CA3116712A1 - Systemes et procedes de recherche et de traitement du cancer bases sur des donnees - Google Patents

Systemes et procedes de recherche et de traitement du cancer bases sur des donnees Download PDF

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Publication number
CA3116712A1
CA3116712A1 CA3116712A CA3116712A CA3116712A1 CA 3116712 A1 CA3116712 A1 CA 3116712A1 CA 3116712 A CA3116712 A CA 3116712A CA 3116712 A CA3116712 A CA 3116712A CA 3116712 A1 CA3116712 A1 CA 3116712A1
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CA
Canada
Prior art keywords
data
sequencing
database
cancer
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3116712A
Other languages
English (en)
Inventor
Shane Colley
Isaiah SIMPSON
Brian Reuter
Robert Tell
Hunter Lane
Kevin White
Nike BEAUBIER
Stephen Bush
Aly KHAN
Denise LAU
Kaanan Shah
Eric Lefkofsky
Hailey LEFKOFSKY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tempus Labs Inc
Original Assignee
Tempus Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tempus Labs Inc filed Critical Tempus Labs Inc
Publication of CA3116712A1 publication Critical patent/CA3116712A1/fr
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H15/00ICT specially adapted for medical reports, e.g. generation or transmission thereof
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Primary Health Care (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Databases & Information Systems (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)

Abstract

L'invention concerne un procédé et un système pour effectuer un séquençage génomique, le procédé comprenant le stockage d'un ensemble de programmes d'application d'utilisateur, chacun des programmes nécessitant un sous-ensemble spécifique d'application de données, pour chacun d'une pluralité de patients qui ont des cellules cancéreuses et qui reçoivent un traitement contre le cancer, l'obtention de données de dossiers cliniques dans des formes d'origine comprenant des informations d'état de cancer, des types de traitement et des informations d'efficacité de traitement, le stockage des données de dossiers cliniques dans une première base de données semi-structurée, pour chaque patient, à l'aide d'un séquenceur génomique pour générer des données de séquençage génomique pour les cellules cancéreuses et les cellules normales du patient, le stockage des données de séquençage dans la première base de données, la mise en forme au moins d'un sous-ensemble des premières données de base de données afin de générer des données structurées de système comprenant des données de dossier clinique et des données de séquençage, les données structurées de système étant optimisées pour la recherche, le stockage des données structurées de système dans une deuxième base de données, pour chaque programme d'application d'utilisateur, la sélection du sous-ensemble spécifique d'application de données à partir de la deuxième base de données et le stockage du sous-ensemble spécifique d'application de données dans une structure optimisée pour une interface de programme d'application dans une troisième base de données.
CA3116712A 2018-10-17 2019-10-17 Systemes et procedes de recherche et de traitement du cancer bases sur des donnees Pending CA3116712A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862746997P 2018-10-17 2018-10-17
US62/746,997 2018-10-17
PCT/US2019/056713 WO2020081795A1 (fr) 2018-10-17 2019-10-17 Systèmes et procédés de recherche et de traitement du cancer basés sur des données

Publications (1)

Publication Number Publication Date
CA3116712A1 true CA3116712A1 (fr) 2020-04-23

Family

ID=70284254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3116712A Pending CA3116712A1 (fr) 2018-10-17 2019-10-17 Systemes et procedes de recherche et de traitement du cancer bases sur des donnees

Country Status (3)

Country Link
AU (1) AU2019359878A1 (fr)
CA (1) CA3116712A1 (fr)
WO (1) WO2020081795A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023150285A1 (fr) * 2022-02-04 2023-08-10 Elixirgen Therapeutics, Inc. Systèmes et méthodes de protocole de thérapie cellulaire

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111816315B (zh) * 2020-05-28 2023-10-13 上海市生物医药技术研究院 胰腺导管癌状态评估模型构建方法及应用
CN116114032A (zh) * 2020-06-04 2023-05-12 爱克库尔斯公司 使用多级贝叶斯模型的用于精确肿瘤学的方法和系统

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2245198A1 (fr) * 2008-02-04 2010-11-03 Massachusetts Institute of Technology Sélection d'acides nucléiques par hybridation en solution en amorces oligonucléotidiques
US20150324527A1 (en) * 2013-03-15 2015-11-12 Northrop Grumman Systems Corporation Learning health systems and methods
US20140365242A1 (en) * 2013-06-07 2014-12-11 Siemens Medical Solutions Usa, Inc. Integration of Multiple Input Data Streams to Create Structured Data
US10642854B2 (en) 2016-10-07 2020-05-05 Sudeep Pattnaik Clinical data aggregation architecture and platform

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023150285A1 (fr) * 2022-02-04 2023-08-10 Elixirgen Therapeutics, Inc. Systèmes et méthodes de protocole de thérapie cellulaire

Also Published As

Publication number Publication date
AU2019359878A1 (en) 2021-05-27
WO2020081795A8 (fr) 2020-07-09
WO2020081795A1 (fr) 2020-04-23

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