CA3035109C - Microscope a balayage utilisant un filtre de balayage en mosaique - Google Patents
Microscope a balayage utilisant un filtre de balayage en mosaique Download PDFInfo
- Publication number
- CA3035109C CA3035109C CA3035109A CA3035109A CA3035109C CA 3035109 C CA3035109 C CA 3035109C CA 3035109 A CA3035109 A CA 3035109A CA 3035109 A CA3035109 A CA 3035109A CA 3035109 C CA3035109 C CA 3035109C
- Authority
- CA
- Canada
- Prior art keywords
- detector array
- filters
- specimen
- array
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000003595 spectral effect Effects 0.000 claims abstract description 53
- 238000003384 imaging method Methods 0.000 claims description 61
- 238000000701 chemical imaging Methods 0.000 claims description 45
- 230000033001 locomotion Effects 0.000 claims description 44
- 238000005286 illumination Methods 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 31
- 230000003287 optical effect Effects 0.000 claims description 22
- 239000003086 colorant Substances 0.000 claims description 18
- 230000005540 biological transmission Effects 0.000 claims description 13
- 230000003213 activating effect Effects 0.000 claims description 2
- 238000003491 array Methods 0.000 abstract description 12
- 238000001228 spectrum Methods 0.000 description 14
- 238000010586 diagram Methods 0.000 description 12
- 230000005284 excitation Effects 0.000 description 9
- 238000000799 fluorescence microscopy Methods 0.000 description 9
- 238000013480 data collection Methods 0.000 description 7
- 238000013461 design Methods 0.000 description 7
- 238000012935 Averaging Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 6
- 238000006073 displacement reaction Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000005424 photoluminescence Methods 0.000 description 3
- 238000002073 fluorescence micrograph Methods 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000004065 semiconductor Substances 0.000 description 2
- 241000252506 Characiformes Species 0.000 description 1
- 238000000018 DNA microarray Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000000295 emission spectrum Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000002493 microarray Methods 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 238000003498 protein array Methods 0.000 description 1
- 239000002096 quantum dot Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Classifications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
- G02B21/365—Control or image processing arrangements for digital or video microscopes
- G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0052—Optical details of the image generation
- G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B5/00—Optical elements other than lenses
- G02B5/20—Filters
- G02B5/201—Filters in the form of arrays
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/10—Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from different wavelengths
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/56—Cameras or camera modules comprising electronic image sensors; Control thereof provided with illuminating means
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/60—Control of cameras or camera modules
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
- H04N23/80—Camera processing pipelines; Components thereof
- H04N23/84—Camera processing pipelines; Components thereof for processing colour signals
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
- H04N25/10—Circuitry of solid-state image sensors [SSIS]; Control thereof for transforming different wavelengths into image signals
- H04N25/11—Arrangement of colour filter arrays [CFA]; Filter mosaics
- H04N25/13—Arrangement of colour filter arrays [CFA]; Filter mosaics characterised by the spectral characteristics of the filter elements
Abstract
L'invention concerne un réseau de filtres de balayage en mosaïque comprenant une pluralité de tuiles identiques, chaque tuile ayant n rangées et m colonnes, n étant égal ou supérieur à 1 et m étant égal ou supérieur à 2. Une rangée de tuiles s'étend sur une largeur d'un réseau de détecteurs et constitue un motif de base. Le motif de base est répété M fois et chaque répétition est latéralement décalée, dans une direction, d'une largeur de pixel. Le motif de base et les répétitions décalées latéralement constituent un motif de répétition. Il existe MxN filtres sélectionnés dans le groupe comprenant un ou plusieurs des éléments suivants : des filtres RGBW, des filtres d'émission de fluorescence et une série de filtres à bande spectrale étroite couvrant une plage spectrale continue. Les réseaux de filtres de balayage en mosaïque peuvent être utilisés avec un microscope à balayage ou une caméra à balayage.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662380224P | 2016-08-26 | 2016-08-26 | |
| US62/380,224 | 2016-08-26 | ||
| US201762550278P | 2017-08-25 | 2017-08-25 | |
| US62/550,278 | 2017-08-25 | ||
| PCT/CA2017/000196 WO2018035597A1 (fr) | 2016-08-26 | 2017-08-25 | Microscope à balayage utilisant un filtre de balayage en mosaïque |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3035109A1 CA3035109A1 (fr) | 2018-03-01 |
| CA3035109C true CA3035109C (fr) | 2024-01-02 |
Family
ID=61246031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3035109A Active CA3035109C (fr) | 2016-08-26 | 2017-08-25 | Microscope a balayage utilisant un filtre de balayage en mosaique |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20210278648A1 (fr) |
| CA (1) | CA3035109C (fr) |
| WO (1) | WO2018035597A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3413557B1 (fr) * | 2017-06-08 | 2021-03-03 | IMEC vzw | Procédé, capteur d'image et dispositif pour d'acquisition d'une image d'un objet |
| EP3817375A4 (fr) * | 2019-09-09 | 2021-08-11 | Guangdong Oppo Mobile Telecommunications Corp., Ltd. | Capteur d'images, module de caméra, terminal mobile et procédé de capture d'images |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7692610B2 (en) * | 2005-11-30 | 2010-04-06 | Semiconductor Energy Laboratory Co., Ltd. | Display device |
| US9575304B2 (en) * | 2012-06-25 | 2017-02-21 | Huron Technologies International Inc. | Pathology slide scanners for fluorescence and brightfield imaging and method of operation |
| CN106999021B (zh) * | 2014-06-05 | 2021-06-04 | 海德堡大学 | 用于多光谱成像的方法和部件 |
| DE102015011441A1 (de) * | 2015-09-01 | 2017-03-02 | Carl Zeiss Meditec Ag | Fluoreszenzlichtdetektionssystem und Mikroskopiesystem |
-
2017
- 2017-08-25 CA CA3035109A patent/CA3035109C/fr active Active
- 2017-08-25 US US16/328,644 patent/US20210278648A1/en active Pending
- 2017-08-25 WO PCT/CA2017/000196 patent/WO2018035597A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018035597A1 (fr) | 2018-03-01 |
| CA3035109A1 (fr) | 2018-03-01 |
| US20210278648A1 (en) | 2021-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |
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| EEER | Examination request |
Effective date: 20201216 |