CL2008003692A1 - Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction - Google Patents

Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction

Info

Publication number
CL2008003692A1
CL2008003692A1 CL2008003692A CL2008003692A CL2008003692A1 CL 2008003692 A1 CL2008003692 A1 CL 2008003692A1 CL 2008003692 A CL2008003692 A CL 2008003692A CL 2008003692 A CL2008003692 A CL 2008003692A CL 2008003692 A1 CL2008003692 A1 CL 2008003692A1
Authority
CL
Chile
Prior art keywords
fraction
composition
fsh
bisected
purification method
Prior art date
Application number
CL2008003692A
Other languages
Spanish (es)
Inventor
Gareth Owen
Horacio Croxato
Ethel Velasquez
Anil Sadarangani
Original Assignee
Univ Pontificia Catolica Chile
Inst De Medicina Reproductiva Icmer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pontificia Catolica Chile, Inst De Medicina Reproductiva Icmer filed Critical Univ Pontificia Catolica Chile
Priority to CL2008003692A priority Critical patent/CL2008003692A1/en
Priority to PCT/CL2009/000028 priority patent/WO2010066062A1/en
Publication of CL2008003692A1 publication Critical patent/CL2008003692A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Fracción de hormona folículo estimulante (FSH) con un punto isoeléctrico básico mayor a 4 y cadenas de carbohidratos altamente ramificadas y/o bisectadas; método de purificación de dicha fracción; composición que comprende la fracción; uso de la composición para influir y modificar la proliferación y destino de células.Follicle stimulating hormone (FSH) fraction with a basic isoelectric point greater than 4 and highly branched and / or bisected carbohydrate chains; purification method of said fraction; composition comprising the fraction; use of the composition to influence and modify the proliferation and fate of cells.

CL2008003692A 2008-12-11 2008-12-11 Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction CL2008003692A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CL2008003692A CL2008003692A1 (en) 2008-12-11 2008-12-11 Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction
PCT/CL2009/000028 WO2010066062A1 (en) 2008-12-11 2009-12-11 Basic fsh fraction for use as a cell-proliferation-controlling agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2008003692A CL2008003692A1 (en) 2008-12-11 2008-12-11 Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction

Publications (1)

Publication Number Publication Date
CL2008003692A1 true CL2008003692A1 (en) 2011-05-13

Family

ID=42242285

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003692A CL2008003692A1 (en) 2008-12-11 2008-12-11 Follicle stimulating hormone (fsh) fraction with a basic isoelectric point greater than 4 and a chain of highly branched and / or bisected carbohydrates; purification method of said fraction; composition comprising the fraction

Country Status (2)

Country Link
CL (1) CL2008003692A1 (en)
WO (1) WO2010066062A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537801A (en) * 1999-02-26 2002-11-12 ノボ ノルディスク アクティーゼルスカブ Meiosis-activated sterols increase implantation rate

Also Published As

Publication number Publication date
WO2010066062A1 (en) 2010-06-17
WO2010066062A4 (en) 2010-08-05

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