CA3120103A1 - Compositions de fusosome pour administration a des lymphocytes t - Google Patents
Compositions de fusosome pour administration a des lymphocytes t Download PDFInfo
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- CA3120103A1 CA3120103A1 CA3120103A CA3120103A CA3120103A1 CA 3120103 A1 CA3120103 A1 CA 3120103A1 CA 3120103 A CA3120103 A CA 3120103A CA 3120103 A CA3120103 A CA 3120103A CA 3120103 A1 CA3120103 A1 CA 3120103A1
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- fusosome
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- fusogen
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Abstract
La présente invention concerne, au moins en partie, des procédés et des compositions pour une administration de fusosomes in vivo. Dans certains modes de réalisation, le fusosome comprend une combinaison d'éléments qui favorisent la spécificité pour des cellules cibles, par exemple, un ou plusieurs éléments parmi un fusogène, un élément régulateur spécifique d'une cellule cible positive et un élément régulateur spécifique d'une cellule non cible. Dans certains modes de réalisation, le fusosome comprend une ou plusieurs modifications qui diminuent une réponse immunitaire contre le fusosome.
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US201862767320P | 2018-11-14 | 2018-11-14 | |
US62/767,320 | 2018-11-14 | ||
US62/900,053 | 2019-09-13 | ||
PCT/US2019/061434 WO2020102503A2 (fr) | 2018-11-14 | 2019-11-14 | Compositions de fusosome pour administration à des lymphocytes t |
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CA3120103A1 true CA3120103A1 (fr) | 2020-05-22 |
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Cited By (6)
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CN111909961A (zh) * | 2020-08-21 | 2020-11-10 | 华侨大学 | 一种CRISPR/Cas介导的ATL细胞基因编辑载体及其应用 |
CN113975299A (zh) * | 2020-07-27 | 2022-01-28 | 上海市公共卫生临床中心 | 利用呼吸道上皮细胞膜防治呼吸道传染病的方法及应用 |
CN114045306A (zh) * | 2021-11-10 | 2022-02-15 | 上海市食品药品检验研究院 | 一种反映免疫突触相关信号蛋白的荧光素酶互补系统质粒和稳转细胞株及其应用 |
CN115850482A (zh) * | 2022-09-26 | 2023-03-28 | 北京华正博研科技有限公司 | 含有干细胞外泌体的皮肤光老化修复产品 |
CN117467765A (zh) * | 2023-10-31 | 2024-01-30 | 西南医科大学附属口腔医院 | Fgf6在口腔黏膜癌变诊断、治疗中的应用 |
CN117487737A (zh) * | 2023-12-26 | 2024-02-02 | 汕头大学 | 一种含Fe3O4纳米颗粒的去核细胞及其制备与在抗衰老中的应用 |
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2019
- 2019-11-14 CA CA3120103A patent/CA3120103A1/fr active Pending
Cited By (9)
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CN113975299A (zh) * | 2020-07-27 | 2022-01-28 | 上海市公共卫生临床中心 | 利用呼吸道上皮细胞膜防治呼吸道传染病的方法及应用 |
CN111909961A (zh) * | 2020-08-21 | 2020-11-10 | 华侨大学 | 一种CRISPR/Cas介导的ATL细胞基因编辑载体及其应用 |
CN111909961B (zh) * | 2020-08-21 | 2022-04-19 | 华侨大学 | 一种CRISPR/Cas介导的ATL细胞基因编辑载体及其应用 |
CN114045306A (zh) * | 2021-11-10 | 2022-02-15 | 上海市食品药品检验研究院 | 一种反映免疫突触相关信号蛋白的荧光素酶互补系统质粒和稳转细胞株及其应用 |
CN114045306B (zh) * | 2021-11-10 | 2024-03-19 | 上海市食品药品检验研究院 | 一种反映免疫突触相关信号蛋白的荧光素酶互补系统质粒和稳转细胞株及其应用 |
CN115850482A (zh) * | 2022-09-26 | 2023-03-28 | 北京华正博研科技有限公司 | 含有干细胞外泌体的皮肤光老化修复产品 |
CN117467765A (zh) * | 2023-10-31 | 2024-01-30 | 西南医科大学附属口腔医院 | Fgf6在口腔黏膜癌变诊断、治疗中的应用 |
CN117487737A (zh) * | 2023-12-26 | 2024-02-02 | 汕头大学 | 一种含Fe3O4纳米颗粒的去核细胞及其制备与在抗衰老中的应用 |
CN117487737B (zh) * | 2023-12-26 | 2024-04-12 | 汕头大学 | 一种含Fe3O4纳米颗粒的去核细胞及其制备与在抗衰老中的应用 |
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