CA3181389A1 - Rna markers and methods for identifying colon cell proliferative disorders - Google Patents
Rna markers and methods for identifying colon cell proliferative disordersInfo
- Publication number
- CA3181389A1 CA3181389A1 CA3181389A CA3181389A CA3181389A1 CA 3181389 A1 CA3181389 A1 CA 3181389A1 CA 3181389 A CA3181389 A CA 3181389A CA 3181389 A CA3181389 A CA 3181389A CA 3181389 A1 CA3181389 A1 CA 3181389A1
- Authority
- CA
- Canada
- Prior art keywords
- mir
- hsa
- mirna
- subject
- cell proliferative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
- G06N20/20—Ensemble learning
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medical Informatics (AREA)
- Data Mining & Analysis (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Theoretical Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Software Systems (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Evolutionary Computation (AREA)
- Artificial Intelligence (AREA)
- Biochemistry (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioethics (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Computing Systems (AREA)
- General Physics & Mathematics (AREA)
- Mathematical Physics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063017552P | 2020-04-29 | 2020-04-29 | |
| US63/017,552 | 2020-04-29 | ||
| US202063024875P | 2020-05-14 | 2020-05-14 | |
| US63/024,875 | 2020-05-14 | ||
| PCT/US2021/029361 WO2021222220A2 (en) | 2020-04-29 | 2021-04-27 | Rna markers and methods for identifying colon cell proliferative disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3181389A1 true CA3181389A1 (en) | 2021-11-04 |
Family
ID=78332157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3181389A Pending CA3181389A1 (en) | 2020-04-29 | 2021-04-27 | Rna markers and methods for identifying colon cell proliferative disorders |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230160019A1 (enExample) |
| EP (1) | EP4143309A4 (enExample) |
| JP (1) | JP2023524016A (enExample) |
| KR (1) | KR20230017206A (enExample) |
| CN (1) | CN115812101A (enExample) |
| AU (1) | AU2021263680A1 (enExample) |
| CA (1) | CA3181389A1 (enExample) |
| WO (1) | WO2021222220A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019060716A1 (en) | 2017-09-25 | 2019-03-28 | Freenome Holdings, Inc. | SAMPLE EXTRACTION METHODS AND SYSTEMS |
| KR20220015367A (ko) | 2019-05-31 | 2022-02-08 | 프리놈 홀딩스, 인크. | 메틸화된 핵산의 고심도 시퀀싱 방법 및 시스템 |
| AU2021245992A1 (en) | 2020-03-31 | 2022-11-10 | Freenome Holdings, Inc. | Methods and systems for detecting colorectal cancer via nucleic acid methylation analysis |
| CN116670510A (zh) | 2020-10-05 | 2023-08-29 | 福瑞诺姆控股公司 | 用于结肠细胞增殖性病症的早期检测的标志物 |
| CA3202255A1 (en) | 2020-12-21 | 2022-06-30 | Hayley WARSINSKE | Markers for the early detection of colon cell proliferative disorders |
| JP2025517309A (ja) | 2022-05-17 | 2025-06-05 | ガーダント ヘルス， インコーポレイテッド | 創薬可能な標的を特定するための方法およびがんを処置するための方法 |
| WO2024009221A1 (en) * | 2022-07-04 | 2024-01-11 | Artificial Intelligence Expert Srl | Method and system for multi-cancer management in subject |
| US11992318B2 (en) * | 2022-07-13 | 2024-05-28 | Celestin B. Bitjonck | Diagnostic lab-on-a-chip device |
| CN118048450A (zh) * | 2022-11-15 | 2024-05-17 | 杭州诺辉健康科技有限公司 | 使用miRNA亚型的家族占比检测癌症 |
| US12587274B2 (en) | 2023-03-28 | 2026-03-24 | Quantum Generative Materials Llc | Satellite optimization management system based on natural language input and artificial intelligence |
| US12368503B2 (en) | 2023-12-27 | 2025-07-22 | Quantum Generative Materials Llc | Intent-based satellite transmit management based on preexisting historical location and machine learning |
| US12603701B2 (en) | 2023-12-27 | 2026-04-14 | Quantum Generative Materials Llc | Distributed satellite constellation management and control system |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100010196A1 (en) * | 1997-09-26 | 2010-01-14 | Abt Holding Company | Compositions and methods for non-targeted activation of endogenous genes |
| US20040018973A1 (en) * | 2002-01-25 | 2004-01-29 | University Of Pittsburgh | Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof |
| NZ593226A (en) * | 2006-01-11 | 2012-10-26 | Genomic Health Inc | Gene expression markers (efnb2) for colorectal cancer prognosis |
| EP2336353A1 (en) * | 2009-12-17 | 2011-06-22 | febit holding GmbH | miRNA fingerprints in the diagnosis of diseases |
| JP2013526852A (ja) * | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| WO2011128900A2 (en) * | 2010-04-15 | 2011-10-20 | Hadasit Medical Research Services And Development Ltd. | Early detection and staging of colorectal cancer using a panel of micro rnas |
| US20120088687A1 (en) * | 2010-10-08 | 2012-04-12 | Baylor Research Institute | MicroRNAs (miRNA) as Biomarkers for the Identification of Familial and Non-Familial Colorectal Cancer |
| EP2718463B1 (en) * | 2011-06-08 | 2016-01-20 | Comprehensive Biomarker Center GmbH | Complex sets of mirnas as non-invasive biomarkers for dilated cardiomyopathy |
| US20160076098A1 (en) * | 2013-04-12 | 2016-03-17 | Drexel University | Methods of diagnosing and treating chronic pain |
| EP3256607B1 (en) * | 2015-02-13 | 2021-01-20 | Patel, Abhijit Ajit | Methods for highly parallel and accurate detection of nucleic acids |
| US10577645B2 (en) * | 2016-03-18 | 2020-03-03 | Norgen Biotek Corp. | Methods and kits for improving global gene expression analysis of human blood, plasma and/or serum derived RNA |
| ES3002715T3 (en) * | 2016-04-14 | 2025-03-07 | Guardant Health Inc | Methods for early detection of cancer |
| EP3571315B1 (en) * | 2017-01-23 | 2025-01-08 | Gatehouse Bio, Inc. | Methods for identifying and using small rna predictors |
| AU2018243360B2 (en) * | 2017-03-29 | 2023-10-26 | Cornell University | Devices, processes, and systems for determination of nucleic acid sequence, expression, copy number, or methylation changes using combined nuclease, ligase, polymerase, and sequencing reactions |
| JP7455757B2 (ja) * | 2018-04-13 | 2024-03-26 | フリーノーム・ホールディングス・インコーポレイテッド | 生体試料の多検体アッセイのための機械学習実装 |
-
2021
- 2021-04-27 JP JP2022565960A patent/JP2023524016A/ja active Pending
- 2021-04-27 CN CN202180046619.4A patent/CN115812101A/zh active Pending
- 2021-04-27 CA CA3181389A patent/CA3181389A1/en active Pending
- 2021-04-27 AU AU2021263680A patent/AU2021263680A1/en active Pending
- 2021-04-27 KR KR1020227041793A patent/KR20230017206A/ko active Pending
- 2021-04-27 WO PCT/US2021/029361 patent/WO2021222220A2/en not_active Ceased
- 2021-04-27 EP EP21796511.0A patent/EP4143309A4/en active Pending
-
2022
- 2022-10-26 US US18/049,785 patent/US20230160019A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4143309A2 (en) | 2023-03-08 |
| EP4143309A4 (en) | 2025-01-01 |
| JP2023524016A (ja) | 2023-06-08 |
| US20230160019A1 (en) | 2023-05-25 |
| WO2021222220A3 (en) | 2021-12-09 |
| CN115812101A (zh) | 2023-03-17 |
| WO2021222220A2 (en) | 2021-11-04 |
| KR20230017206A (ko) | 2023-02-03 |
| AU2021263680A1 (en) | 2022-11-24 |
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