CA3079477A1 - Amplicon region as epigenetic marker for the identification of non-classical monocytes - Google Patents

Amplicon region as epigenetic marker for the identification of non-classical monocytes Download PDF

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Publication number
CA3079477A1
CA3079477A1 CA3079477A CA3079477A CA3079477A1 CA 3079477 A1 CA3079477 A1 CA 3079477A1 CA 3079477 A CA3079477 A CA 3079477A CA 3079477 A CA3079477 A CA 3079477A CA 3079477 A1 CA3079477 A1 CA 3079477A1
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CA
Canada
Prior art keywords
amplicon
cells
seq
classical
methylation
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3079477A
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English (en)
French (fr)
Inventor
Sven Olek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precision for Medicine GmbH
Original Assignee
Epiontis GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Epiontis GmbH filed Critical Epiontis GmbH
Publication of CA3079477A1 publication Critical patent/CA3079477A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3079477A 2017-10-27 2018-10-26 Amplicon region as epigenetic marker for the identification of non-classical monocytes Pending CA3079477A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017125335.1 2017-10-27
DE102017125335.1A DE102017125335B4 (de) 2017-10-27 2017-10-27 Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten
PCT/EP2018/079406 WO2019081707A1 (en) 2017-10-27 2018-10-26 AMPLICON REGION AS AN EPIGENETIC MARKER FOR THE IDENTIFICATION OF NON-CLASSIC MONOCYTES

Publications (1)

Publication Number Publication Date
CA3079477A1 true CA3079477A1 (en) 2019-05-02

Family

ID=64024040

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3079477A Pending CA3079477A1 (en) 2017-10-27 2018-10-26 Amplicon region as epigenetic marker for the identification of non-classical monocytes

Country Status (8)

Country Link
US (1) US11680294B2 (https=)
EP (1) EP3669001B1 (https=)
JP (1) JP2021502806A (https=)
CN (1) CN111247253A (https=)
AU (1) AU2018356572A1 (https=)
CA (1) CA3079477A1 (https=)
DE (1) DE102017125335B4 (https=)
WO (1) WO2019081707A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022191293A1 (https=) * 2021-03-12 2022-09-15

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2869295A1 (en) 2011-05-25 2012-11-29 Brown University Methods using dna methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies
JP6590790B2 (ja) * 2013-04-19 2019-10-16 エピオンティス ゲーエムベーハー 生体サンプルにおける定量的細胞組成を特定する方法
CN105377273A (zh) * 2013-05-22 2016-03-02 耶达研究与发展公司 用于治疗眼睛疾病或病症的人类单核细胞亚群
GB201516975D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes

Also Published As

Publication number Publication date
DE102017125335B4 (de) 2019-10-17
US11680294B2 (en) 2023-06-20
CN111247253A (zh) 2020-06-05
AU2018356572A1 (en) 2020-04-23
WO2019081707A1 (en) 2019-05-02
EP3669001B1 (en) 2024-07-17
EP3669001A1 (en) 2020-06-24
JP2021502806A (ja) 2021-02-04
US20200340053A1 (en) 2020-10-29
DE102017125335A1 (de) 2019-05-02

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