CA3027028A1 - Compositions et procedes de detection d'une predisposition a une maladie cardiovasculaire - Google Patents

Compositions et procedes de detection d'une predisposition a une maladie cardiovasculaire Download PDF

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Publication number
CA3027028A1
CA3027028A1 CA3027028A CA3027028A CA3027028A1 CA 3027028 A1 CA3027028 A1 CA 3027028A1 CA 3027028 A CA3027028 A CA 3027028A CA 3027028 A CA3027028 A CA 3027028A CA 3027028 A1 CA3027028 A1 CA 3027028A1
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CA
Canada
Prior art keywords
nucleic acid
kit
cpg dinucleotide
acid primer
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3027028A
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English (en)
Inventor
Robert Philibert
Meeshanthini DOGAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Iowa Research Foundation UIRF
Original Assignee
University of Iowa Research Foundation UIRF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Iowa Research Foundation UIRF filed Critical University of Iowa Research Foundation UIRF
Publication of CA3027028A1 publication Critical patent/CA3027028A1/fr
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

L'invention concerne des procédés et des compositions permettant de détecter une prédisposition à une maladie cardiovasculaire chez un individu.
CA3027028A 2016-06-08 2017-06-08 Compositions et procedes de detection d'une predisposition a une maladie cardiovasculaire Pending CA3027028A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662347479P 2016-06-08 2016-06-08
US62/347,479 2016-06-08
US201762455468P 2017-02-06 2017-02-06
US62/455,468 2017-02-06
PCT/US2017/036555 WO2017214397A1 (fr) 2016-06-08 2017-06-08 Compositions et procédés de détection d'une prédisposition à une maladie cardiovasculaire

Publications (1)

Publication Number Publication Date
CA3027028A1 true CA3027028A1 (fr) 2017-12-14

Family

ID=59078226

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3027028A Pending CA3027028A1 (fr) 2016-06-08 2017-06-08 Compositions et procedes de detection d'une predisposition a une maladie cardiovasculaire

Country Status (7)

Country Link
US (2) US11414704B2 (fr)
EP (2) EP3472344B1 (fr)
JP (2) JP2019520066A (fr)
CN (2) CN109906275B (fr)
AU (2) AU2017277666B2 (fr)
CA (1) CA3027028A1 (fr)
WO (1) WO2017214397A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3472344B1 (fr) 2016-06-08 2021-03-31 University of Iowa Research Foundation Compositions de détection d'une prédisposition à une maladie cardiovasculaire
GB201804262D0 (en) * 2018-03-16 2018-05-02 Samsung Electronics Co Ltd Determining a cause of a trend in vital sign data of a subject
GB201810897D0 (en) * 2018-07-03 2018-08-15 Chronomics Ltd Phenotype prediction
US11017268B2 (en) * 2019-06-21 2021-05-25 Dell Products L.P. Machine learning system for identifying potential escalation of customer service requests
CN110610487A (zh) * 2019-08-29 2019-12-24 上海杏脉信息科技有限公司 一种测量心影增大的方法与装置
US11817214B1 (en) 2019-09-23 2023-11-14 FOXO Labs Inc. Machine learning model trained to determine a biochemical state and/or medical condition using DNA epigenetic data
US11795495B1 (en) * 2019-10-02 2023-10-24 FOXO Labs Inc. Machine learned epigenetic status estimator
US20230313302A1 (en) * 2020-09-04 2023-10-05 University Of Iowa Research Foundation Methods and compositions for predicting and/or monitoring diabetes and treatments therefor
EP4208570A1 (fr) * 2020-09-04 2023-07-12 Cardio Diagnostics, Inc. Méthodes et compositions visant à prédire et/ou à surveiller une maladie cardiovasculaire et traitements associés
US11227690B1 (en) * 2020-09-14 2022-01-18 Opendna Ltd. Machine learning prediction of therapy response
CN113355420B (zh) * 2021-06-30 2022-11-11 湖南灵康医疗科技有限公司 一种jak3启动子甲基化的检测引物组合物、应用及检测方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
WO2001077384A2 (fr) 2000-04-07 2001-10-18 Epigenomics Ag Detection de polymorphismes du nucleotide simple et de methylation de cytosine
DE10061338A1 (de) * 2000-12-06 2002-06-20 Epigenomics Ag Diagnose von mit Angiogenese assoziierten Krankheiten
EP1644537A2 (fr) 2003-07-11 2006-04-12 Wisconsin Alumni Research Foundation Methode d'evaluation d'une predisposition comportementale
WO2005087953A2 (fr) * 2004-03-05 2005-09-22 Applera Corporation Polymorphismes genetiques associes a des maladies coronariennes, procedes de detection et utilisations
FI20041340A0 (fi) * 2004-10-15 2004-10-15 Jurilab Ltd Oy Menetelmä ja testipakkaus äkillisen sydäninfarktin riskin havaitsemiseksi
JP5590697B2 (ja) * 2005-03-11 2014-09-17 セレラ コーポレーション 冠動脈心疾患に関連する遺伝的多型、その検出方法および使用
US7851154B2 (en) * 2005-07-22 2010-12-14 Simon Daniel Spivack GC tag-modified bisulfite genomic DNA sequencing for continuous methylation spectra
US20100234242A1 (en) * 2007-01-23 2010-09-16 Arturas Petronis DNA Methylation Changes Associated with Major Psychosis
AP2011005546A0 (en) 2008-06-25 2011-02-28 Baylor Res Intitute Blood transcriptional signature of mycobacterium tuberculosis infection.
WO2010129354A2 (fr) * 2009-04-28 2010-11-11 University Of Iowa Research Foundation Compositions et procédés de détection d'une prédisposition à un trouble d'utilisation de substance
CA2806301A1 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methodes de detection de maladies ou de pathologies cardiovasculaires
WO2013001504A1 (fr) * 2011-06-30 2013-01-03 Centre Hospitalier Universitaire Vaudois (C.H.U.V.) Polymorphismes associés à une absence de réponse à un traitement de l'hépatite c ou à une prédisposition à une clairance non spontanée de l'hépatite c
ES2650387T3 (es) 2012-03-14 2018-01-18 Ruprecht-Karls-Universität Heidelberg Firmas epigenéticas como marcador de cardiomiopatías e insuficiencias miocárdicas
WO2016057485A1 (fr) * 2014-10-06 2016-04-14 The Johns Hopkins University Biomarqueur spécifique de la méthylation d'adn et du génotype pour prédiction d'un état de stress post-traumatique
US9984201B2 (en) 2015-01-18 2018-05-29 Youhealth Biotech, Limited Method and system for determining cancer status
EP3472344B1 (fr) 2016-06-08 2021-03-31 University of Iowa Research Foundation Compositions de détection d'une prédisposition à une maladie cardiovasculaire

Also Published As

Publication number Publication date
WO2017214397A1 (fr) 2017-12-14
EP3472344B1 (fr) 2021-03-31
CN116904572A (zh) 2023-10-20
JP2019520066A (ja) 2019-07-18
US20230008544A1 (en) 2023-01-12
EP3907300A1 (fr) 2021-11-10
EP3472344A1 (fr) 2019-04-24
US11414704B2 (en) 2022-08-16
AU2023254965A1 (en) 2023-11-16
AU2017277666A1 (en) 2019-01-03
US20190264286A1 (en) 2019-08-29
AU2017277666B2 (en) 2023-07-27
CN109906275B (zh) 2023-05-12
CN109906275A (zh) 2019-06-18
JP2022166165A (ja) 2022-11-01

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