CA989827A - Process for the preparation of 14-hydroxymorphinan derivatives - Google Patents
Process for the preparation of 14-hydroxymorphinan derivativesInfo
- Publication number
- CA989827A CA989827A CA170,185A CA170185A CA989827A CA 989827 A CA989827 A CA 989827A CA 170185 A CA170185 A CA 170185A CA 989827 A CA989827 A CA 989827A
- Authority
- CA
- Canada
- Prior art keywords
- preparation
- hydroxymorphinan derivatives
- hydroxymorphinan
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA238,018A CA989828A (en) | 1972-05-10 | 1975-10-21 | Process for the preparation of 14-hydroxymorphinan derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25187972A | 1972-05-10 | 1972-05-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA989827A true CA989827A (en) | 1976-05-25 |
Family
ID=22953785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA170,185A Expired CA989827A (en) | 1972-05-10 | 1973-05-01 | Process for the preparation of 14-hydroxymorphinan derivatives |
Country Status (13)
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3910920A (en) * | 1973-11-07 | 1975-10-07 | Bristol Myers Co | 3,14,17-Substituted-6,7-tetramethylenemorphinans |
US3980641A (en) * | 1975-07-31 | 1976-09-14 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinans |
US4017497A (en) * | 1975-11-18 | 1977-04-12 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
JPS52136176A (en) * | 1976-03-23 | 1977-11-14 | Bristol Myers Co | Method of improving 144hydroxymorphinan derivatives |
US4139534A (en) * | 1977-02-17 | 1979-02-13 | Bristol-Myers Company | Process for the preparation of 14-hydroxymorphinan derivatives |
US4052389A (en) * | 1976-03-23 | 1977-10-04 | Bristol-Myers Company | Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one |
US4115389A (en) * | 1977-05-02 | 1978-09-19 | Bristol-Myers Company | Process of N-demethylating (-)-1-(p-methoxybenzyl)-2-methyl-1,2,3,4,5,6,7,8-octahydroisoquinoline |
NO793297L (no) * | 1978-10-19 | 1980-04-22 | Mallinckrodt Inc | Fremgangsmaate til fremstilling av oksymorfon |
US4272540A (en) * | 1979-04-24 | 1981-06-09 | Sisa, Incorporated | 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them |
NO802139L (no) * | 1979-08-09 | 1981-02-10 | Mallinckrodt Inc | Utgangsforbindelser for fremstilling av morfinderivater, samt fremgangsmaate til fremstilling av utgangsforbindelsene |
US5109136A (en) * | 1990-08-09 | 1992-04-28 | Warner-Lambert Company | Tetracyclic amines useful as cerebrovascular agents |
WO2016060122A1 (ja) | 2014-10-14 | 2016-04-21 | 久光製薬株式会社 | 貼付剤 |
AU2017242268A1 (en) * | 2016-03-29 | 2018-10-25 | Hikal Limited | An improved process for the preparation of butorphanol tartrate |
WO2018123822A1 (ja) | 2016-12-28 | 2018-07-05 | 久光製薬株式会社 | ブトルファノール含有貼付剤 |
CN110545816B (zh) | 2017-04-25 | 2023-04-11 | 久光制药株式会社 | 贴附剂 |
CN110573160B (zh) | 2017-04-25 | 2022-11-18 | 久光制药株式会社 | 贴附剂 |
CN112592342B (zh) * | 2021-01-15 | 2022-02-22 | 福安药业集团重庆礼邦药物开发有限公司 | 一种布托啡诺脱环丁基杂质化合物的制备方法 |
-
1972
- 1972-05-10 US US00251879A patent/US3775414A/en not_active Expired - Lifetime
-
1973
- 1973-05-01 CA CA170,185A patent/CA989827A/en not_active Expired
- 1973-05-07 YU YU01197/73A patent/YU36505B/xx unknown
- 1973-05-07 NL NL737306344A patent/NL155256B/xx unknown
- 1973-05-08 DD DD170682A patent/DD106841A5/xx unknown
- 1973-05-08 CH CH652673A patent/CH590238A5/xx not_active IP Right Cessation
- 1973-05-08 SE SE7306479A patent/SE403106B/xx unknown
- 1973-05-08 IL IL42219A patent/IL42219A/en unknown
- 1973-05-09 JP JP5080073A patent/JPS535672B2/ja not_active Expired
- 1973-05-09 OA OA54906A patent/OA04406A/xx unknown
- 1973-05-10 DK DK259373AA patent/DK138492B/da unknown
- 1973-05-10 CS CS7424A patent/CS178447B2/cs unknown
- 1973-05-10 HU HUBI470A patent/HU168597B/hu unknown
- 1973-05-10 CS CS3317A patent/CS178425B2/cs unknown
- 1973-05-10 CS CS7423A patent/CS178446B2/cs unknown
- 1973-05-10 HU HUBI513A patent/HU169023B/hu unknown
-
1976
- 1976-04-08 SE SE7604162A patent/SE411042B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE7604162L (sv) | 1976-04-08 |
HU168597B (US07413550-20080819-C00001.png) | 1976-06-28 |
NL155256B (nl) | 1977-12-15 |
OA04406A (fr) | 1980-02-29 |
IL42219A0 (en) | 1973-07-30 |
SE403106B (sv) | 1978-07-31 |
NL7306344A (US07413550-20080819-C00001.png) | 1973-11-13 |
CS178447B2 (US07413550-20080819-C00001.png) | 1977-09-15 |
JPS535672B2 (US07413550-20080819-C00001.png) | 1978-03-01 |
YU119773A (en) | 1982-02-25 |
SE411042B (sv) | 1979-11-26 |
YU36505B (en) | 1984-02-29 |
DK138492B (da) | 1978-09-18 |
CS178425B2 (US07413550-20080819-C00001.png) | 1977-09-15 |
CS178446B2 (US07413550-20080819-C00001.png) | 1977-09-15 |
IL42219A (en) | 1977-06-30 |
DK138492C (US07413550-20080819-C00001.png) | 1979-02-19 |
HU169023B (US07413550-20080819-C00001.png) | 1976-09-28 |
CH590238A5 (US07413550-20080819-C00001.png) | 1977-07-29 |
JPS4961169A (US07413550-20080819-C00001.png) | 1974-06-13 |
US3775414A (en) | 1973-11-27 |
DD106841A5 (US07413550-20080819-C00001.png) | 1974-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA989827A (en) | Process for the preparation of 14-hydroxymorphinan derivatives | |
CA979449A (en) | Process for the preparation of 1-hydroxy-2-pyridones | |
CA995682A (en) | Process for the preparation of 3-cyanochromones | |
CA1003410A (en) | Process for the preparation of alpha-6-deoxytetracyclines | |
AU471441B2 (en) | Process for the preparation of 2-hydrazino-benzothiazoles | |
CA989868A (en) | Process for the preparation of isopropylamines | |
AU474746B2 (en) | Process for the preparation of thiazole-sulphenamides | |
AU472802B2 (en) | Process for the preparation of 3-nitro-4-amino-toluene | |
CA993871A (en) | Process for the preparation of certain indolobenzazepine derivatives | |
CA1006181A (fr) | Procede de preparation de nouveaux derives de l'amino-propane | |
CA992967A (en) | Process for the preparation of eburnamonines | |
CA1018182A (en) | Process for the preparation of alkylene-bis-amides | |
CA1010860A (en) | Process for the manufacture of new anhydrofuranose derivatives | |
CA1019097A (en) | Process for the preparation of trans-polyalkenamers | |
CA1005058A (en) | Process for the preparation of unsymmetrically-substituted alkanolamino-s-triazines | |
CA999867A (en) | Process for the preparation of 2h-3-isoquinolones | |
CA1006114A (en) | Process for the preparation of chloroiminophosgene | |
CA996109A (en) | Process for the preparation of 2-amino-benzylamines | |
CA972372A (en) | Process for the preparation of aminoalkyleneindolines | |
CA989828A (en) | Process for the preparation of 14-hydroxymorphinan derivatives | |
CA913104A (en) | Process for the preparation of isoquinuclidine derivatives | |
CA913103A (en) | Process for the preparation of isoquinuclidine derivatives | |
CA894805A (en) | Process for the preparation of dibenzo-cycloheptene derivatives | |
CA915161A (en) | Process for the preparation of 7-nitro-estratrienes | |
CA1006179A (en) | Process for the preparation of chloroiminophosgene |