CA3048247A1 - Procedes, appareils et systemes permettant d'analyser des souches de micro-organismes dans des communautes heterogenes complexes, de determiner leurs interactions et relations fon ctionnelles, et gestion de diagnostics et d'etats biologiques basee sur ceux-ci - Google Patents

Procedes, appareils et systemes permettant d'analyser des souches de micro-organismes dans des communautes heterogenes complexes, de determiner leurs interactions et relations fon ctionnelles, et gestion de diagnostics et d'etats biologiques basee sur ceux-ci Download PDF

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Publication number
CA3048247A1
CA3048247A1 CA3048247A CA3048247A CA3048247A1 CA 3048247 A1 CA3048247 A1 CA 3048247A1 CA 3048247 A CA3048247 A CA 3048247A CA 3048247 A CA3048247 A CA 3048247A CA 3048247 A1 CA3048247 A1 CA 3048247A1
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Canada
Prior art keywords
sample
microorganism
unique
strains
state
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Abandoned
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CA3048247A
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English (en)
Inventor
Mallory EMBREE
Cameron Joseph MARTINO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Native Microbials Inc
Original Assignee
Ascus Biosciences Inc
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Publication date
Application filed by Ascus Biosciences Inc filed Critical Ascus Biosciences Inc
Publication of CA3048247A1 publication Critical patent/CA3048247A1/fr
Abandoned legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/06—Quantitative determination
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20—Probabilistic models
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B10/00—ICT specially adapted for evolutionary bioinformatics, e.g. phylogenetic tree construction or analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/20—Sequence assembly
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne des procédés, des appareils et des systèmes permettant d'analyser des souches de micro-organismes dans des communautés hétérogènes complexes, de déterminer leurs interactions et relations fonctionnelles, et la gestion de diagnostics et d'états biologiques basée sur ceux-ci. L'invention concerne également des méthodes de diagnostic, d'analyse et de traitement d'états et d'aberrations/déviations d'états, y compris des traitements, tels que des modificateurs bioréactifs, tels que des modificateurs bioréactifs comprenant des ensembles microbiens synthétiques.
CA3048247A 2016-12-28 2017-12-28 Procedes, appareils et systemes permettant d'analyser des souches de micro-organismes dans des communautes heterogenes complexes, de determiner leurs interactions et relations fon ctionnelles, et gestion de diagnostics et d'etats biologiques basee sur ceux-ci Abandoned CA3048247A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662439804P 2016-12-28 2016-12-28
US62/439,804 2016-12-28
US201762560174P 2017-09-18 2017-09-18
US62/560,174 2017-09-18
PCT/US2017/068753 WO2018126033A1 (fr) 2016-12-28 2017-12-28 Procédés, appareils et systèmes permettant d'analyser des souches de micro-organismes dans des communautés hétérogènes complexes, de déterminer leurs interactions et relations fonctionnelles, et gestion de diagnostics et d'états biologiques basée sur ceux-ci

Publications (1)

Publication Number Publication Date
CA3048247A1 true CA3048247A1 (fr) 2018-07-05

Family

ID=62710026

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3048247A Abandoned CA3048247A1 (fr) 2016-12-28 2017-12-28 Procedes, appareils et systemes permettant d'analyser des souches de micro-organismes dans des communautes heterogenes complexes, de determiner leurs interactions et relations fon ctionnelles, et gestion de diagnostics et d'etats biologiques basee sur ceux-ci

Country Status (8)

Country Link
EP (1) EP3562956A4 (fr)
JP (1) JP2020507308A (fr)
CN (1) CN110392738A (fr)
AU (1) AU2017388532A1 (fr)
CA (1) CA3048247A1 (fr)
IL (1) IL267646A (fr)
MX (1) MX2019007764A (fr)
WO (1) WO2018126033A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017016924A (es) 2015-06-25 2018-08-15 Ascus Biosciences Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
CA3010505A1 (fr) 2016-01-07 2017-07-13 Ascus Biosciences, Inc. Procedes pour ameliorer la production de lait par administration de consortiums microbiens
AU2017386658A1 (en) 2016-12-28 2019-07-25 Native Microbials, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
CA3057692A1 (fr) 2017-04-28 2018-11-01 Ascus Biosciences, Inc. Procedes favorisant des regimes riches en energie et/ou en cereales au moyen d'un bio-ensemble synthetique de microbes
IL264581A (en) * 2019-01-31 2020-08-31 Segal Eran Predicting blood metabolites
EP4172851A1 (fr) * 2020-06-24 2023-05-03 Université de Lausanne Moyens et procédés de classification de microbes
KR102241357B1 (ko) * 2020-10-20 2021-04-16 주식회사 에이치이엠 머신러닝 모델을 이용하여 대장용종을 진단하는 방법 및 장치
CN112662795B (zh) * 2021-01-26 2023-12-15 苏州系统医学研究所 用于感染性病原体检测的阳性对照品及其制备方法与应用
CN112951333A (zh) * 2021-01-27 2021-06-11 天津大学 以f2噬菌体为模式病毒预测冠状病毒消抗模型评价方法
CN113096737B (zh) * 2021-03-26 2023-10-31 北京源生康泰基因科技有限公司 一种用于对病原体类型进行自动分析的方法及系统
KR102304402B1 (ko) * 2021-03-26 2021-09-24 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 비만 여부를 판별하는 방법 및 진단 장치
KR102304399B1 (ko) * 2021-03-26 2021-09-24 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 고혈당을 판별하는 방법 및 진단 장치
KR20220158950A (ko) * 2021-05-25 2022-12-02 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 소화기 장애 유무를 판별하는 방법 및 진단 장치
KR20220158948A (ko) * 2021-05-25 2022-12-02 주식회사 에이치이엠파마 머신러닝 모델을 이용하여 복부팽만 유무를 판별하는 방법 및 진단 장치

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010065625A1 (fr) * 2008-12-02 2010-06-10 Danisco A/S Souches et procédés pour améliorer la santé et/ou les performances de ruminants
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
CN104171413B (zh) * 2014-08-01 2016-04-13 农业部沼气科学研究所 一种含厌氧菌K.paraultunense KD-1发酵液和羽毛粉的肉型家禽饲料
CN104814278A (zh) * 2015-04-15 2015-08-05 江苏师范大学 一种提高奶牛产奶量的微生态制剂
MX2017016924A (es) * 2015-06-25 2018-08-15 Ascus Biosciences Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.

Also Published As

Publication number Publication date
JP2020507308A (ja) 2020-03-12
MX2019007764A (es) 2019-10-15
EP3562956A4 (fr) 2020-10-14
WO2018126033A1 (fr) 2018-07-05
IL267646A (en) 2019-08-29
EP3562956A1 (fr) 2019-11-06
CN110392738A (zh) 2019-10-29
AU2017388532A1 (en) 2019-07-25

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