CA3144650A1 - Cxcr4 inhibitors and uses thereof - Google Patents

Cxcr4 inhibitors and uses thereof Download PDF

Info

Publication number
CA3144650A1
CA3144650A1 CA3144650A CA3144650A CA3144650A1 CA 3144650 A1 CA3144650 A1 CA 3144650A1 CA 3144650 A CA3144650 A CA 3144650A CA 3144650 A CA3144650 A CA 3144650A CA 3144650 A1 CA3144650 A1 CA 3144650A1
Authority
CA
Canada
Prior art keywords
compound
cancer
carcinoma
optionally substituted
nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3144650A
Other languages
English (en)
French (fr)
Inventor
Renato Skerlj
Elyse Marie Josee Bourque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
X4 Pharmaceuticals Inc
Original Assignee
X4 Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by X4 Pharmaceuticals Inc filed Critical X4 Pharmaceuticals Inc
Publication of CA3144650A1 publication Critical patent/CA3144650A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA3144650A 2019-06-26 2020-06-26 Cxcr4 inhibitors and uses thereof Pending CA3144650A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962867003P 2019-06-26 2019-06-26
US62/867,003 2019-06-26
PCT/US2020/039816 WO2020264292A1 (en) 2019-06-26 2020-06-26 Cxcr4 inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
CA3144650A1 true CA3144650A1 (en) 2020-12-30

Family

ID=74059964

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3144650A Pending CA3144650A1 (en) 2019-06-26 2020-06-26 Cxcr4 inhibitors and uses thereof

Country Status (5)

Country Link
EP (1) EP3990456A1 (de)
JP (1) JP2022538138A (de)
CN (1) CN114206869A (de)
CA (1) CA3144650A1 (de)
WO (1) WO2020264292A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05011353A (es) * 2003-04-22 2005-11-28 Anormed Inc Compuestos heterociclicos que se unen al receptor de quimiocina con eficacia mejorada.
US7501518B2 (en) * 2003-04-22 2009-03-10 Genzyme Corporation Methods of making 2,6-diaryl piperidine derivatives
ES2870920T3 (es) * 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
WO2017223229A1 (en) * 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof

Also Published As

Publication number Publication date
WO2020264292A1 (en) 2020-12-30
CN114206869A (zh) 2022-03-18
EP3990456A1 (de) 2022-05-04
JP2022538138A (ja) 2022-08-31

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