CA3211079A1 - Compositions de derive de plaquettes lyophilisees pour le traitement de la coagulopathie induite par les plaquettes - Google Patents

Compositions de derive de plaquettes lyophilisees pour le traitement de la coagulopathie induite par les plaquettes Download PDF

Info

Publication number
CA3211079A1
CA3211079A1 CA3211079A CA3211079A CA3211079A1 CA 3211079 A1 CA3211079 A1 CA 3211079A1 CA 3211079 A CA3211079 A CA 3211079A CA 3211079 A CA3211079 A CA 3211079A CA 3211079 A1 CA3211079 A1 CA 3211079A1
Authority
CA
Canada
Prior art keywords
composition
subject
fdpds
platelets
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3211079A
Other languages
English (en)
Inventor
Keith Andrew MOSKOWITZ
Braden Carl Ishler
William Matthew Dickerson
Narendra Nath Tandon
Amber Nicole LEE
Stephen Edward AMOS
Rafael Jorda
Michael Alexander Mathews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellphire Inc
Original Assignee
Cellphire Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US17/673,773 external-priority patent/US20220168353A1/en
Application filed by Cellphire Inc filed Critical Cellphire Inc
Priority claimed from PCT/US2022/016866 external-priority patent/WO2022178177A1/fr
Publication of CA3211079A1 publication Critical patent/CA3211079A1/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des méthodes et des compositions pour traiter une coagulopathie chez un sujet. De telles méthodes peuvent comprendre l'administration au sujet en ayant besoin, par exemple parce qu'il a reçu un agent anticoagulant, une quantité efficace d'une composition comprenant des plaquettes, ou dans des modes de réalisation illustratifs, des dérivés de plaquettes, et dans d'autres modes de réalisation illustratifs, des dérivés de plaquettes lyophilisés (FDPD). L'invention concerne également diverses propriétés d'exemples de modes de réalisation de telles méthodes et de tels dérivés de plaquettes, ainsi que de nombreux aspects et modes de réalisation supplémentaires.
CA3211079A 2021-02-17 2022-02-17 Compositions de derive de plaquettes lyophilisees pour le traitement de la coagulopathie induite par les plaquettes Pending CA3211079A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163150338P 2021-02-17 2021-02-17
US63/150,338 2021-02-17
US202163275937P 2021-11-04 2021-11-04
US63/275,937 2021-11-04
US202163276420P 2021-11-05 2021-11-05
US63/276,420 2021-11-05
US202163264227P 2021-11-17 2021-11-17
US63/264,227 2021-11-17
US17/673,773 2022-02-16
US17/673,773 US20220168353A1 (en) 2019-08-16 2022-02-16 Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy
PCT/US2022/016866 WO2022178177A1 (fr) 2021-02-17 2022-02-17 Compositions de dérivé de plaquettes lyophilisées pour le traitement de la coagulopathie induite par les plaquettes

Publications (1)

Publication Number Publication Date
CA3211079A1 true CA3211079A1 (fr) 2022-08-25

Family

ID=87575366

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3211079A Pending CA3211079A1 (fr) 2021-02-17 2022-02-17 Compositions de derive de plaquettes lyophilisees pour le traitement de la coagulopathie induite par les plaquettes

Country Status (4)

Country Link
EP (1) EP4294411A1 (fr)
JP (1) JP2024507362A (fr)
AU (1) AU2022221719A1 (fr)
CA (1) CA3211079A1 (fr)

Also Published As

Publication number Publication date
EP4294411A1 (fr) 2023-12-27
AU2022221719A1 (en) 2023-08-24
JP2024507362A (ja) 2024-02-19

Similar Documents

Publication Publication Date Title
US20220168353A1 (en) Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy
US20220273724A1 (en) Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy
US20220279777A1 (en) Freeze-dried platelet derivative compositions for treating anticoagulant-induced coagulopathy
US11701388B2 (en) Thrombosomes as an antiplatelet agent reversal agent
WO2022178177A1 (fr) Compositions de dérivé de plaquettes lyophilisées pour le traitement de la coagulopathie induite par les plaquettes
WO2022178191A1 (fr) Compositions lyophilisées de dérivés de plaquettes pour le traitement de la coagulopathie induite par les anticoagulants
US11813572B2 (en) Materials and methods for producing blood products
AU2005272821B2 (en) Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
US20210046120A1 (en) Thrombosomes as an anticoagulant reversal agent
US20210308185A1 (en) Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets
US20200291356A1 (en) Canine blood platelet preparations
US20230149467A1 (en) Platelet derivative compositions, and methods of making and using such compositions
US20230112136A1 (en) Canine blood platelet preparations
WO2023081804A1 (fr) Compositions de dérivés de plaquettes et leurs méthodes de production et d'utilisation
CA3211079A1 (fr) Compositions de derive de plaquettes lyophilisees pour le traitement de la coagulopathie induite par les plaquettes
US20240066065A1 (en) Platelet derivatives for treating coagulopathy
US20240307453A1 (en) Methods for controlling bleeding in a subject afflicted with hermansky pudlak syndrome using platelet derivative compositions
WO2023220739A1 (fr) Compositions dérivées de plaquettes destinées à être utilisées chez des sujets atteints d'un syndrome de hermansky pudlak ou d'un syndrome de bernard soulier