CA3176108A1 - New use of angiotensin ii type 2 receptor agonist - Google Patents

New use of angiotensin ii type 2 receptor agonist

Info

Publication number
CA3176108A1
CA3176108A1 CA3176108A CA3176108A CA3176108A1 CA 3176108 A1 CA3176108 A1 CA 3176108A1 CA 3176108 A CA3176108 A CA 3176108A CA 3176108 A CA3176108 A CA 3176108A CA 3176108 A1 CA3176108 A1 CA 3176108A1
Authority
CA
Canada
Prior art keywords
respiratory
treatment
virus
compound
pharmaceutically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3176108A
Other languages
English (en)
French (fr)
Inventor
Carl-Johan Dalsgaard
Johan Raud
Rohit Batta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vicore Pharma AB
Original Assignee
Vicore Pharma AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2004209.9A external-priority patent/GB202004209D0/en
Priority claimed from GBGB2009574.1A external-priority patent/GB202009574D0/en
Application filed by Vicore Pharma AB filed Critical Vicore Pharma AB
Publication of CA3176108A1 publication Critical patent/CA3176108A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/215IFN-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA3176108A 2020-03-23 2021-03-22 New use of angiotensin ii type 2 receptor agonist Pending CA3176108A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB2004209.9A GB202004209D0 (en) 2020-03-23 2020-03-23 New use
GB2004209.9 2020-03-23
GB2009574.1 2020-06-23
GBGB2009574.1A GB202009574D0 (en) 2020-06-23 2020-06-23 New use
US17/113,416 US11123329B1 (en) 2020-03-23 2020-12-07 Use of angiotensin II type 2 receptor agonist
US17/113,416 2020-12-07
PCT/GB2021/050699 WO2021191592A1 (en) 2020-03-23 2021-03-22 New use of angiotensin ii type 2 receptor agonist

Publications (1)

Publication Number Publication Date
CA3176108A1 true CA3176108A1 (en) 2021-09-30

Family

ID=77747178

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3176108A Pending CA3176108A1 (en) 2020-03-23 2021-03-22 New use of angiotensin ii type 2 receptor agonist

Country Status (12)

Country Link
US (2) US11123329B1 (https=)
EP (1) EP4125881B1 (https=)
JP (1) JP7671305B2 (https=)
CN (1) CN115605201A (https=)
CA (1) CA3176108A1 (https=)
ES (1) ES2992423T3 (https=)
HR (1) HRP20241435T1 (https=)
HU (1) HUE068662T2 (https=)
PL (1) PL4125881T3 (https=)
RS (1) RS66072B1 (https=)
SM (1) SMT202400427T1 (https=)
WO (1) WO2021191592A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202004094D0 (en) * 2020-03-20 2020-05-06 Vicore Pharma Ab New compounds and uses
US20220233480A1 (en) * 2020-03-23 2022-07-28 Vicore Pharma Ab Use of angiotensin ii type 2 receptor agonist
AU2021258178A1 (en) * 2020-04-22 2022-11-17 Airway Therapeutics, Inc. Use of surfactant protein D to treat viral infections
US20240408065A1 (en) * 2021-09-30 2024-12-12 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Cyano compound, and preparation method therefor and use thereof
CN115583984A (zh) * 2022-01-11 2023-01-10 嘉兴安谛康生物科技有限公司 氮杂螺类化合物及其制备方法、药物组合物和用途
CN114948950A (zh) * 2022-01-19 2022-08-30 广州谷森制药有限公司 一种药物组合物及其抗病毒用途
WO2024153020A1 (zh) * 2023-01-16 2024-07-25 海南先声药业有限公司 抗病毒药物组合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1529697B (zh) 2001-05-31 2010-09-22 维科尔药物公司 用作血管紧张素ⅱ激动剂的三环化合物
EP1723962A1 (en) 2005-05-19 2006-11-22 IMBA-Institut für Molekulare Biotechnologie GmbH Use of inhibitors of the renin-angiotensin system for the treatment of lung injuries
EP3265082A1 (en) 2015-03-02 2018-01-10 Vicore Pharma AB Angiotensin ii receptor agonist for treating pulmonary fibrosis
GB201818164D0 (en) 2018-11-07 2018-12-19 Vicore Pharma Ab New composition

Also Published As

Publication number Publication date
ES2992423T3 (es) 2024-12-12
JP7671305B2 (ja) 2025-05-01
US11123329B1 (en) 2021-09-21
CN115605201A (zh) 2023-01-13
EP4125881A1 (en) 2023-02-08
JP2023520323A (ja) 2023-05-17
US20210386712A1 (en) 2021-12-16
EP4125881C0 (en) 2024-07-24
RS66072B1 (sr) 2024-11-29
SMT202400427T1 (it) 2024-11-15
HUE068662T2 (hu) 2025-01-28
PL4125881T3 (pl) 2024-12-02
US20210290596A1 (en) 2021-09-23
HRP20241435T1 (hr) 2024-12-20
WO2021191592A1 (en) 2021-09-30
EP4125881B1 (en) 2024-07-24

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