CA3189482A1 - Recepteurs chimeriques anti-cd72 et utilisations de ceux-ci - Google Patents
Recepteurs chimeriques anti-cd72 et utilisations de ceux-ciInfo
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- CA3189482A1 CA3189482A1 CA3189482A CA3189482A CA3189482A1 CA 3189482 A1 CA3189482 A1 CA 3189482A1 CA 3189482 A CA3189482 A CA 3189482A CA 3189482 A CA3189482 A CA 3189482A CA 3189482 A1 CA3189482 A1 CA 3189482A1
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- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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Abstract
La présente invention concerne des compositions et des procédés comprenant des récepteurs antigéniques chimériques anti-CD72, des cellules hôtes modifiées pour inclure des molécules de récepteur antigénique chimérique anti-CD72. Les compositions, les procédés, et les utilisations selon l'invention incluent ceux pour des polythérapies impliquant l'administration d'un récepteur d'engloutissement chimérique ou d'un récepteur Tim chimérique, comme des cellules immunitaires modifiées pour co-exprimer à la fois le récepteur antigénique chimérique anti-CD72 et le récepteur d'engloutissement chimérique ou le récepteur Tim chimérique.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
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US202063066149P | 2020-08-14 | 2020-08-14 | |
US63/066,149 | 2020-08-14 | ||
US202163172057P | 2021-04-07 | 2021-04-07 | |
US63/172,057 | 2021-04-07 | ||
US202163226736P | 2021-07-28 | 2021-07-28 | |
US63/226,736 | 2021-07-28 | ||
PCT/US2021/046043 WO2022036287A1 (fr) | 2020-08-14 | 2021-08-13 | Récepteurs chimériques anti-cd72 et utilisations de ceux-ci |
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CA3189482A1 true CA3189482A1 (fr) | 2022-02-17 |
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CA3189482A Pending CA3189482A1 (fr) | 2020-08-14 | 2021-08-13 | Recepteurs chimeriques anti-cd72 et utilisations de ceux-ci |
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EP (1) | EP4196150A1 (fr) |
CA (1) | CA3189482A1 (fr) |
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- 2021-08-13 EP EP21777885.1A patent/EP4196150A1/fr active Pending
- 2021-08-13 CA CA3189482A patent/CA3189482A1/fr active Pending
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EP4196150A1 (fr) | 2023-06-21 |
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