B (en) Improvements in or relating to methods of manufacture
CO6290704A2 (es) Virus de la estomatitis vesicular (vsv) atenuado y geneticamente modificado y composiciones inmunogenicas que lo contienen.
MY194500A (en) Methods and Compositions for Producing Fatty Alcohols
MX2009000520A (es) Metodos para producir combustibles y solventes.
CL2008003020A1 (es) Metodo para producir el virus de la estomatitis vesicular (vsv) atenuado, que comprende generar celulas que expresan la proteina g de la vsv a partir de un gen vsv optimizado, infectar dichas celulas con el vsv atenuado, y recuperar los virus dle cultivo; composicion que comprende al virus atenuado y kit para producir el virus.
TW200712049A (en) Process for transesterification
CL2008003820A1 (es) Metodo para producir el virus de estomatitis vesicular atenuado (vsv) en un cultivo celular que comprende introducir en un vector el gen vsv g optimizado; composicion inmunogenica que comprende el vsv atenuado; kit para producir el vsv.
MY142818A (en) Process for preparing alkyl (meth)acrylates
EA201000974A1 (ru) Способ усиления иммунореактивности
MX360301B (es) Moleculas pequeñas que contienen boro como agentes antiinflamatorios.
AR067355A1 (es) Procesos para la preparacion de pirazoles
EP2154244A4 (en) CELL CULTURE PROCEDURE USING AMINO ACID-ENRICHED MEDIUM
DK2089516T3 (da) Fremgangsmåder til at forbedre indføringen af DNA i bakterielle celler
BRPI0816911A8 (pt) Processo para preparação de 4-aminobut-2-enolidas
MX2007004642A (es) Combinaciones polimericas para producir peliculas con un numero reducido de defectos.
DE602005027859D1 (de) An ein substrat gebundene dendrimere
AR079704A1 (es) Anticuerpos anti-bv8 y sus usos
UA96994C2 (ru) Производные 7-алкинил-1,8-нафтиридонов, способ их получения и их применения в терапии
CL2008003821A1 (es) Metodo para producir el virus de la estomatitis vesicular (vsv) atenuado en celulas, que comprende: a) proporcionar una celula que comprende un gen g vsv optimizado e inducible, b) inducir la celula a expresar dicho gen, c) infectar la celula con un vsv atenuado, d) hacer crecer dichas celulas, y e) recuperar el vsv atenuado
ATE504554T1 (de) Verfahren zur substitution von indenofluorenen
CY1112029T1 (el) Συνθετο νουκλεϊνικο οξυ και συνθεση απελευθερωσης νουκλεϊνικου οξεος
TW200704630A (en) Novel organic compound and method for producing radioactive halogen-labeled organic compound using the same
UA97143C2 (ru) КОМПОЗИЦИЯ НОСИТЕЛЯ ДЛЯ СВОЕВРЕМЕННОЙ ДОСТАВКИ миРНК
MX2009000756A (es) Uso de multiples secuencias potenciadoras de la transformacion para mejorar la eficiencia de la transformacion en planta.