CA3067021A1 - Swallowable capsule, system and method for measuring gastric emptying parameters - Google Patents

Swallowable capsule, system and method for measuring gastric emptying parameters Download PDF

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Publication number
CA3067021A1
CA3067021A1 CA3067021A CA3067021A CA3067021A1 CA 3067021 A1 CA3067021 A1 CA 3067021A1 CA 3067021 A CA3067021 A CA 3067021A CA 3067021 A CA3067021 A CA 3067021A CA 3067021 A1 CA3067021 A1 CA 3067021A1
Authority
CA
Canada
Prior art keywords
capsule
gastric emptying
patient
electrodes
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3067021A
Other languages
English (en)
French (fr)
Inventor
Mir Imran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rani Therapeutics LLC
Original Assignee
Incube Laboratories LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incube Laboratories LLC filed Critical Incube Laboratories LLC
Publication of CA3067021A1 publication Critical patent/CA3067021A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6861—Capsules, e.g. for swallowing or implanting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
    • A61B5/036—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs by means introduced into body tracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/073—Intestinal transmitters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4238—Evaluating particular parts, e.g. particular organs stomach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222—Evaluating particular parts, e.g. particular organs
    • A61B5/4255—Intestines, colon or appendix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0026—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the transmission medium
    • A61B5/0028—Body tissue as transmission medium, i.e. transmission systems where the medium is the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
CA3067021A 2017-06-12 2018-06-12 Swallowable capsule, system and method for measuring gastric emptying parameters Pending CA3067021A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762518246P 2017-06-12 2017-06-12
US62/518,246 2017-06-12
PCT/US2018/037153 WO2018231865A2 (en) 2017-06-12 2018-06-12 Swallowable capsule, system and method for measuring gastric emptying parameters

Publications (1)

Publication Number Publication Date
CA3067021A1 true CA3067021A1 (en) 2018-12-20

Family

ID=64562740

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3067021A Pending CA3067021A1 (en) 2017-06-12 2018-06-12 Swallowable capsule, system and method for measuring gastric emptying parameters

Country Status (7)

Country Link
US (2) US11103187B2 (https=)
EP (1) EP3638111A4 (https=)
JP (3) JP7183194B2 (https=)
CN (2) CN110996754B (https=)
AU (1) AU2018282907B2 (https=)
CA (1) CA3067021A1 (https=)
WO (1) WO2018231865A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US8759284B2 (en) 2009-12-24 2014-06-24 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10689460B2 (en) 2014-05-15 2020-06-23 Incube Labs, Llc PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
CN109464742B (zh) * 2018-12-29 2024-08-09 上海安翰医疗技术有限公司 胃肠道定位开关及其制作方法及消化道定点药物释放胶囊
CN119719690B (zh) * 2025-02-27 2025-06-20 北京亿家老小科技有限公司 一种多维度监控的饱腹感与占胃胶囊效果评估优化方法

Family Cites Families (30)

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US3739279A (en) 1971-06-30 1973-06-12 Corning Glass Works Radio capsule oscillator circuit
US5187154A (en) * 1990-12-13 1993-02-16 Board Of Regents, The University Of Texas System Diagnosis and treatment of humans with diabetes or at risk to develop diabetes
US7160258B2 (en) 2001-06-26 2007-01-09 Entrack, Inc. Capsule and method for treating or diagnosing the intestinal tract
US20060155174A1 (en) * 2002-12-16 2006-07-13 Arkady Glukhovsky Device, system and method for selective activation of in vivo sensors
KR100873683B1 (ko) * 2003-01-25 2008-12-12 한국과학기술연구원 인체통신방법, 인체통신시스템 및 이에 사용되는 캡슐형 내시경
CN1774239A (zh) * 2003-01-29 2006-05-17 埃-皮尔制药公司 用于胃肠道的有效药物递送
EP1690490B1 (en) * 2003-11-11 2012-04-18 Olympus Corporation Capsule type medical device system
JP2005143560A (ja) * 2003-11-11 2005-06-09 Olympus Corp カプセル型医療装置
EP1750755A1 (en) * 2004-06-02 2007-02-14 Technion Research And Development Foundation, Ltd. Methods and formulations for increasing intestinal function
EP1861007A2 (en) * 2005-01-18 2007-12-05 Koninklijke Philips Electronics N.V. Electronically controlled ingestible capsule for sampling fluids in alimentary tract
US8295932B2 (en) * 2005-12-05 2012-10-23 Metacure Limited Ingestible capsule for appetite regulation
WO2008030482A2 (en) * 2006-09-06 2008-03-13 Innurvation Inc System and method for acoustic information exchange involving an ingestible low power capsule
JP5074006B2 (ja) * 2006-11-01 2012-11-14 オリンパス株式会社 カプセル型医療装置
EP3785599B1 (en) * 2007-02-01 2022-08-03 Otsuka Pharmaceutical Co., Ltd. Ingestible event marker systems
CA2724890A1 (en) * 2008-06-18 2009-12-23 The Smartpill Corporation System and method of evaluating a subject with an ingestible capsule
US8235888B2 (en) * 2008-07-08 2012-08-07 Olympus Medical Systems Corp. System for guiding capsule medical device
CN102176862B (zh) * 2008-08-13 2014-10-22 普罗透斯数字保健公司 可摄入电路
CA2746650A1 (en) * 2008-12-11 2010-06-17 Proteus Biomedical, Inc. Evaluation of gastrointestinal function using portable electroviscerography systems and methods of using the same
DE102009007513B4 (de) * 2009-02-05 2011-02-10 Siemens Aktiengesellschaft Ablösen einer Endoskopiekapsel von einer Oberfläche einer Flüssigkeit
KR101432354B1 (ko) * 2009-02-06 2014-08-20 더 프록터 앤드 갬블 캄파니 붕괴성 수분-함유 캡슐
CN102088281B (zh) * 2009-12-04 2013-05-29 北京华清益康科技有限责任公司 一种基于消化道内体液酸碱度的电开关装置
EP2515759A4 (en) 2009-12-23 2015-01-21 Given Imaging Inc METHOD OF ASSESSING CONSTIPATION USING INGREDIENT CAPSULE
CN102905753B (zh) * 2009-12-24 2016-06-29 因卡伯实验室有限责任公司 可吞咽式药剂递送装置和药剂递送方法
EP3603624A1 (en) * 2009-12-24 2020-02-05 Rani Therapeutics, LLC Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
JP5276184B2 (ja) * 2010-01-27 2013-08-28 オリンパス株式会社 電源システム及び、その電源システムを搭載する医療用カプセル装置
WO2011092995A1 (ja) * 2010-01-29 2011-08-04 オリンパスメディカルシステムズ株式会社 カプセル型医療装置およびカプセル型医療装置の製造方法
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Also Published As

Publication number Publication date
CN115844361A (zh) 2023-03-28
US20180353133A1 (en) 2018-12-13
WO2018231865A2 (en) 2018-12-20
US20220008013A1 (en) 2022-01-13
CN110996754A (zh) 2020-04-10
CN110996754B (zh) 2023-01-31
WO2018231865A3 (en) 2020-02-06
AU2018282907A1 (en) 2020-01-30
JP2024116415A (ja) 2024-08-27
JP2020523123A (ja) 2020-08-06
JP2023010877A (ja) 2023-01-20
US11103187B2 (en) 2021-08-31
AU2018282907B2 (en) 2023-12-07
EP3638111A2 (en) 2020-04-22
EP3638111A4 (en) 2021-04-07
JP7183194B2 (ja) 2022-12-05

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