CA3092917A1 - Antimicrobial quick kill film - Google Patents
Antimicrobial quick kill film Download PDFInfo
- Publication number
- CA3092917A1 CA3092917A1 CA3092917A CA3092917A CA3092917A1 CA 3092917 A1 CA3092917 A1 CA 3092917A1 CA 3092917 A CA3092917 A CA 3092917A CA 3092917 A CA3092917 A CA 3092917A CA 3092917 A1 CA3092917 A1 CA 3092917A1
- Authority
- CA
- Canada
- Prior art keywords
- antimicrobial
- film
- polymers
- peg
- eva
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/60—Additives non-macromolecular
- C09D7/63—Additives non-macromolecular organic
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
- C08K5/0058—Biocides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/17—Amines; Quaternary ammonium compounds
- C08K5/19—Quaternary ammonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Plant Pathology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The purpose of the invention is preventing the spread of bacteria and infectious disease by preparing a polymeric film with immediate bactericidal properties. In this invention, an antimicrobial agent is stored in a carrier which can regulate the antimicrobial agent release rate from an hour to several months. It should be noted that the antimicrobial properties of the film produced in this invention are customizable. This product can be used in the health-care facilities as smart coatings to prevent the transmission of microbes/ infections to every individual by direct and indirect contact. Moreover, it can be used as a smart covers in public areas and public transportation.
Description
Antimicrobial Quick Kill Film Technical field:
The technical field of this invention is related to medical, public healthcare products and health care facilities.
Technical issue:
Nowadays, given increasing trend of infections, there is an urgent need to antibacterial agents and films. For example, about 2 million people in the United States suffer from illnesses associated with nosocomial infections, of which around 900,000 people die each year.
In recent years, common additives such as ceramic nanoparticles, metal nanoparticles, silver nanoparticles, iron oxide nanoparticles, zinc oxide nanoparticles, titanium dioxide, magnesium oxide, and copper oxide are used to prepare antimicrobial films and coatings.
Antimicrobial coatings and films available on the market have a killing time over 24 hours.
Therefore, they are not able to use in infected areas because they cannot kill bacteria and germs immediately.
Antimicrobial additives such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, or a combination of these additives have immediate effect (under 24 hours) on bacteria. Usually these additives are used in gels and sprays and antiseptic tissues and so far these additives have not been used to produce antimicrobial films with self-antiseptics surface.
Prior arts:
= WO 2014/001541 is an invention related to an antimicrobial package suitable for containing materials which are susceptible to microbial growth or spoilage. In particular, the invention relates to an antimicrobial package for food and drink products = WO 2006/000032 refers to an antimicrobial polymeric package in which an antimicrobial additive has been used. This invention can be used in food packaging. In this invention, the polymeric materials are ethylene vinyl acetate (EVA), low-density polyethylene (PE), polyethylene glycol oil (PEG) and volatile antimicrobial oils.
Previous inventions dealt with food and fruit packaging, aimed at preventing entry of essential nutrients for bacterial growth, which ultimately leads to prolonging life span of the package content. It should be noted that market's available films with antimicrobial properties do not have the ability to remove bacteria instantaneously and immediately. They are used only for food and fruit packaging. Up to this time, an anti-microbial film with the aim of killing bacteria in a fraction of second has not been produced.
The technical field of this invention is related to medical, public healthcare products and health care facilities.
Technical issue:
Nowadays, given increasing trend of infections, there is an urgent need to antibacterial agents and films. For example, about 2 million people in the United States suffer from illnesses associated with nosocomial infections, of which around 900,000 people die each year.
In recent years, common additives such as ceramic nanoparticles, metal nanoparticles, silver nanoparticles, iron oxide nanoparticles, zinc oxide nanoparticles, titanium dioxide, magnesium oxide, and copper oxide are used to prepare antimicrobial films and coatings.
Antimicrobial coatings and films available on the market have a killing time over 24 hours.
Therefore, they are not able to use in infected areas because they cannot kill bacteria and germs immediately.
Antimicrobial additives such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, or a combination of these additives have immediate effect (under 24 hours) on bacteria. Usually these additives are used in gels and sprays and antiseptic tissues and so far these additives have not been used to produce antimicrobial films with self-antiseptics surface.
Prior arts:
= WO 2014/001541 is an invention related to an antimicrobial package suitable for containing materials which are susceptible to microbial growth or spoilage. In particular, the invention relates to an antimicrobial package for food and drink products = WO 2006/000032 refers to an antimicrobial polymeric package in which an antimicrobial additive has been used. This invention can be used in food packaging. In this invention, the polymeric materials are ethylene vinyl acetate (EVA), low-density polyethylene (PE), polyethylene glycol oil (PEG) and volatile antimicrobial oils.
Previous inventions dealt with food and fruit packaging, aimed at preventing entry of essential nutrients for bacterial growth, which ultimately leads to prolonging life span of the package content. It should be noted that market's available films with antimicrobial properties do not have the ability to remove bacteria instantaneously and immediately. They are used only for food and fruit packaging. Up to this time, an anti-microbial film with the aim of killing bacteria in a fraction of second has not been produced.
2 Description of the invention:
The purpose of the invention is preventing the spread of bacteria and infectious disease by preparing a polymeric film with immediate bactericidal properties. In this invention, an antimicrobial agent is stored in a carrier which can regulate the antimicrobial agent release rate from an hour to several months. It should be noted that the antimicrobial properties of the film produced in this invention are customizable. This product can be used in the health-care facilities as smart coatings to prevent the transmission of microbes/ infections to every individual by direct and indirect contact. Moreover, it can be used as a smart covers in public areas and public transportation.
In the present invention, polymers such as ethylene-based polymers (high-density polyethylene (HDPE) , low density polyethylene (LDPE), linear low density polyethylene (LLDPE) ), polypropylene (PP), polyamide (PA), polystyrene (PS), Polyethylene terephthalate (PET), polyvinyl chloride (PVC), Ethylene vinyl acetate (EVA) (8%, 18%, 28%, 38%) and natural polymers such as starch, poly lactic acid (PLA), natural rubber (NR) and Acrylonitrile butadiene rubber (NBR), or a combination of one or more polymers by percentages 5% to 50% can be used for the preparation of the antimicrobial films.
All films contain one or more carriers that hold antimicrobial agents, polymer's-compatible oils such as polyethylene glycol (PEG) with a molecular weight varies from 300 g /
mole to 10,000,000 g! mole, Polypropylene glycol (PPG), Dioctyl phthalate (DOP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP) with a composition of 1% to 30%.
Moreover, antimicrobial agents such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, with the composition of 0.01% to 20% can be used. Based on the type of the polymer oil and antimicrobial agents, the effective film performance time range can be tuned.
In support of this claim, the polymers that were used to prepare the films for this invention were LLDPE / EVA/ Oil with the volume fraction of (70%/28%/2%), respectively. The combination of PEG 400 and 4000 with the volume fraction of 50%/50% were used as an antimicrobial carrier and benzalkonium chloride was used as antimicrobial agent with the volume fraction of 0.13%.
It should be noted that the films prepared by combining different percentages of polymers LLDPE / EVA / Oil ( 90%-60%/10%-40%/ 1%-20%) and PEG as carrier material alone with a molecular mass of 300 g /Mole up to 10,000g / mole with a composition of 1% -30% of PEG or a combination of them with different molecular weights ranging from 300 g!
mole to 10,000 g!
mole with a composition of 1% -30% and benzalkonium chloride as an antimicrobial agent with a composition of 0.01% 20% is within the scope of this invention.
The purpose of the invention is preventing the spread of bacteria and infectious disease by preparing a polymeric film with immediate bactericidal properties. In this invention, an antimicrobial agent is stored in a carrier which can regulate the antimicrobial agent release rate from an hour to several months. It should be noted that the antimicrobial properties of the film produced in this invention are customizable. This product can be used in the health-care facilities as smart coatings to prevent the transmission of microbes/ infections to every individual by direct and indirect contact. Moreover, it can be used as a smart covers in public areas and public transportation.
In the present invention, polymers such as ethylene-based polymers (high-density polyethylene (HDPE) , low density polyethylene (LDPE), linear low density polyethylene (LLDPE) ), polypropylene (PP), polyamide (PA), polystyrene (PS), Polyethylene terephthalate (PET), polyvinyl chloride (PVC), Ethylene vinyl acetate (EVA) (8%, 18%, 28%, 38%) and natural polymers such as starch, poly lactic acid (PLA), natural rubber (NR) and Acrylonitrile butadiene rubber (NBR), or a combination of one or more polymers by percentages 5% to 50% can be used for the preparation of the antimicrobial films.
All films contain one or more carriers that hold antimicrobial agents, polymer's-compatible oils such as polyethylene glycol (PEG) with a molecular weight varies from 300 g /
mole to 10,000,000 g! mole, Polypropylene glycol (PPG), Dioctyl phthalate (DOP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP) with a composition of 1% to 30%.
Moreover, antimicrobial agents such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, with the composition of 0.01% to 20% can be used. Based on the type of the polymer oil and antimicrobial agents, the effective film performance time range can be tuned.
In support of this claim, the polymers that were used to prepare the films for this invention were LLDPE / EVA/ Oil with the volume fraction of (70%/28%/2%), respectively. The combination of PEG 400 and 4000 with the volume fraction of 50%/50% were used as an antimicrobial carrier and benzalkonium chloride was used as antimicrobial agent with the volume fraction of 0.13%.
It should be noted that the films prepared by combining different percentages of polymers LLDPE / EVA / Oil ( 90%-60%/10%-40%/ 1%-20%) and PEG as carrier material alone with a molecular mass of 300 g /Mole up to 10,000g / mole with a composition of 1% -30% of PEG or a combination of them with different molecular weights ranging from 300 g!
mole to 10,000 g!
mole with a composition of 1% -30% and benzalkonium chloride as an antimicrobial agent with a composition of 0.01% 20% is within the scope of this invention.
3 After preparing different specimens, antimicrobial activity of the films was investigated. E.coli bacteria with the concentration of 106 x 1.5 CFU / ml was prepared. 100 pl of fluid was contacted for 24 hours before inoculation with the sample. After culturing the medium for 8 hours, according to the optical density method, each sample series was evaluated using three biological replications at 600 nm wavelength. The results of microbial tests taken at different time intervals from films prepared with different composition percentages showed that 98.9% of bacteria were killed.
In addition, Performance repeatability of the films was tested by the Luminometer device with the general swab. The dirty object was rubbed several times with specific intervals on the armchair covered with the antimicrobial film and on the armchair without the antimicrobial film.
The results show that the covered-armchair is in the sterile range after rubbing the dirty object.
To prepare the samples, PEG and benzalkonium chloride were first mixed together in a dry blender, then EVA was added and then LLDPE was added to the final blend in a dry blender.
Finally, the final blend was processed in a twin screw extruder. Finally, a film blowing machine was used to make smart films. The temperature range was applied to all the machines has been set between 135-140 C.
Advantages of the invention:
= The absence of antimicrobial film with instantaneous killing action.
= Reduce the necessary time to wash or clean the surface = Cost-effectiveness = There is no need to clean surfaces with detergents over time = Production of various antimicrobial smart films with complex shapes and dimensions = Production of antimicrobial smart films with the potential of tuning and adjusting the release of effective antimicrobial agents A practical approach to invention implementation:
The film produced in this invention can be used in disposable and multi-use applications in various industries and locations. Generally, the user should choose the appropriate film based on the sensitivity of the desired location. Generally, based on the type of film, the user must, at the beginning of each shift (or based on the time period written on the film) , according to different places, the consumer should covers the desired location and then depending on the determined time collects the film covers and replaced them with the new covers.
(according to the place the films are consumed, they can be in the different forms such as rolled-films, pre-shaped films, shrink films and etc.) Briefly, some of the applications of this film are as follow.
In addition, Performance repeatability of the films was tested by the Luminometer device with the general swab. The dirty object was rubbed several times with specific intervals on the armchair covered with the antimicrobial film and on the armchair without the antimicrobial film.
The results show that the covered-armchair is in the sterile range after rubbing the dirty object.
To prepare the samples, PEG and benzalkonium chloride were first mixed together in a dry blender, then EVA was added and then LLDPE was added to the final blend in a dry blender.
Finally, the final blend was processed in a twin screw extruder. Finally, a film blowing machine was used to make smart films. The temperature range was applied to all the machines has been set between 135-140 C.
Advantages of the invention:
= The absence of antimicrobial film with instantaneous killing action.
= Reduce the necessary time to wash or clean the surface = Cost-effectiveness = There is no need to clean surfaces with detergents over time = Production of various antimicrobial smart films with complex shapes and dimensions = Production of antimicrobial smart films with the potential of tuning and adjusting the release of effective antimicrobial agents A practical approach to invention implementation:
The film produced in this invention can be used in disposable and multi-use applications in various industries and locations. Generally, the user should choose the appropriate film based on the sensitivity of the desired location. Generally, based on the type of film, the user must, at the beginning of each shift (or based on the time period written on the film) , according to different places, the consumer should covers the desired location and then depending on the determined time collects the film covers and replaced them with the new covers.
(according to the place the films are consumed, they can be in the different forms such as rolled-films, pre-shaped films, shrink films and etc.) Briefly, some of the applications of this film are as follow.
4 For example, in the hospital, the film can be stretched over on the seating chairs in waiting rooms, beds, hospitals equipment that are frequently touched by patientsõ
nurses, doctors, medical specialists and health care facilities, etc. It can be used in public transportation, for example, subway and bus handles and escalator handles. In educational centers, for example, it can be wrapped up in a kindergarten on a children's playground, on children's play toys such as chute, swings and so on.
Explicit industrial application of invention = The medical and dental industry = Medical and dental equipment industry = Healthcare equipment industry = Public Transportation Equipment Industry = The retail industry = Educational Centers = Public area
nurses, doctors, medical specialists and health care facilities, etc. It can be used in public transportation, for example, subway and bus handles and escalator handles. In educational centers, for example, it can be wrapped up in a kindergarten on a children's playground, on children's play toys such as chute, swings and so on.
Explicit industrial application of invention = The medical and dental industry = Medical and dental equipment industry = Healthcare equipment industry = Public Transportation Equipment Industry = The retail industry = Educational Centers = Public area
Claims (14)
1. Antimicrobial quick kill film which is consisted of following components:
a. LLDPE / EVA Polymers b. PEG
c. Benzalkonium chloride
a. LLDPE / EVA Polymers b. PEG
c. Benzalkonium chloride
2. According to claim 1, the percentage of LLDPE / EVA / Oil polymers in antimicrobial quick kill film ranges 70%/28%/2%.
3. According to claim 1, PEG has molecular weights 400 and 4000 with the volume fraction of 50%/50%.
4. According to claim 1, benzalkonium chloride is added with the volume fraction of 0.13%.
5. According to claim 1, the film has different percentages of LLDPE / EVA /
Oil polymers, about 90%-10% / 10%-90% / 1% - 30%.
Oil polymers, about 90%-10% / 10%-90% / 1% - 30%.
6. According to claim 3, PEG can be used alone or in a combination with a molecular mass of 300 g /Mole up to 10,000,000g with a composition of 1% - 30%.
7. According to claim 4, benzalkonium chloride has composition of 0.01% -20%.
8. To prepare an antimicrobial quick kill film, PEG and benzalkonium chloride are first mixed in a dry blender.
9. According to claim 8, subsequently, EVA and LLDPE are added into the final blend in the dry blender, respectively.
10. According to claims 7 and 8, next, the final blend is processed in Twin screw extruder
11. According to claims 7, 8, 9 and 10, finally, a film blowing machine is used to provide smart films at temperatures between 135-140 ° C.
12. According to claim 1, in the present invention, for the preparation of the antimicrobial films polymers such as ethylene-based polymers (high-density polyethylene (HDPE), low density polyethylene (LDPE), linear low density polyethylene (LLDPE) ), polypropylene (PP), polyamide (PA), polystyrene (PS), Polyethylene terephthalate (PET), polyvinyl chloride (PVC), Ethylene vinyl acetate (EVA) (8%, 18%, 28%, 38%) and natural polymers such as starch, poly lactic acid (PLA), natural rubber (NR) and Acrylonitrile butadiene rubber (NBR), or a combination of one or more polymers by percentages 5% to 50% can be used.
13. According to claim 12, all films contain one or more carriers that hold antimicrobial agents, polymer's-compatible oils such as polyethylene glycol (PEG) with a molecular weight varies from 300 g / mol to 10,000,000 g / mol, Polypropylene glycol (PPG), Dioctyl phthalate (DOP), diisodecyl phthalate (DIDP), diisononyl phthalate (DINP), with a composition of 1% to 30%.
14. According to claim 1, antimicrobial agents such as ethanol, isopropanol, chlorhexidine, propyl alcohol, benzalkonium chloride, peracetic acid, hydrogen peroxide, Didecyldimethylammonium chloride, Polyhexamethylene Biguanide Hydrochloride, chlorhexidine gluconate, alkyl dimethyl benzyl ammonium chloride, Sodium hypochlorite, iodine, 70% alcohol, glutaraldehyde, Sodium iodide and chloramine T, with the composition of 0.01% to 20% can be used.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2019/050251 WO2020144495A1 (en) | 2019-01-13 | 2019-01-13 | Antimicrobial quick kill film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3092917A1 true CA3092917A1 (en) | 2020-07-16 |
Family
ID=71520921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3092917A Pending CA3092917A1 (en) | 2019-01-13 | 2019-01-13 | Antimicrobial quick kill film |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA3092917A1 (en) |
| WO (1) | WO2020144495A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1773130A4 (en) * | 2004-06-29 | 2008-09-03 | Univ Victoria | Antimicrobial packaging material |
| EP2649878A1 (en) * | 2010-04-14 | 2013-10-16 | Avery Dennison Corporation | Methods for increasing effectiveness of antimicrobial agents in polymeric films |
-
2019
- 2019-01-13 CA CA3092917A patent/CA3092917A1/en active Pending
- 2019-01-13 WO PCT/IB2019/050251 patent/WO2020144495A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020144495A1 (en) | 2020-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Penna et al. | The efficacy of chemical agents in cleaning and disinfection programs | |
| US11717533B2 (en) | Zinc composition and their use in anti-microbial applications | |
| Kampf | Adaptive bacterial response to low level chlorhexidine exposure and its implications for hand hygiene | |
| Patwardhan et al. | Disinfection, sterilization and operation theater guidelines for dermatosurgical practitioners in India | |
| Nostro et al. | Effect of temperature on the release of carvacrol and cinnamaldehyde incorporated into polymeric systems to control growth and biofilms of Escherichia coli and Staphylococcus aureus | |
| KR102100359B1 (en) | Method for preparing natural antimicrobial composition comprising fermentated plum and natural antimicrobial composition prepared by the same | |
| Barza | Efficacy and tolerability of ClO2-generating gloves | |
| US9833471B1 (en) | Hypochlorous acid-based hand sanitizer | |
| Kampf et al. | Chlorhexidine digluconate | |
| CN104173248A (en) | Natural plant essential oil-containing disinfecting liquid soap, as well as preparation method and application thereof | |
| CN102846717A (en) | Disposable hand disinfection wet wipe | |
| Oranusi et al. | Assessment of microbial quality and antibacterial activity of commonly used hand washes | |
| Spooner | Hazards associated with the microbiological contamination of cosmetics, toiletries and non-sterile pharmaceuticals | |
| CA3092917A1 (en) | Antimicrobial quick kill film | |
| Ibegbulam-Njoku et al. | Microbiological evaluation of cosmetics products sourced in Aba city, Nigeria | |
| JP6310745B2 (en) | Bactericidal composition | |
| CN105010390A (en) | Highly-effective clothing disinfectant | |
| CN104523748A (en) | Compound iodine disinfectant and preparation method and application thereof | |
| CN109016762A (en) | Antibacterial plastic film and its application | |
| CN105873443A (en) | Antimicrobial compositions containing low concentrations of food allowed organic acids and amine oxide amphoteric surfactants | |
| Art | Combination povidone-iodine and alcohol formulations more effective, more convenient versus formulations containing either iodine or alcohol alone: a review of the literature | |
| US20170303539A1 (en) | Antimicrobial Compositions And Uses Thereof | |
| Favero | Products containing biocides: perceptions and realities | |
| CN106577807A (en) | Fragrant bactericide | |
| KR20040096930A (en) | Nano silver carton rubber gloves |