CA972749A - Derivatives of 9-oxo-15-hydroxyprostanoic acid, homologs thereof and their preparation - Google Patents

Derivatives of 9-oxo-15-hydroxyprostanoic acid, homologs thereof and their preparation

Info

Publication number
CA972749A
CA972749A CA119,467A CA119467A CA972749A CA 972749 A CA972749 A CA 972749A CA 119467 A CA119467 A CA 119467A CA 972749 A CA972749 A CA 972749A
Authority
CA
Canada
Prior art keywords
homologs
oxo
derivatives
preparation
hydroxyprostanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA119,467A
Other languages
English (en)
Other versions
CA119467S (en
Inventor
Jehan F. Bagli
Tibor Bogri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Application granted granted Critical
Publication of CA972749A publication Critical patent/CA972749A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • C07C59/215—Saturated compounds having only one carboxyl group and containing keto groups containing singly bound oxygen containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA119,467A 1970-07-30 1971-07-29 Derivatives of 9-oxo-15-hydroxyprostanoic acid, homologs thereof and their preparation Expired CA972749A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5970270A 1970-07-30 1970-07-30

Publications (1)

Publication Number Publication Date
CA972749A true CA972749A (en) 1975-08-12

Family

ID=22024690

Family Applications (1)

Application Number Title Priority Date Filing Date
CA119,467A Expired CA972749A (en) 1970-07-30 1971-07-29 Derivatives of 9-oxo-15-hydroxyprostanoic acid, homologs thereof and their preparation

Country Status (7)

Country Link
US (1) US3671570A (es)
CA (1) CA972749A (es)
CH (1) CH573896A5 (es)
DE (1) DE2137811C3 (es)
FR (1) FR2100971B1 (es)
NL (1) NL7110590A (es)
SE (1) SE375984B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903299A (en) * 1970-05-27 1975-09-02 May & Baker Ltd Pharmaceutical compositions containing cyclopentane derivatives
US3907998A (en) * 1971-06-28 1975-09-23 Ayerst Mckenna & Harrison Methods for relieving bronchial spasm with 9,15-dioxygenated prostanoic and prost-13-enoic acids and the like
US3987087A (en) * 1971-07-29 1976-10-19 The Upjohn Company Phenyl-substituted prostaglandin-f type analogs
US3956284A (en) * 1972-07-13 1976-05-11 Pfizer Inc. Heterocyclic 15-substituted-ω-pentanorprostoglandins
US3974213A (en) * 1972-07-13 1976-08-10 Pfizer Inc. 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins
US4011262A (en) * 1972-07-13 1977-03-08 Pfizer Inc. 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins of the two series
US3971826A (en) * 1972-07-13 1976-07-27 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
CA1018970A (en) * 1972-10-27 1977-10-11 American Home Products Corporation 15-substituted prostanoic acids
US3972917A (en) * 1972-10-27 1976-08-03 American Home Products Corporation 11-Deoxy 15-methyl prostaglandin E1
US4152527A (en) * 1972-11-08 1979-05-01 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
US3932463A (en) * 1974-06-03 1976-01-13 American Cyanamid Company 11-Deoxy-13-dihydro-prostaglandin-9-ketals
US4036832A (en) * 1974-07-03 1977-07-19 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
GB1499253A (en) * 1975-02-14 1978-01-25 Upjohn Co Prostaglandins
US4054741A (en) * 1975-06-27 1977-10-18 Ayerst Mckenna & Harrison Ltd. Derivatives of prostanoic acid
NZ561414A (en) * 2005-03-04 2010-10-29 Sucampo Ag Method and composition for treating peripheral vascular diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1097533A (en) * 1965-08-16 1968-01-03 Upjohn Co Prostanoic acid derivatives
GB1198071A (en) * 1966-08-09 1970-07-08 George Erich Just Improvements in or relating to Prostaglandin Analogues and the Manufacture thereof

Also Published As

Publication number Publication date
FR2100971A1 (es) 1972-03-24
CH573896A5 (es) 1976-03-31
DE2137811C3 (de) 1980-10-30
FR2100971B1 (es) 1975-02-07
DE2137811A1 (es) 1972-02-03
NL7110590A (es) 1972-02-01
US3671570A (en) 1972-06-20
DE2137811B2 (es) 1980-02-28
SE375984B (es) 1975-05-05

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