CA3240044A1 - Nitric oxide-releasing nasal compositions and methods of use thereof - Google Patents

Nitric oxide-releasing nasal compositions and methods of use thereof Download PDF

Info

Publication number
CA3240044A1
CA3240044A1 CA3240044A CA3240044A CA3240044A1 CA 3240044 A1 CA3240044 A1 CA 3240044A1 CA 3240044 A CA3240044 A CA 3240044A CA 3240044 A CA3240044 A CA 3240044A CA 3240044 A1 CA3240044 A1 CA 3240044A1
Authority
CA
Canada
Prior art keywords
composition
buffer
sodium
berdazimer
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3240044A
Other languages
English (en)
French (fr)
Inventor
Daniel Albert Riccio
Carri Brodnax Geer
Benjamin Joseph Monroe Privett
Shaylyn Elizabeth Walter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LNHC Inc
Original Assignee
LNHC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LNHC Inc filed Critical LNHC Inc
Publication of CA3240044A1 publication Critical patent/CA3240044A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3240044A 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof Pending CA3240044A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163290928P 2021-12-17 2021-12-17
US63/290,928 2021-12-17
PCT/US2022/081754 WO2023114971A1 (en) 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof

Publications (1)

Publication Number Publication Date
CA3240044A1 true CA3240044A1 (en) 2023-06-22

Family

ID=86773604

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3240044A Pending CA3240044A1 (en) 2021-12-17 2022-12-16 Nitric oxide-releasing nasal compositions and methods of use thereof

Country Status (9)

Country Link
US (1) US20250049841A1 (enExample)
EP (1) EP4447946A4 (enExample)
JP (1) JP2024547022A (enExample)
KR (1) KR20240125633A (enExample)
CN (1) CN118742298A (enExample)
AU (1) AU2022409833A1 (enExample)
CA (1) CA3240044A1 (enExample)
IL (1) IL313526A (enExample)
WO (1) WO2023114971A1 (enExample)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1871433B1 (en) * 2005-03-24 2009-04-22 NOLabs AB Cosmetic treatment with nitric oxide, device for performing said treatment and manufacturing method therefor
EP1888510A4 (en) * 2005-05-27 2013-01-16 Univ North Carolina NITROGEN OXIDE-RELATED PARTICLES FOR NITROGEN OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS
WO2010044875A2 (en) * 2008-10-16 2010-04-22 Novan, Inc. Nitric oxide releasing particles for oral care applications
AU2015229626B2 (en) * 2014-03-14 2021-05-20 Sanotize Research And Development Corp. Treating diseases using nitric oxide releasing solutions
WO2016160089A1 (en) * 2015-03-27 2016-10-06 Novan, Inc. Topical antiviral compositions, delivery systems, and methods of using the same
EP3177262A4 (en) * 2014-08-08 2018-04-18 Novan Inc. Topical emulsions
US11166980B2 (en) * 2016-04-13 2021-11-09 Novan, Inc. Compositions, systems, kits, and methods for treating an infection
GB2599818B (en) * 2019-06-04 2024-01-31 Thirty Respiratory Ltd Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
CN112791096A (zh) * 2020-12-31 2021-05-14 南京诺令生物科技有限公司 一种可自提供一氧化氮的洗鼻盐及其应用

Also Published As

Publication number Publication date
EP4447946A4 (en) 2026-01-07
IL313526A (en) 2024-08-01
AU2022409833A1 (en) 2024-06-20
WO2023114971A1 (en) 2023-06-22
US20250049841A1 (en) 2025-02-13
EP4447946A1 (en) 2024-10-23
CN118742298A (zh) 2024-10-01
JP2024547022A (ja) 2024-12-26
KR20240125633A (ko) 2024-08-19

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