CA994327A - PROCESS FOR PREPARING 7-(.alpha.-HYDROXY-.alpha.-PHENYL) ACETAMIDO-3-(1-METHYL-1H-TETRAZOL-5-XYLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND DERIVATIVES THEREOF - Google Patents
PROCESS FOR PREPARING 7-(.alpha.-HYDROXY-.alpha.-PHENYL) ACETAMIDO-3-(1-METHYL-1H-TETRAZOL-5-XYLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND DERIVATIVES THEREOFInfo
- Publication number
- CA994327A CA994327A CA165,968A CA165968A CA994327A CA 994327 A CA994327 A CA 994327A CA 165968 A CA165968 A CA 165968A CA 994327 A CA994327 A CA 994327A
- Authority
- CA
- Canada
- Prior art keywords
- alpha
- xylthiomethyl
- cephem
- tetrazol
- acetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00236764A US3840531A (en) | 1972-03-21 | 1972-03-21 | Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA994327A true CA994327A (en) | 1976-08-03 |
Family
ID=22890856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA165,968A Expired CA994327A (en) | 1972-03-21 | 1973-03-13 | PROCESS FOR PREPARING 7-(.alpha.-HYDROXY-.alpha.-PHENYL) ACETAMIDO-3-(1-METHYL-1H-TETRAZOL-5-XYLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIC ACID AND DERIVATIVES THEREOF |
Country Status (28)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1449420A (en) * | 1973-11-26 | 1976-09-15 | Sankyo Co | 7alpha-methoxycephalosporing derivatives |
| DE2512284A1 (de) * | 1974-03-28 | 1975-10-09 | Fujisawa Pharmaceutical Co | Cephalosporansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
| US3933808A (en) * | 1974-05-20 | 1976-01-20 | Eli Lilly And Company | Cephalosporin esters |
| US3928334A (en) * | 1974-06-06 | 1975-12-23 | Bristol Myers Co | Process for the production of cefamandole |
| US3928337A (en) * | 1974-08-07 | 1975-12-23 | Bristol Myers Co | Process for the production of cefamandole |
| US3947415A (en) * | 1974-12-23 | 1976-03-30 | Eli Lilly And Company | Cefamandole derivatives |
| US3947414A (en) * | 1974-12-23 | 1976-03-30 | Eli Lilly And Company | Cefamandole derivatives |
| US4035361A (en) * | 1976-03-17 | 1977-07-12 | Eli Lilly And Company | Bis-trimethylsilyl cefamandole and process therefor |
| GB1565941A (en) * | 1977-02-08 | 1980-04-23 | Toyama Chemical Co Ltd | Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids |
| US4115644A (en) * | 1977-09-19 | 1978-09-19 | Eli Lilly And Company | Process for preparing pure cefamandole from alkali metal and ammonium salts thereof |
| JPS6027677B2 (ja) * | 1978-07-06 | 1985-06-29 | 富山化学工業株式会社 | ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法 |
| JPS5543043A (en) * | 1978-09-22 | 1980-03-26 | Sankyo Co Ltd | Preparation of 3-substituted thiomethylcephalosporin derivative |
| US4351947A (en) * | 1980-03-06 | 1982-09-28 | Asahi Chemical Industry Co., Ltd. | Tetrazole derivative |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3167549A (en) * | 1961-05-18 | 1965-01-26 | Smith Kline French Lab | Derivatives of 7-aminocephalosporanic acid |
-
1972
- 1972-03-21 US US00236764A patent/US3840531A/en not_active Expired - Lifetime
-
1973
- 1973-03-06 GB GB1082673A patent/GB1400697A/en not_active Expired
- 1973-03-06 IL IL41711A patent/IL41711A/en unknown
- 1973-03-07 AU AU53060/73A patent/AU465689B2/en not_active Expired
- 1973-03-08 ZA ZA731644A patent/ZA731644B/xx unknown
- 1973-03-13 IE IE404/73A patent/IE37402B1/xx unknown
- 1973-03-13 CA CA165,968A patent/CA994327A/en not_active Expired
- 1973-03-15 DE DE2312997A patent/DE2312997A1/de active Pending
- 1973-03-15 BE BE1004892A patent/BE796788A/xx unknown
- 1973-03-15 SE SE7303601A patent/SE416473B/xx unknown
- 1973-03-16 YU YU710/73A patent/YU35601B/xx unknown
- 1973-03-16 PH PH14434*UA patent/PH9650A/en unknown
- 1973-03-19 HU HUEI468A patent/HU165339B/hu unknown
- 1973-03-20 BR BR731970A patent/BR7301970D0/pt unknown
- 1973-03-20 DD DD169574A patent/DD105240A5/xx unknown
- 1973-03-20 CH CH404573A patent/CH557382A/fr not_active IP Right Cessation
- 1973-03-20 NL NL7303917A patent/NL7303917A/xx unknown
- 1973-03-20 ES ES412859A patent/ES412859A1/es not_active Expired
- 1973-03-20 SU SU731899018A patent/SU632295A3/ru active
- 1973-03-20 RO RO7300074233A patent/RO62621A/ro unknown
- 1973-03-20 CS CS7300002032A patent/CS182782B2/cs unknown
- 1973-03-20 AR AR247144A patent/AR193934A1/es active
- 1973-03-20 DK DK150273A patent/DK143854C/da active
- 1973-03-20 AT AT246073A patent/AT330347B/de not_active IP Right Cessation
- 1973-03-21 PL PL1973161410A patent/PL85244B1/pl unknown
- 1973-03-21 FR FR7310112A patent/FR2182884B1/fr not_active Expired
- 1973-03-21 BG BG023051A patent/BG20609A3/xx unknown
- 1973-03-22 JP JP3197673A patent/JPS5541237B2/ja not_active Expired
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