CA3231551A1 - Profilage predictif de resultats pour l'utilisation d'une molecule de liaison anti-semaphorine-4d pour traiter des troubles neurodegeneratifs - Google Patents
Profilage predictif de resultats pour l'utilisation d'une molecule de liaison anti-semaphorine-4d pour traiter des troubles neurodegeneratifs Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2505/00—Evaluating, monitoring or diagnosing in the context of a particular type of medical care
- A61B2505/09—Rehabilitation or training
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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Abstract
L'invention concerne des méthodes permettant de sélectionner des sujets présentant un trouble neurodégénératif pour le traitement avec une molécule de liaison isolée qui se lie de manière spécifique à la sémaphorine-4D (SEMA4D), une méthode pour prédire le résultat de traitement de sujets présentant un trouble neurodégénératif qui sont traités avec une molécule de liaison isolée qui se lie de manière spécifique à SEMA4D et des méthodes pour traiter des sujets présentant un trouble neurodégénératif avec une molécule de liaison isolée qui se lie de manière spécifique à SEMA4D.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2021/052142 WO2023048726A1 (fr) | 2021-09-27 | 2021-09-27 | Profilage prédictif de résultats pour l'utilisation d'une molécule de liaison anti-sémaphorine-4d pour traiter des troubles neurodégénératifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3231551A1 true CA3231551A1 (fr) | 2023-03-30 |
Family
ID=78463919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3231551A Pending CA3231551A1 (fr) | 2021-09-27 | 2021-09-27 | Profilage predictif de resultats pour l'utilisation d'une molecule de liaison anti-semaphorine-4d pour traiter des troubles neurodegeneratifs |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR20240063995A (fr) |
| AU (1) | AU2021465518A1 (fr) |
| CA (1) | CA3231551A1 (fr) |
| IL (1) | IL311639A (fr) |
| WO (1) | WO2023048726A1 (fr) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| AU633698B2 (en) | 1990-01-12 | 1993-02-04 | Amgen Fremont Inc. | Generation of xenogeneic antibodies |
| FR2686087A1 (fr) | 1992-01-13 | 1993-07-16 | Inst Nat Sante Rech Med | Nouvel antigene lymphocytaire, anticorps correspondant et leurs applications. |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US6849425B1 (en) | 1999-10-14 | 2005-02-01 | Ixsys, Inc. | Methods of optimizing antibody variable region binding affinity |
| JP4095753B2 (ja) | 2000-03-30 | 2008-06-04 | 株式会社ルネサステクノロジ | コンピュータ読み取り可能な記憶媒体、および半導体装置の設計方法 |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| EP1442749A1 (fr) | 2003-01-31 | 2004-08-04 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Utilisation d'un anticorps anti-CD100 pour le traitement et le diagnostic d'une maladie inflammatoire du système nerveux central |
| EP2069404B1 (fr) | 2007-02-14 | 2011-01-05 | Vaccinex, Inc. | Anticorps humanises anti-cd100 |
| US8496938B2 (en) | 2009-05-08 | 2013-07-30 | Vaccinex, Inc. | Anti-CD100 neutralizing neutralizing antibodies and methods of using the same |
| NZ630892A (en) * | 2013-10-21 | 2016-03-31 | Vaccinex Inc | Use of semaphorin-4d binding molecules for treating neurodegenerative disorders |
| KR102533921B1 (ko) * | 2017-02-22 | 2023-05-17 | 백시넥스 인코포레이티드 | 신경변성 또는 신경염증성 질환에서의 신경교세포 활성화의 조기 검출 |
| SG11201909466RA (en) | 2017-05-05 | 2019-11-28 | Vaccinex Inc | Human anti-semaphorin 4d antibody |
-
2021
- 2021-09-27 WO PCT/US2021/052142 patent/WO2023048726A1/fr active Application Filing
- 2021-09-27 IL IL311639A patent/IL311639A/en unknown
- 2021-09-27 KR KR1020247013488A patent/KR20240063995A/ko active Search and Examination
- 2021-09-27 AU AU2021465518A patent/AU2021465518A1/en active Pending
- 2021-09-27 CA CA3231551A patent/CA3231551A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021465518A1 (en) | 2024-05-02 |
| KR20240063995A (ko) | 2024-05-10 |
| IL311639A (en) | 2024-05-01 |
| WO2023048726A1 (fr) | 2023-03-30 |
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