CH507984A - Process for the preparation of 7-acylaminocephalosporanic acids - Google Patents

Process for the preparation of 7-acylaminocephalosporanic acids

Info

Publication number
CH507984A
CH507984A CH411968A CH411968A CH507984A CH 507984 A CH507984 A CH 507984A CH 411968 A CH411968 A CH 411968A CH 411968 A CH411968 A CH 411968A CH 507984 A CH507984 A CH 507984A
Authority
CH
Switzerland
Prior art keywords
preparation
acylaminocephalosporanic
acids
acylaminocephalosporanic acids
Prior art date
Application number
CH411968A
Other languages
German (de)
Inventor
Gibson Long Alan
Mckenzie Wilson Edward
Graham William
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of CH507984A publication Critical patent/CH507984A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CH411968A 1967-03-23 1968-03-20 Process for the preparation of 7-acylaminocephalosporanic acids CH507984A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB03867/67A GB1208014A (en) 1967-03-23 1967-03-23 Cephalosporins

Publications (1)

Publication Number Publication Date
CH507984A true CH507984A (en) 1971-05-31

Family

ID=10030837

Family Applications (1)

Application Number Title Priority Date Filing Date
CH411968A CH507984A (en) 1967-03-23 1968-03-20 Process for the preparation of 7-acylaminocephalosporanic acids

Country Status (7)

Country Link
CH (1) CH507984A (en)
DE (1) DE1770031A1 (en)
DK (1) DK124265B (en)
FR (2) FR7572M (en)
GB (1) GB1208014A (en)
NL (1) NL156702B (en)
SE (1) SE364284B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1389194A (en) * 1971-01-29 1975-04-03 Glaxo Lab Ltd Antibiotics
IE36041B1 (en) * 1971-01-29 1976-08-04 Glaxo Lab Ltd Improvements in or relating to antibiotics
PL102925B1 (en) * 1971-01-29 1979-05-31 METHOD OF PRODUCTION OF NEW DERIVATIVES OF CEPHALOSPORIN
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1575803A (en) * 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
ES467601A1 (en) 1977-03-12 1979-06-16 Hoechst Ag 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation
DE2818263A1 (en) * 1978-04-26 1979-11-08 Bayer Ag BETA LACTAMANTIBIOTICS
IT1211080B (en) * 1981-07-21 1989-09-29 Craf Sud BIOLOGICALLY ACTIVE HYDRAZONOCEFEM.
GB8810393D0 (en) * 1988-05-03 1988-06-08 Glaxo Group Ltd Chemical process
PT2283006E (en) 2008-04-24 2015-06-29 F2G Ltd Pyrrole antifungal agents
EP3221308B1 (en) 2014-11-21 2018-09-19 F2G Limited Antifungal agents
GB201609222D0 (en) 2016-05-25 2016-07-06 F2G Ltd Pharmaceutical formulation
US11819503B2 (en) 2019-04-23 2023-11-21 F2G Ltd Method of treating coccidioides infection

Also Published As

Publication number Publication date
SE364284B (en) 1974-02-18
GB1208014A (en) 1970-10-07
NL6804139A (en) 1968-09-24
FR7572M (en) 1970-01-05
DK124265B (en) 1972-10-02
NL156702B (en) 1978-05-16
FR1556822A (en) 1969-02-07
DE1770031A1 (en) 1971-09-16

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: GLAXO OPERATIONS UK LIMITED

PL Patent ceased