CA3053853C - Amides de dimethyl amino azetidine et amides heterocycliques a 5 a 7 chainons en tant qu`inhibiteurs de jak - Google Patents

Amides de dimethyl amino azetidine et amides heterocycliques a 5 a 7 chainons en tant qu`inhibiteurs de jak Download PDF

Info

Publication number
CA3053853C
CA3053853C CA3053853A CA3053853A CA3053853C CA 3053853 C CA3053853 C CA 3053853C CA 3053853 A CA3053853 A CA 3053853A CA 3053853 A CA3053853 A CA 3053853A CA 3053853 C CA3053853 C CA 3053853C
Authority
CA
Canada
Prior art keywords
compound
acceptable salt
lung
transplant rejection
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3053853A
Other languages
English (en)
Other versions
CA3053853A1 (fr
Inventor
Daniel D. Long
Cameron Smith
Corbin Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theravance Biopharma R&D IP LLC
Original Assignee
Theravance Biopharma R&D IP LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Biopharma R&D IP LLC filed Critical Theravance Biopharma R&D IP LLC
Publication of CA3053853A1 publication Critical patent/CA3053853A1/fr
Application granted granted Critical
Publication of CA3053853C publication Critical patent/CA3053853C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Il est décrit des composés de formule (I) [voir la formule I] et des composés de formule (IB) [voir la formule IB] dans laquelle les variables sont définies dans la description, ou un sel pharmaceutiquement acceptable de ceux-ci, qui sont utiles en tant qu'inhibiteurs de Janus kinase. Il est également décrit des compositions pharmaceutiques comprenant de tels composés et des procédés d'utilisation de tels composés pour traiter des maladies respiratoires.
CA3053853A 2018-09-04 2019-09-03 Amides de dimethyl amino azetidine et amides heterocycliques a 5 a 7 chainons en tant qu`inhibiteurs de jak Active CA3053853C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862726562P 2018-09-04 2018-09-04
US201862726583P 2018-09-04 2018-09-04
US62/726,562 2018-09-04
US62/726,583 2018-09-04

Publications (2)

Publication Number Publication Date
CA3053853A1 CA3053853A1 (fr) 2020-03-04
CA3053853C true CA3053853C (fr) 2023-10-10

Family

ID=69718592

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3053853A Active CA3053853C (fr) 2018-09-04 2019-09-03 Amides de dimethyl amino azetidine et amides heterocycliques a 5 a 7 chainons en tant qu`inhibiteurs de jak

Country Status (1)

Country Link
CA (1) CA3053853C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113318097A (zh) * 2021-04-29 2021-08-31 珠海瑞思普利医药科技有限公司 一种抗特发性肺纤维化的粉雾剂及制备方法

Also Published As

Publication number Publication date
CA3053853A1 (fr) 2020-03-04

Similar Documents

Publication Publication Date Title
US11878977B2 (en) JAK inhibitors containing a 4-membered heterocyclic amide
US11634419B2 (en) Dimethyl amino azetidine amides as JAK inhibitors
US11713315B2 (en) 5 to 7 membered heterocyclic amides as JAK inhibitors
US11702415B2 (en) Crystalline hydrate of a JAK inhibitor compound
CA3053853C (fr) Amides de dimethyl amino azetidine et amides heterocycliques a 5 a 7 chainons en tant qu`inhibiteurs de jak

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121

EEER Examination request

Effective date: 20210121