CH513924A - Process for the preparation of (+) and (-) (cis-1,2-epoxypropylphosphonic acid and their corresponding salts and esters - Google Patents

Process for the preparation of (+) and (-) (cis-1,2-epoxypropylphosphonic acid and their corresponding salts and esters

Info

Publication number
CH513924A
CH513924A CH743369A CH743369A CH513924A CH 513924 A CH513924 A CH 513924A CH 743369 A CH743369 A CH 743369A CH 743369 A CH743369 A CH 743369A CH 513924 A CH513924 A CH 513924A
Authority
CH
Switzerland
Prior art keywords
cis
esters
preparation
corresponding salts
epoxypropylphosphonic acid
Prior art date
Application number
CH743369A
Other languages
German (de)
Inventor
Immanuel Pollak Peter
Lord Wendler Norman
Grant Christensen Burton
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH513924A publication Critical patent/CH513924A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505Phosphonic acids containing oxirane groups; esters thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564Three-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH743369A 1968-05-15 1969-05-14 Process for the preparation of (+) and (-) (cis-1,2-epoxypropylphosphonic acid and their corresponding salts and esters CH513924A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72942468A 1968-05-15 1968-05-15
US75572968A 1968-08-27 1968-08-27
US81944769A 1969-04-25 1969-04-25

Publications (1)

Publication Number Publication Date
CH513924A true CH513924A (en) 1971-10-15

Family

ID=27419130

Family Applications (1)

Application Number Title Priority Date Filing Date
CH743369A CH513924A (en) 1968-05-15 1969-05-14 Process for the preparation of (+) and (-) (cis-1,2-epoxypropylphosphonic acid and their corresponding salts and esters

Country Status (15)

Country Link
JP (1) JPS4919264B1 (en)
AR (1) AR195479A1 (en)
AT (1) AT306052B (en)
BE (1) BE733050A (en)
CA (1) CA939366A (en)
CH (1) CH513924A (en)
DE (1) DE1924169C3 (en)
ES (2) ES367269A1 (en)
FI (1) FI53216C (en)
FR (1) FR2008620B1 (en)
GB (1) GB1266611A (en)
IE (1) IE32804B1 (en)
IL (1) IL32180A0 (en)
NL (1) NL6907465A (en)
YU (1) YU120469A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937367A (en) * 1987-07-15 1990-06-26 Zambon Group S.P.A. Process for the preparation of intermediates for the synthesis of fosfomycin
CN114540619B (en) * 2020-11-25 2024-02-13 厦门稀土材料研究所 Functional ionic liquid and preparation method and application thereof

Also Published As

Publication number Publication date
IL32180A0 (en) 1969-07-30
JPS4919264B1 (en) 1974-05-16
ES367269A1 (en) 1972-02-16
FR2008620A1 (en) 1970-01-23
DE1924169C3 (en) 1974-02-21
IE32804L (en) 1969-11-15
AT306052B (en) 1973-03-26
DE1924169B2 (en) 1973-07-05
DE1924169A1 (en) 1970-02-05
FR2008620B1 (en) 1975-10-31
AR195479A1 (en) 1973-10-15
YU120469A (en) 1979-10-31
FI53216C (en) 1978-03-10
CA939366A (en) 1974-01-01
BE733050A (en) 1969-11-14
ES395161A1 (en) 1974-11-16
GB1266611A (en) 1972-03-15
FI53216B (en) 1977-11-30
IE32804B1 (en) 1973-12-12
NL6907465A (en) 1969-11-18

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Legal Events

Date Code Title Description
PL Patent ceased