CA3045244C - (aza)indole, benzothiophene et benzofuran-3-sulfonamides - Google Patents

(aza)indole, benzothiophene et benzofuran-3-sulfonamides

Info

Publication number
CA3045244C
CA3045244C CA3045244A CA3045244A CA3045244C CA 3045244 C CA3045244 C CA 3045244C CA 3045244 A CA3045244 A CA 3045244A CA 3045244 A CA3045244 A CA 3045244A CA 3045244 C CA3045244 C CA 3045244C
Authority
CA
Canada
Prior art keywords
fluoro
unsubstituted
sulfonamide
indole
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3045244A
Other languages
English (en)
Other versions
CA3045244A1 (fr
Inventor
Christa E. MUELLER
Cecile Pegurier
Michael Louis Robert Deligny
Ali El-Tayeb
Joerg HOCKEMEYER
Marie LEDECQ
Joel Mercier
Laurent Provins
Nader M. BOSHTA
Sanjay BHATTARAI
Vigneshwaran NAMASIVAYAM
Mario Funke
Lukas SCHWACH
Sabrina GOLLOS
Daniel VON LAUFENBERG
Anais Barre
Original Assignee
UCB Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Pharma GmbH filed Critical UCB Pharma GmbH
Priority claimed from PCT/EP2017/084602 external-priority patent/WO2018122232A1/fr
Publication of CA3045244A1 publication Critical patent/CA3045244A1/fr
Application granted granted Critical
Publication of CA3045244C publication Critical patent/CA3045244C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

Il est décrit des composés de la formule I-2, (voir formule I-2) et des sels, des solvates et des isotopes connexes acceptables sur le plan pharmaceutique ayant des propriétés de modulation GPR17 utiles pour le traitement ou la prévention d'une vaste gamme de maladies liées au système nerveux central (SNC) et d'autres maladies, particulièrement la prévention et le traitement de maladies ou de troubles myélinisants.
CA3045244A 2016-12-28 2017-12-27 (aza)indole, benzothiophene et benzofuran-3-sulfonamides Active CA3045244C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16207137.7 2016-12-28
EP16207137 2016-12-28
PCT/EP2017/084602 WO2018122232A1 (fr) 2016-12-28 2017-12-27 (aza)indole, benzothiophène et benzofuran-3-sulfonamides

Publications (2)

Publication Number Publication Date
CA3045244A1 CA3045244A1 (fr) 2018-07-05
CA3045244C true CA3045244C (fr) 2026-04-07

Family

ID=

Similar Documents

Publication Publication Date Title
AU2022235580B2 (en) (AZA)indole-, benzothiophene-, and benzofuran-3-sulfonamides
JP7026194B2 (ja) アザベンズイミダゾール及びａｍａｐ受容体調節因子としてのその使用
AU2019289788B2 (en) Pyridinyl and pyrazinyl-(aza)indolsulfonamides
CN105814054B (zh) 作为tnf活性调节剂的稠合咪唑和吡唑衍生物
TW201004940A (en) Heteroaryl compounds and uses thereof
WO2017040963A1 (fr) Inhibiteurs de hdac8 bicyclique [6,6] fusionnée
WO2017184658A1 (fr) Inhibiteurs de nav1.7 à base d'acyl-sulfonamide
CA3045244C (fr) (aza)indole, benzothiophene et benzofuran-3-sulfonamides
EA039985B1 (ru) (аза)индол-, бензотиофен- и бензофуран-3-сульфонамиды
CN119613397A (zh) N杂芳并环-3-磺酰胺类化合物及其用于制备gpr17受体抑制剂中的用途
BR112019012550B1 (pt) Compostos (aza)indol-, benzotiofeno- e benzofuran-3- sulfonamidas, uso de tais compostos e composição farmacêutica compreendendo tais compostos