CH537951A - Process for the preparation of (+) - (cis-1,2-epoxypropyl) phosphonic acid and its derivatives - Google Patents

Process for the preparation of (+) - (cis-1,2-epoxypropyl) phosphonic acid and its derivatives

Info

Publication number
CH537951A
CH537951A CH1569968A CH1569968A CH537951A CH 537951 A CH537951 A CH 537951A CH 1569968 A CH1569968 A CH 1569968A CH 1569968 A CH1569968 A CH 1569968A CH 537951 A CH537951 A CH 537951A
Authority
CH
Switzerland
Prior art keywords
epoxypropyl
cis
derivatives
preparation
phosphonic acid
Prior art date
Application number
CH1569968A
Other languages
German (de)
Inventor
Grant Christensen Burton
Joseph Leanza William
Robert Beattie Thomas
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH537951A publication Critical patent/CH537951A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3826Acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/14Esters of phosphoric acids containing P(=O)-halide groups
    • C07F9/1403Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505Phosphonic acids containing oxirane groups; esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1569968A 1967-10-30 1968-10-21 Process for the preparation of (+) - (cis-1,2-epoxypropyl) phosphonic acid and its derivatives CH537951A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67920367A 1967-10-30 1967-10-30
US72946668A 1968-05-15 1968-05-15

Publications (1)

Publication Number Publication Date
CH537951A true CH537951A (en) 1973-06-15

Family

ID=27102177

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1569968A CH537951A (en) 1967-10-30 1968-10-21 Process for the preparation of (+) - (cis-1,2-epoxypropyl) phosphonic acid and its derivatives

Country Status (19)

Country Link
AT (1) AT300828B (en)
BE (1) BE723072A (en)
BG (1) BG22841A3 (en)
CH (1) CH537951A (en)
CS (1) CS152311B2 (en)
ES (1) ES359539A1 (en)
FI (1) FI56016C (en)
FR (1) FR1605540A (en)
GB (1) GB1239987A (en)
IE (1) IE32717B1 (en)
IL (1) IL30918A (en)
IT (1) IT974518B (en)
LU (1) LU57183A1 (en)
MT (1) MTP581B (en)
NL (1) NL162079C (en)
OA (1) OA03883A (en)
PL (1) PL79406B1 (en)
SE (1) SE372537B (en)
YU (1) YU34531B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA774977B (en) * 1976-09-06 1978-06-28 Sab Soc Etudes Applic Biolog Process for the preparation of 1,2-expoxypropyl-phosphonic acid derivatives
IT1136652B (en) * 1981-06-04 1986-09-03 Crinos Industria Farmaco PHARMACEUTICAL COMPESITION OF PHOSPHOMYCIN IN TABLETS TO SUCK
WO2016029330A1 (en) * 2014-08-26 2016-03-03 北京美倍他药物研究有限公司 Novel phosphonate derivative and medical use thereof

Also Published As

Publication number Publication date
GB1239987A (en) 1971-07-21
LU57183A1 (en) 1969-05-16
NL162079B (en) 1979-11-15
ES359539A1 (en) 1970-11-01
SE372537B (en) 1974-12-23
FI56016C (en) 1979-11-12
IE32717B1 (en) 1973-11-14
FR1605540A (en) 1979-02-23
BG22841A3 (en) 1977-04-20
FI56016B (en) 1979-07-31
CS152311B2 (en) 1973-12-19
IL30918A0 (en) 1968-12-26
BE723072A (en) 1969-04-29
NL6814980A (en) 1969-05-02
OA03883A (en) 1975-08-14
PL79406B1 (en) 1975-06-30
AT300828B (en) 1972-08-10
DE1805678B2 (en) 1973-01-04
YU34531B (en) 1979-09-10
NL162079C (en) 1980-04-15
IT974518B (en) 1974-07-10
IE32717L (en) 1969-04-30
DE1805678A1 (en) 1969-12-11
MTP581B (en) 1969-09-22
IL30918A (en) 1973-03-30
YU251468A (en) 1979-02-28

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS,

PL Patent ceased