CH594590A5 - - Google Patents

Info

Publication number
CH594590A5
CH594590A5 CH1070473A CH1070473A CH594590A5 CH 594590 A5 CH594590 A5 CH 594590A5 CH 1070473 A CH1070473 A CH 1070473A CH 1070473 A CH1070473 A CH 1070473A CH 594590 A5 CH594590 A5 CH 594590A5
Authority
CH
Switzerland
Application number
CH1070473A
Inventor
Tsung-Ying Shen
Howard Jones
Bruce Edward Witzel
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH594590A5 publication Critical patent/CH594590A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1070473A 1972-07-21 1973-07-20 CH594590A5 (US20080094685A1-20080424-C00004.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00274038A US3851063A (en) 1972-07-21 1972-07-21 Treatment of pain,fever or inflammation

Publications (1)

Publication Number Publication Date
CH594590A5 true CH594590A5 (US20080094685A1-20080424-C00004.png) 1978-01-13

Family

ID=23046507

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1070473A CH594590A5 (US20080094685A1-20080424-C00004.png) 1972-07-21 1973-07-20

Country Status (8)

Country Link
US (1) US3851063A (US20080094685A1-20080424-C00004.png)
JP (1) JPS4943956A (US20080094685A1-20080424-C00004.png)
CH (1) CH594590A5 (US20080094685A1-20080424-C00004.png)
DE (1) DE2337068A1 (US20080094685A1-20080424-C00004.png)
FR (1) FR2193596B1 (US20080094685A1-20080424-C00004.png)
GB (1) GB1408964A (US20080094685A1-20080424-C00004.png)
NL (1) NL7309424A (US20080094685A1-20080424-C00004.png)
SE (1) SE7309354L (US20080094685A1-20080424-C00004.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT380166B (de) * 1981-02-16 1986-04-25 Ciba Geigy Ag Verfahren zur herstellung topisch applizierbarer pharmazeutischer praeparate, enthaltend salze von alkancarbonsaeuren
US5965619A (en) * 1996-06-13 1999-10-12 Cell Pathways Inc. Method for treating patients having precancerous lesions with substituted indene derivatives
US6063818A (en) * 1996-06-13 2000-05-16 Cell Pathways Inc. Substituted benzylidene indenyl formamides, acetamides and propionamides
US5998477A (en) * 1996-06-13 1999-12-07 Cell Pathways Inc. Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions
US6121321A (en) * 1996-06-13 2000-09-19 Cell Pathways, Inc. Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions
US5948779A (en) * 1997-12-12 1999-09-07 Cell Pathways, Inc. Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes
US6028116A (en) * 1998-04-03 2000-02-22 Cell Pathways, Inc. Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia
US6479493B1 (en) 2001-08-23 2002-11-12 Cell Pathways, Inc. Methods for treatment of type I diabetes
WO2007081694A2 (en) * 2006-01-04 2007-07-19 Southern Research Institute Derivatives of sulindac, use thereof and preparation thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754556A (fr) * 1969-08-08 1971-02-08 Merck & Co Inc Acides indenyl-acetiques et procede pour les

Also Published As

Publication number Publication date
SE7309354L (US20080094685A1-20080424-C00004.png) 1974-01-22
FR2193596B1 (US20080094685A1-20080424-C00004.png) 1976-12-31
GB1408964A (en) 1975-10-08
JPS4943956A (US20080094685A1-20080424-C00004.png) 1974-04-25
US3851063A (en) 1974-11-26
NL7309424A (US20080094685A1-20080424-C00004.png) 1974-01-23
FR2193596A1 (US20080094685A1-20080424-C00004.png) 1974-02-22
DE2337068A1 (de) 1974-02-07

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Legal Events

Date Code Title Description
PL Patent ceased