CA3243958A1 - METHODS AND COMPOSITIONS TO IMPROVE EXERCISE PERFORMANCE - Google Patents

METHODS AND COMPOSITIONS TO IMPROVE EXERCISE PERFORMANCE

Info

Publication number
CA3243958A1
CA3243958A1 CA3243958A CA3243958A CA3243958A1 CA 3243958 A1 CA3243958 A1 CA 3243958A1 CA 3243958 A CA3243958 A CA 3243958A CA 3243958 A CA3243958 A CA 3243958A CA 3243958 A1 CA3243958 A1 CA 3243958A1
Authority
CA
Canada
Prior art keywords
fontan
udenafil
patient
peak
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3243958A
Other languages
English (en)
French (fr)
Inventor
James L. Yeager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Mezzion Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mezzion Pharma Co Ltd filed Critical Mezzion Pharma Co Ltd
Publication of CA3243958A1 publication Critical patent/CA3243958A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3243958A 2021-12-20 2022-12-20 METHODS AND COMPOSITIONS TO IMPROVE EXERCISE PERFORMANCE Pending CA3243958A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163291858P 2021-12-20 2021-12-20
US63/291,858 2021-12-20
PCT/US2022/000033 WO2023121689A1 (en) 2021-12-20 2022-12-20 Methods and compositions for improving exercise performance

Publications (1)

Publication Number Publication Date
CA3243958A1 true CA3243958A1 (en) 2023-06-29

Family

ID=85382567

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3243958A Pending CA3243958A1 (en) 2021-12-20 2022-12-20 METHODS AND COMPOSITIONS TO IMPROVE EXERCISE PERFORMANCE

Country Status (8)

Country Link
US (1) US20240285630A1 (https=)
EP (1) EP4452273A1 (https=)
JP (1) JP2025504706A (https=)
CN (1) CN119072312A (https=)
AU (1) AU2022419178A1 (https=)
CA (1) CA3243958A1 (https=)
MX (1) MX2024007796A (https=)
WO (1) WO2023121689A1 (https=)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TN2017000029A1 (en) 2014-08-12 2018-07-04 Mezzion Pharma Co Ltd Methods of improving myocardial performance in fontan patients using udenafil compositions
AU2020356193A1 (en) * 2019-09-24 2022-05-19 Children's Hospital Of Philadelphia Methods of improving exercise performance, single ventricular performance, and myocardial performance index (MPI) in single ventricle heart disease, using udenafil compositions

Also Published As

Publication number Publication date
MX2024007796A (es) 2025-04-02
EP4452273A1 (en) 2024-10-30
US20240285630A1 (en) 2024-08-29
JP2025504706A (ja) 2025-02-17
CN119072312A (zh) 2024-12-03
AU2022419178A1 (en) 2024-08-08
WO2023121689A1 (en) 2023-06-29

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