CA3059366C - Anticorps anti-cd137 et procedes d'utilisation correspondants - Google Patents

Anticorps anti-cd137 et procedes d'utilisation correspondants

Info

Publication number
CA3059366C
CA3059366C CA3059366A CA3059366A CA3059366C CA 3059366 C CA3059366 C CA 3059366C CA 3059366 A CA3059366 A CA 3059366A CA 3059366 A CA3059366 A CA 3059366A CA 3059366 C CA3059366 C CA 3059366C
Authority
CA
Canada
Prior art keywords
antibody
amino acid
seq
acid sequence
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3059366A
Other languages
English (en)
Other versions
CA3059366A1 (fr
Inventor
Yanping Xiao
Nicholas Stuart Wilson
Benjamin Maxime Morin
Mark Arthur Findeis
Cornelia Anne Mundt
Marc van Dijk
Dhan Sidhartha Chand
David Adam Savitsky
Dennis John Underwood
Olga Ignatovich
Original Assignee
Agenus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agenus Inc filed Critical Agenus Inc
Priority claimed from PCT/US2018/027310 external-priority patent/WO2018191502A2/fr
Publication of CA3059366A1 publication Critical patent/CA3059366A1/fr
Application granted granted Critical
Publication of CA3059366C publication Critical patent/CA3059366C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente invention concerne des anticorps qui se lient de manière spécifique à CD137 (par exemple, CD137 humain) et améliorent la fonction CD137. L'invention concerne également des compositions pharmaceutiques qui comprennent ces anticorps, des acides nucléiques codant pour ces derniers, des vecteurs d'expression et des cellules hôtes permettant de fabriquer lesdits anticorps, ainsi que des méthodes de traitement d'un sujet à l'aide des anticorps de l'invention.
CA3059366A 2017-04-13 2018-04-12 Anticorps anti-cd137 et procedes d'utilisation correspondants Active CA3059366C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762485365P 2017-04-13 2017-04-13
US62/485,365 2017-04-13
PCT/US2018/027310 WO2018191502A2 (fr) 2017-04-13 2018-04-12 Anticorps anti-cd137 et procédés d'utilisation correspondants

Publications (2)

Publication Number Publication Date
CA3059366A1 CA3059366A1 (fr) 2018-10-18
CA3059366C true CA3059366C (fr) 2026-05-05

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