CA3247035A1 - COMBINATION OF NITROUS OXIDE AND 5-HT2A RECEPTOR AGONISTS - Google Patents

COMBINATION OF NITROUS OXIDE AND 5-HT2A RECEPTOR AGONISTS

Info

Publication number
CA3247035A1
CA3247035A1 CA3247035A CA3247035A CA3247035A1 CA 3247035 A1 CA3247035 A1 CA 3247035A1 CA 3247035 A CA3247035 A CA 3247035A CA 3247035 A CA3247035 A CA 3247035A CA 3247035 A1 CA3247035 A1 CA 3247035A1
Authority
CA
Canada
Prior art keywords
substituted
unsubstituted
methyl
indol
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3247035A
Other languages
English (en)
French (fr)
Inventor
Michael Palfreyman
Alex Nivorozhkin
Brett J. GREENE
Robert Mino
Amy Claire Reichelt
Geoffrey B. Varty
Original Assignee
Cybin IRL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cybin IRL Ltd filed Critical Cybin IRL Ltd
Publication of CA3247035A1 publication Critical patent/CA3247035A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA3247035A 2022-03-31 2023-03-29 COMBINATION OF NITROUS OXIDE AND 5-HT2A RECEPTOR AGONISTS Pending CA3247035A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263362258P 2022-03-31 2022-03-31
US63/362,258 2022-03-31
PCT/EP2023/058107 WO2023186963A1 (en) 2022-03-31 2023-03-29 Combination of nitrous oxide and 5-ht2a receptor agonists

Publications (1)

Publication Number Publication Date
CA3247035A1 true CA3247035A1 (en) 2023-10-05

Family

ID=86007250

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3247035A Pending CA3247035A1 (en) 2022-03-31 2023-03-29 COMBINATION OF NITROUS OXIDE AND 5-HT2A RECEPTOR AGONISTS

Country Status (5)

Country Link
EP (1) EP4499087A1 (enExample)
JP (1) JP2025510942A (enExample)
AU (1) AU2023242469A1 (enExample)
CA (1) CA3247035A1 (enExample)
WO (1) WO2023186963A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023539113A (ja) 2020-08-18 2023-09-13 サイビン アイアールエル リミテッド フェネチルアミン誘導体、組成物およびその使用方法
EP4396162A4 (en) 2021-09-03 2025-11-12 Alexander Shulgin Res Institute Inc ASYMMETRIC ALLYL TRYPTAMINES
WO2024108195A1 (en) 2022-11-17 2024-05-23 Remedi, Inc. Combinations of monoamine oxidase inhibitors and serotonin receptor agonists and their therapeutic use
KR20260003282A (ko) * 2023-05-05 2026-01-06 사이빈 아이알엘 리미티드 주사식 약학적 제형
TW202519206A (zh) * 2023-11-06 2025-05-16 大陸商宜昌人福藥業有限責任公司 一種n,n-二甲基色胺衍生物及其藥物組合物、製備方法和用途
WO2025099725A1 (en) * 2023-11-09 2025-05-15 Hadasit Medical Research Services And Development Ltd. Conjugates and uses thereof

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US5612059A (en) 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
DE4023108C1 (enExample) 1990-07-20 1992-02-13 Ems Gmbh, 8520 Moehrendorf, De
US5798119A (en) 1995-06-13 1998-08-25 S. C. Johnson & Son, Inc. Osmotic-delivery devices having vapor-permeable coatings
US6488648B1 (en) 1999-01-14 2002-12-03 Teijin Limited Device for feeding a powder in a predetermined amount and method thereof
GB0121568D0 (en) 2001-09-06 2001-10-24 Optinose As Nasal delivery device
NZ514442A (en) 1999-03-03 2003-08-29 Optinose As Nasal delivery device
GB0114272D0 (en) 2001-06-12 2001-08-01 Optinose As Nasal delivery device
GB0019715D0 (en) 2000-08-10 2000-09-27 Pa Consulting Services Device for delivering physiologically active agent in powdered form
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
AU2002340083A1 (en) 2001-09-28 2003-04-07 Kurve Technology, Inc Nasal nebulizer
GB0207422D0 (en) 2002-03-28 2002-05-08 Optinose As Nasal devices
GB0207817D0 (en) 2002-04-04 2002-05-15 Optinose As Nasal devices
GB0209494D0 (en) 2002-04-25 2002-06-05 Optinose As Nasal devices
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US8826905B2 (en) 2007-06-01 2014-09-09 Ramses Nashed Respiratory face mask and breathing circuit assembly
US20100192947A1 (en) 2009-02-04 2010-08-05 Jeff Mandel Anesthetic delivery system and methods of use
AU2011217687B2 (en) 2010-02-22 2013-05-09 Class 1 Inc. Apparatus, systems and methods for collecting and reclaiming anaesthetic agents and for removing nitrous oxide from exhaust gases
EP2589403B1 (en) 2011-05-31 2016-02-03 Ishikita, Naoyuki Anesthetic inhalation-assisting device
KR20220008824A (ko) * 2019-04-17 2022-01-21 컴퍼스 패쓰파인더 리미티드 실로시빈으로 불안 장애, 두통 장애 및 섭식 장애를 치료하는 방법
WO2021116503A2 (en) * 2020-06-02 2021-06-17 Small Pharma Ltd Deuterated compounds
RU199823U1 (ru) 2020-06-10 2020-09-21 Общество С Ограниченной Ответственностью "Центр Передовых Радиационных Медицинских И Биологических Технологий Устройство для лечения бронхолегочных заболеваний

Also Published As

Publication number Publication date
EP4499087A1 (en) 2025-02-05
AU2023242469A1 (en) 2024-09-05
JP2025510942A (ja) 2025-04-15
WO2023186963A1 (en) 2023-10-05

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