CA3120716A1 - Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis - Google Patents

Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis Download PDF

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Publication number
CA3120716A1
CA3120716A1 CA3120716A CA3120716A CA3120716A1 CA 3120716 A1 CA3120716 A1 CA 3120716A1 CA 3120716 A CA3120716 A CA 3120716A CA 3120716 A CA3120716 A CA 3120716A CA 3120716 A1 CA3120716 A1 CA 3120716A1
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class
data
data set
imbalanced
minority
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CA3120716A
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English (en)
French (fr)
Inventor
Yolanda HAGAR
Gargi DATTA
Leigh Alexander
Michael HINTERBERG
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Somalogic Operating Co Inc
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Somalogic Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/117—Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4866—Evaluating metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A61B5/4872—Body fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7221—Determining signal validity, reliability or quality
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Artificial Intelligence (AREA)
  • Physiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Cardiology (AREA)
  • Mathematical Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Obesity (AREA)
  • Fuzzy Systems (AREA)
  • Evolutionary Computation (AREA)
  • Vascular Medicine (AREA)
  • Mathematical Analysis (AREA)
  • Computational Mathematics (AREA)
  • Algebra (AREA)
  • Mathematical Optimization (AREA)
CA3120716A 2018-11-29 2019-11-21 Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis Pending CA3120716A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862773028P 2018-11-29 2018-11-29
US62/773,028 2018-11-29
US201862783733P 2018-12-21 2018-12-21
US62/783,733 2018-12-21
PCT/US2019/062561 WO2020112478A1 (en) 2018-11-29 2019-11-21 Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis

Publications (1)

Publication Number Publication Date
CA3120716A1 true CA3120716A1 (en) 2020-06-04

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CA3120716A Pending CA3120716A1 (en) 2018-11-29 2019-11-21 Methods for determining disease risk combining downsampling of class-imbalanced sets with survival analysis

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Country Link
US (1) US20220015714A1 (enExample)
EP (1) EP3886696A4 (enExample)
JP (2) JP7680950B2 (enExample)
KR (1) KR20210099605A (enExample)
CN (1) CN113271849B (enExample)
AU (1) AU2019385818B2 (enExample)
CA (1) CA3120716A1 (enExample)
IL (1) IL283467A (enExample)
SG (1) SG11202105063QA (enExample)
WO (1) WO2020112478A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
US11996201B2 (en) * 2021-03-04 2024-05-28 Abbott Laboratories Technology to automatically identify the most relevant health failure risk factors
JP7322918B2 (ja) * 2021-03-29 2023-08-08 横河電機株式会社 プログラム、情報処理装置、及び学習モデルの生成方法
KR102393367B1 (ko) 2021-11-15 2022-05-03 오브젠 주식회사 생존 분석 시스템 및 그 제어방법
KR102424884B1 (ko) 2021-11-18 2022-07-27 오브젠 주식회사 생존 데이터 정제 서버와 생존 데이터 분석 서버를 포함하는 시스템 및 그 제어방법
CN114548327A (zh) * 2022-04-27 2022-05-27 湖南工商大学 基于平衡子集的软件缺陷预测方法、系统、设备及介质
CN115114270B (zh) * 2022-06-14 2024-08-02 马上消费金融股份有限公司 数据降采样方法及装置、电子设备、计算机可读存储介质
KR102688743B1 (ko) * 2023-08-16 2024-07-26 렉스이노베이션 주식회사 분산 배터리의 soh에 기초하여 이상을 탐지하는 방법
US20250069754A1 (en) * 2023-08-22 2025-02-27 Elythea, Inc. Predicting risk of pregnancy-related complications using machine learning
CN121015165A (zh) * 2025-06-30 2025-11-28 延边大学 基于多模态特征融合的睡眠呼吸暂停识别方法

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US7982066B2 (en) * 2005-12-09 2011-07-19 Novalife, Inc. High protein supplement
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
AU2010328019A1 (en) * 2009-12-09 2012-06-28 Aviir, Inc. Biomarker assay for diagnosis and classification of cardiovascular disease
US20120269418A1 (en) * 2011-04-22 2012-10-25 Ge Global Research Analyzing the expression of biomarkers in cells with clusters
CN104573708A (zh) * 2014-12-19 2015-04-29 天津大学 组合降采样极限学习机
WO2017059022A1 (en) * 2015-09-30 2017-04-06 Inform Genomics, Inc. Systems and methods for predicting treatment-regiment-related outcomes
CN109906275B (zh) * 2016-06-08 2023-05-12 爱荷华大学研究基金会 检测心血管疾病易感性的组合物和方法
GB201614394D0 (en) * 2016-08-23 2016-10-05 Imp Innovations Ltd Method
EP3510173A4 (en) * 2016-09-07 2020-05-20 Veracyte, Inc. METHODS AND SYSTEMS FOR DETECTING COMMON INTERSTITIAL PNEUMONIA
ES2944613T3 (es) * 2017-02-02 2023-06-22 Brahms Gmbh proADM y/o histonas como marcadores indicadores de un acontecimiento adverso
AU2018100796A4 (en) * 2018-06-14 2018-07-19 Macau University Of Science And Technology A genetic feature identifying system and a search method for identifying features of genetic information

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Publication number Publication date
CN113271849A (zh) 2021-08-17
AU2019385818B2 (en) 2025-04-24
KR20210099605A (ko) 2021-08-12
JP7680950B2 (ja) 2025-05-21
WO2020112478A1 (en) 2020-06-04
CN113271849B (zh) 2024-08-30
AU2019385818A1 (en) 2021-07-08
JP2025061136A (ja) 2025-04-10
IL283467A (en) 2021-07-29
US20220015714A1 (en) 2022-01-20
EP3886696A4 (en) 2022-08-24
JP2022509835A (ja) 2022-01-24
EP3886696A1 (en) 2021-10-06
SG11202105063QA (en) 2021-06-29

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