CA999572A - Process for preparing 7-acylamino-3-substituted-3-cephem-4-carboxylic acid derivatives - Google Patents

Process for preparing 7-acylamino-3-substituted-3-cephem-4-carboxylic acid derivatives

Info

Publication number
CA999572A
CA999572A CA159,730A CA159730A CA999572A CA 999572 A CA999572 A CA 999572A CA 159730 A CA159730 A CA 159730A CA 999572 A CA999572 A CA 999572A
Authority
CA
Canada
Prior art keywords
cephem
acylamino
substituted
preparing
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA159,730A
Other versions
CA159730S (en
Inventor
Kazuo Kariyone
Masaru Kurita
Teruo Oku
Hisatoyo Yazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of CA999572A publication Critical patent/CA999572A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
CA159,730A 1971-12-23 1972-12-22 Process for preparing 7-acylamino-3-substituted-3-cephem-4-carboxylic acid derivatives Expired CA999572A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP251772A JPS55392B2 (en) 1971-12-23 1971-12-23

Publications (1)

Publication Number Publication Date
CA999572A true CA999572A (en) 1976-11-09

Family

ID=11531551

Family Applications (1)

Application Number Title Priority Date Filing Date
CA159,730A Expired CA999572A (en) 1971-12-23 1972-12-22 Process for preparing 7-acylamino-3-substituted-3-cephem-4-carboxylic acid derivatives

Country Status (8)

Country Link
JP (1) JPS55392B2 (en)
AT (1) AT328611B (en)
BE (1) BE793037A (en)
CA (1) CA999572A (en)
CH (1) CH578006A5 (en)
DE (1) DE2262262C2 (en)
FR (1) FR2170496A5 (en)
NL (1) NL7217630A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989694A (en) * 1974-12-27 1976-11-02 Smithkline Corporation 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
ZA76451B (en) * 1975-02-27 1977-01-26 Smithkline Corp New cephalosporin compounds
US4220644A (en) 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
GB1555335A (en) * 1976-05-14 1979-11-07 Beecham Group Ltd 3-(carboxymethyl substituted-heterocyclicthio)-cephalosporins methods for their preparation and compositions containing them
EP0027599B1 (en) * 1979-10-12 1984-10-03 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
GB9726989D0 (en) * 1997-12-22 1998-02-18 Ciba Geigy Ag Organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143030C (en) * 1968-07-01 1981-10-12 Bristol Myers Co PROCEDURE FOR IN-SITU PREPARATION OF A CEPHALOSPORIN C DERIVATE
DE1953861C2 (en) * 1969-10-25 1982-12-23 Fujisawa Pharmaceutical Co., Ltd., Osaka 7-tetrazolylacetamido-3-thiomethyl-3-cephem-4-carboxylic acids
BE758587A (en) * 1969-11-17 1971-05-06 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES AND NEW PRODUCTS THUS OBTAINED
BE759064A (en) * 1969-12-17 1971-05-17 Lilly Co Eli A METHOD FOR TRANSFORMING CEPHALOSPORIN C. INTO A DERIVATIVE SOLUBLE IN AN ORGANIC SOLVENT, AND THE COMPOUND WHICH IS

Also Published As

Publication number Publication date
DE2262262A1 (en) 1973-06-28
JPS4868592A (en) 1973-09-18
BE793037A (en) 1973-06-20
FR2170496A5 (en) 1973-09-14
NL7217630A (en) 1973-06-26
DE2262262C2 (en) 1986-09-11
ATA1092972A (en) 1975-06-15
CH578006A5 (en) 1976-07-30
JPS55392B2 (en) 1980-01-08
AT328611B (en) 1976-03-25

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