CA3230928A1 - Procedes d'utilisation d'arn guides avec des modifications chimiques - Google Patents
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- CA3230928A1 CA3230928A1 CA3230928A CA3230928A CA3230928A1 CA 3230928 A1 CA3230928 A1 CA 3230928A1 CA 3230928 A CA3230928 A CA 3230928A CA 3230928 A CA3230928 A CA 3230928A CA 3230928 A1 CA3230928 A1 CA 3230928A1
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Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
L'invention concerne des compositions et des procédés pour induire une édition basée sur CRISPR/Cas d'un acide nucléique cible (par exemple, un ADN cible ou un ARN cible), ou moduler l'expression d'un acide nucléique cible, in vitro ou dans une cellule, à l'aide d'ARN guides modifiés (ARNg) qui intègrent un ou plusieurs nucléotides chimiquement modifiés. Dans certains aspects, ces ARNg modifiés offrent des performances supérieures dans des conditions difficiles.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163243985P | 2021-09-14 | 2021-09-14 | |
| US63/243,985 | 2021-09-14 | ||
| US63/339,737 | 2022-05-09 | ||
| PCT/US2022/043553 WO2023043856A1 (fr) | 2021-09-14 | 2022-09-14 | Procédés d'utilisation d'arn guides avec des modifications chimiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3230928A1 true CA3230928A1 (fr) | 2023-03-23 |
Family
ID=90124271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3230928A Pending CA3230928A1 (fr) | 2021-09-14 | 2022-09-14 | Procedes d'utilisation d'arn guides avec des modifications chimiques |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA3230928A1 (fr) |
-
2022
- 2022-09-14 CA CA3230928A patent/CA3230928A1/fr active Pending
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