CA3024645A1

CA3024645A1 - High cannabinoid concentration cannabis vape oil, method of use and of making same

Info

Publication number: CA3024645A1
Application number: CA3024645A
Authority: CA
Inventors: Shane H. Morris; Patrick Woods; Max Alsayar
Original assignee: Hexo Operations Inc
Current assignee: Hexo Operations Inc
Priority date: 2018-11-19
Filing date: 2018-11-19
Publication date: 2019-01-18

Abstract

The present disclosure relates to cannabis vaping oil for use in a vaping device. The cannabis oil includes a mixture of a cannabinoid source, a solubilizing aiding agent and minimal amount of carrier oil. The cannabinoid source and carrier oil being respective proportions sufficient to obtain high concentration of a cannabinoid.

Description

HIGH CANNABINOID CONCENTRATION CANNABIS VAPE OIL, METHOD OF
USE AND OF MAKING SAME
TECHNICAL FIELD
[01] This application generally relates to the field of cannabis oil for vaping.
BACKGROUND

[02] Conventionally, electronic vaping devices uti1i7e a liquid supply reservoir that contains a liquid material. The liquid material is drawn toward a heater via a wick, where the heater vaporizes the liquid material, and the vaporized liquid is entrained in an air flow that is discharged into a vaper's mouth for consumption and ultimately for a desired physiological effect.

[03] In order for the liquid material to properly operate in the vaping device, the liquid material must have properties, which are suitable for the liquid to vaporize, namely the liquid must have a proper viscosity such that it can be adequately metered to the heating element by the capillary action of the wick. For instance, a liquid that is too viscous will not function well because the wick will have difficulty transferring the liquid to the heating element.

[04] This viscosity requirement for proper operation of the vaping device is an important factor that currently limits the effectiveness of vaping oils in the recreational or medicinal vaping cannabis industry. Indeed, viscosity of the active ingredient (i.e., cannabinoid) source material is typically high due to the inherent physicochemical properties of the source material components, and as such, one must dilute the cannabinoid source material in a proper solvent (e.g., carrier oils, water, etc.), often in large proportions in order to obtain a viscosity which is suitable for proper operation of the vaping device. In other words, cannabis vaping oils are limited in terms of the cannabinoid concentrations they can ultimately contain because of the necessary dilution of the cannabinoid source material.

[05] This deficiency of cannabis vaping oils is not an issue in other forms of cannabis consumption, such as ingestible oils, where viscosity is not a key factor for the cannabis oil formulation. For instance, it is simple for the person consuming the oil orally to adjust the amount of oil ingested according to desired cannabinoid intake. So, if the oil is of relatively low cannabinoid concentration, the person can take a little more to achieve the desired effect, without much inconvenience. Alternatively, the oil can be made more viscous to increase the cannabinoid concentration, which from the perspective of oral ingestion is not a problem.

[06] However, when the cannabis oil is vaporized and inhaled, the user experience is different and the cannabinoid concentration matters to achieve the desired physical effect, which the user typically correlates to a number of puffs. Users generally desire to obtain a quick effect with the minimum number of puffs; hence vaping oil with a high cannabinoid concentration is desired.

[07] Despite the widespread population of vaping, cannabis vaping oils with high concentrations of a cannabinoid for use in a vaping device have remained elusive.
SUMMARY

[08] This Summary is provided to introduce a selection of concepts in a simplified form that are further described below in the Detailed Description. This Summary is not intended to identify key aspects or essential aspects of the claimed subject matter.

[09] As embodied and broadly described herein, the present disclosure relates to a cannabis oil for use in a vaping device configured for feeding the cannabis oil to a vaporization system having a heating element supplied with cannabis oil to vaporize the cannabis oil through a wick system, the cannabis oil comprising at least 300 mg/ml of a cannabinoid.

[10] As embodied and broadly described herein, the present disclosure relates to a cannabis oil for vaping, the cannabis oil comprising a mixture of a cannabinoid source, a solubilizing aiding agent, and carrier oil, and at least 300 ml/ml of a cannabinoid.

[11] As embodied and broadly described herein, the present disclosure relates to a cannabis vaping oil comprising a cannabis concentrate comprising plant waxes, medium chain triglycerides (MCI), and 300 mg/ml of a cannabinoid.

[12] As embodied and broadly described herein, the present disclosure relates to a cartridge component of an electronic vaping device, comprising a liquid reservoir containing the herein described cannabis oil and a vaporization system having a heating element and a wick configured for supplying cannabinoid oil to the heating element such that the cannabinoid oil can be heated at a temperature sufficient in order to be vaporized.

[13] As embodied and broadly described herein, the present disclosure relates to a cannabis concentrate for mixing with a carrier oil to make cannabis oil for use in a vaping device, the cannabis concentrate comprising a plant wax and being free of winterization ethanol.

[14] As embodied and broadly described herein, the present disclosure relates to a process for making a cannabis oil for use in a vaping device, comprising the following steps: extraction of a cannabinoid and waxes from cannabis plant material with carbon dioxide to obtain an extract containing the cannabinoid and waxes, adding carrier oil to the extract containing the cannabinoid and waxes to make the cannabis oil, the carrier oil and extract being present in respective proportions so as to obtain cannabis oil suitable for use in a vaping device and containing 300 mg/ml of the cannabinoid.

[15] As embodied and broadly described herein, the present disclosure relates to a method of manufacturing cannabis vaping oil suitable for use in a vaping device, the vaping device being configured for using a vaping oil having a viscosity at room temperature below a threshold, the method comprising: providing a cannabinoid source having a viscosity at room temperature which is above the threshold; providing a carrier oil having a viscosity below the threshold at room temperature; and diluting the cannabinoid source with the carrier oil in presence of a solubilizing aiding agent to form a mixture, wherein the proportions of cannabinoid source and carrier oil are selected such that the mixture has a viscosity below the threshold and 300 mg/ml of a cannabinoid.

[16] All features of exemplary embodiments which are described in this disclosure and are not mutually exclusive can be combined with one another. Elements of one embodiment can be utilized in the other embodiments without further mention. Other aspects and features of the present invention will become apparent to those ordinarily skilled in the art upon review of the following description of specific embodiments in conjunction with the accompanying Figures.
BRIEF DESCRIPTION OF THE DRAWINGS

[17] A detailed description of specific exemplary embodiments is provided herein below with reference to the accompanying drawings in which:

[18] Fig. IA is a plan view of a cartridge component of an electronic vaping device in accordance with an embodiment of the present disclosure.

[19] Fig. 1B is an isometric view of a battery compartment component of an electronic vaping device in accordance with an embodiment of the present disclosure.

[20] In the drawings, exemplary embodiments are illustrated by way of example. It is to be expressly understood that the description and drawings are only for the purpose of illustrating certain embodiments and are an aid for understanding. They are not intended to be a definition of the limits of the invention.
DETAILED DESCRIPTION

[21] A detailed description of one or more embodiments of the invention is provided below along with accompanying figures that illustrate the principles of the invention. The invention is described in connection with such embodiments, but the invention is not limited to any embodiment. The scope of the invention is limited only by the claims. Numerous specific details are set forth in the following description in order to provide a thorough understanding of the invention. These details are provided for the purpose of non-limiting examples and the invention may be practiced according to the claims without some or all of these specific details. For the purpose of clarity, technical material that is known in the technical fields related to the invention has not been described in detail so that the invention is not unnecessarily obscured.

[22] The present inventors have through extensive R&D work surprisingly and unexpectdly discovered a process for producing a cannabis vaping oil that includes a high concentration of a cannabinoid with minimal amounts of carrier oil, where the vaping oil has a viscosity suitable for use in a vaping device, i.e., for feeding the vaping oil to a heating element through a wick contained in the vaping device.

[23] The process of obtaining the herein described cannabis vaping oil includes diluting a cannabinoid source having a viscosity at room temperature which is above a viscosity threshold suitable for use in the vaping device to the point of obtaining a desired viscosity with minimal amounts of carrier oil, where the carrier oil has a viscosity below the threshold. Generally speaking, several options exist to obtain cannabis vaping oil having the herein described desired high concentration of a cannabinoid with minimal amounts of carrier oil.

[24] In one option, one can dilute the cannabinoid source in carrier oil in presence of a solubilizing aiding agent, where the solubilizing aiding agent is endogenously present in the cannabinoid source. The dilution creates a mixture that has a sufficiently lower viscosity than the cannabinoid source without the carrier oil, but with minimal amounts of the carrier oil so as to obtain the herein described desired high concentration of the cannabinoid. The inventors believe that the solubilizing aiding agent increases the solubility of cannabinoid in the mixture, which works toward the objective of increasing the concentrtion of cannabinoid in the vaping oil.
Furthermore, when the mixture is loaded into a cartridge component of a vaping device with a pipette at room temperature, the mixture flows in and out of the pipette into the cartridge without much difficulty. In other words, the mixture behaves like a liquid at room temperature.

[25] In a second option, one can dilute the cannabis concentrate in carrier oil in presence of a solubilizing aiding agent, where the solubilizing aiding agent is incorporated into the vaping oil.
The dilution also creates a mixture that has a sufficiently lower viscosity than the cannabis concentrate without the carrier oil, and with minimal amounts of the carrier oil so as to obtain the herein described desired high concentration of a cannabinoid. When the mixture is loaded into a cartridge component of a vaping device with a pipette at room temperature, the mixture also flows in and out of the pipette into the cartridge without much difficulty. In other words, the mixture also behaves like a liquid at room temperature.

[26] In a third option, one can implement the first and second options and dilute the cannabis concentrate in carrier oil in presence of more than one solubilizing aiding agent, where at least one solubilizing aiding agent is endogenously present in the cannabinoid source and where at least one solubilizing aiding agent is incorporated into the vaping oil. In this option, the solubilizing aiding agents can be the same or different materials.
Solubilizing aiding agent

[27] In a practical implementation, the solubilizing aiding agent operates to aid in solubilizing the cannabinoid source in the carrier oil. Advantageously, the presence of the solubilizing aiding agent affords one to dilute the high viscosity cannabinoid source with minimal amounts of carrier oil, thus, obtaining a vaping oil with higher cannabinoid concentrations than would be possible without the solubilizing aiding agent.

[28] In one embodiment, the solubilizing aiding agent is a compound which is incorporated into the cannabis vaping oil to assist in solubilizing the cannabinoid in the carrier oil. In this embodiment, the solubilizing aiding agent can be a compound which is of plant origin or which is biosynthesized.

[29] In one embodiment, the solubilizing aiding agent is a compound which is endogenously present in the cannabinoid source, for example in cannabis plant material and which is not significantly depleted when processing the plant material to extract the cannabinoid(s) such that sufficient solubilizing aiding agent remains in the resulting cannabis concentrate to perform its solubilizing aiding function.

[30] The solubilizing aiding agent can be a single material or a blend of different materials.
Optionally, the rate of addition of the additive to the cannabis concentrate can be adjusted according to expected storage or the vaping device's operational parameters.

[31] In one embodiment, the solubilizing aiding agent includes one or more terpene(s), one or more plant wax(es), or any combinations thereof.
Cannabinoid source

[32] In one embodiment, the cannabinoid source includes a semi-synthetic cannabinoid. The manufacture of cannabinoid compounds and their analogs using semi-synthetic means involves contacting an appropriate substrate with one of the cannabinoid synthase enzymes. For instance, tetrahydrocannabinolic acid (THCA) or its analogs can be manufactured semi-synthetically by contacting cannabigerolic acid (CBGA) or an appropriately substituted derivative of CBGA with THC synthase to obtain the corresponding THCA or THCA analog respectively.
Other means for manufacturing semi-synthetically cannabinoids may involve, for example, cell culture of genetically modified cells, which have been modified so as to produce cannabinoids.

[33] In another embodiment, the cannabinoid source includes a cannabis concentrate obtained by an extraction process from plant materials. Several extraction processes are known in the art.

[34] In a first option, one may extract cannabis plant materials using CO, extraction (under sub-critical or super-critical conditions) in order to obtain the cannabis concentrate.
Advantageously, in this option, the process is exempt of a winterization, evaporation or distillation step so as to retain some waxes and/or terpenes endogeneously present in the plant materials, which can operate as the herein described solubilizing aiding agent.

[35] In a second option, one may extract cannabis plant materials using polar solvent extraction (e.g., ethanol, butane, etc.). Advantageously, this process is also exempt of a winterization, evaporation or distillation step so as to retain some waxes and/or terpenes endogeneously present in the plant materials, which can operate as the herein described solubilizing aiding agent.

[36] With respect to these first and second options, when the preparation process is exempt of a winterization, evaporation or distillation step, the cannabis concentrate will still include some waxes and/or terpenes which are endogenously present in the cannabis plant material. The presence of these waxes and/or terpenes has the benefit of being able to operate as the herein described solubilizing aiding agent. The presence of such compounds in the concentrate, however, renders the concentrate too viscous for use in the vaping device and also imparts a dark color to the concentrate, which makes the cannabis concentrate less visually attractive for direct use in a vaping device which typically have clear liquid reservoir for holding the vaping oil.
In order to render the cannabis concentrate more suitable for use in the vaping device, the cannabis concentrate is diluted in carrier oil which is less opaque and less viscous than the cannabis concentrate. This cannabis concentrate will be referred to herein as being ready for mixing with the carrier oil.
In one embodiment, when the cannabis concentrate is obtained by extraction from cannabis plant materials through an extraction process exempt of a winterization step, the cannabis concentreate is, thus, exempt of a winterization solvent, e.g., ethanol. An objective manner to assess whether the cannabis concentrate is prepared from a process exempt of such winterization step is to measure the amount of winterization solvent (e.g., ethanol) present in the concentrate prior to mixing with the carrier oil. In one embodiment, the herein described concentrate is, thus, free from winterization solvent. Another practical way of assessing whether the concentrate is prepared from a process exempt of such winterization step is to determine whether the concentrate which is ready for for mixing with the carrier oil still includes endogenous plant waxes and/or terpenes which are typically removed through the winterization step. As such, the concentrate described herein has a high concentration of a cannabinoid, still includes plant waxes and is ready for mixing with the carrier oil for making cannabis oil for use in a vaping device.
[38] In a third option, one may include one or more purification steps after one of the above extraction steps, such as a winterization step, evaporation step or a distillation step. For example, US 7,700,368, US 2004/0049059 and US 2008/0167483, which are herein incorporated by reference in their entirety, each describes a process for extracting cannabinoids from cannabis plant material using CO, extraction followed by ethanol winterization to remove waxes. In another example US20160346339, which is incorporated by reference in its entirety, describes a process for extracting cannabinoids from cannabis plant material using solvent extraction followed by filtration, and evaporation of the solvent in a distiller to obtain a distillate.
Implementing these processes is said to result in a cannabinoid having a chromatographic purity of greater than 99%.
[39] In this third option, the endogenous waxes and/or terpenes are removed by the purification step(s) and one obtains a cannabinoid source which is depleted from the endogenous soubilizing aiding agent. Typically, such cannabinoid source can be in crystal form or in semi-solid form (highly viscous composition) such that it is not suitable for direct use in the vaping device. In order to make the cannabinoid source suitable for use in the vaping device requires dilution in carrier oil which is less viscous. In order to benefit from the herein described approach to using minimal amounts of carrier oil, a solubilizing agent is incorporated into the formulation to facilitate solubilization of the crystal or semi-solid cannabinoid source into the carrier oil, for example by adding the solubilizing aiding agent prior to, during or after adding the cannabinoid source to the minimal amount of carrier oil. Advantageously, plant waxes and/or terpenes can be incorporated to the cannabinoid source and carrier oil according to a desired wax / terpene profile, for example to mitnick a certain cannabis plant strain wax/terpene profile.
[40] One or more of the above discussed options may include a decarboxylation step performed prior to or after the extraction step. This decarboxylation step is optional in that at least some portion of the cannabinoid present in the cannabis vaping oil may be decarboxylated during use in the vaping device due to the high vaporization heat applied to the vaping oil in the device.

[41] Without being bound by any theory, the present inventors believe that omitting one or more of the typical purification steps performed when extracting a cannabinoid from a cannabis plant material is beneficial in that endogenous waxes and/or terpenes remaining in the cannabis concentrate extract may operate as a solubilizing aiding agent and assist in solubilizing the cannabinoid in the carrier oil. Alternatively, when one or more of the typical purification steps is performed when extracting a cannabinoid from a cannabis plant material, one may still reach the desired result by incorporating a solubilizing aiding agent into the mixture of cannabinoid and carrier oil may assist in solubilizing the cannabinoid in the carrier oil.
Ultimately, the presence of the solubilizing aiding agent translates into cannabis vaping oil that includes minimal amounts of carrier oil and, thus, higher concentration of the cannabinoid. In other words, cannabis vaping oil that incorporates the resulting mixture will have a higher cannabinoid concentration compared to cannabis vaping oil without the solubilizing aiding agent.
Cannabis Vaping Oil [42] The cannabis vaping oil of the present disclosure includes a high concentration of a cannabinoid. For example, the cannabis vaping oil can include, but without being limited to, at least 300 mg/ml, or at least 350 mg/ml, or at least 400 mg/ml, or at least 450 mg/ml, or at least 500 mg/ml, or at least 550 mg/ml, or at least 600 mg/ml, or at least 650 mg/ml, or more of the cannabinoid.
[43] The cannabis vaping oil may include more than one cannabinoid. In such case, the vaping oil may include relatively high concentrations of all such cannabinoids or, alternatively, of only one. In other words, the cannabis vaping oil may include a high concentration 300 mg/ml) of one cannabinoid and a low concentration 30 mg/ml) of another cannabinoid, or alternatively, the vaping oil may include a high concentration (? 300 mg/ml) of all cannabinoids contained therein.
[44] In some embodiments, the cannabis vaping oil includes tetrahydrocannabinol (THC).
[45] In some embodiments, the cannabis vaping oil includes cannabidiol (CBD).
[46] In some embodiments, the cannabis vaping oil includes more than one cannabinoid, e.g., THC and CBD.

[47] In one embodiment, the cannabis vaping oil includes a proportion of ?
40 wt.% of the cannabinoid source relative to the weight of carrier oil, such that the cannabis vaping oil has a high concentration of a cannabinoid. In a particular embodiment, the proportion of the cannabinoid source is < 70 wt.% relative to the weight of carrier oil, such that the cannabis vaping oil retains sufficient free-flowing liquid properties to afford ease of use with the vaping device.
[48] In one non-limiting embodiment, the cannabis vaping oil includes one or more carrier oil(s).
[49] In one non-limiting embodiment, the one or more carrier oil(s) is (are) of plant origin.
For example, but without being limited to, terpenes, essential oils, and the like, such as for example, d-limonene, Orange sweet (Citrus sinensis), b-myrcene, Pine (Pinus sylvestris), Fir (Abies siberica or Abies balsamea), Juniper Berry Ouniperus communis), lemon Lime Flavor, peppermint oil, and the like.
[50] In one non-limiting embodiment, the carrier oil includes a medium chain triglyceride (MCT).
[51] In one non-limiting embodiment, the carrier oil includes a mixture of MCT with another oil. For example, the carrier oil can include a mixture of peppermint oil and MCT in proportions such that the typical taste of peppermint oil is tamed down with the MCT.
Cartridge component of a vaping device [52] The cannabis oil of the present disclosure can be used in any suitable cartridge component of a vaping device.
[53] For example, Fig. 1A is a plan view of a non-limiting example of a cartridge 100 component of an electronic vaping device. A vaping device can also be referred to as a vaporizer, a vaporizer pen, a vape pen or an electronic or "e-" cigarette, for example.
The cartridge 100 includes a vapor outlet 50 at one end thereof, which includes a tip 40 and sidewalls 20 and 25, which could be sides or parts of the same cylindrical sidewall in some embodiments.
[54] The cartridge 100 further includes a liquid reservoir 60 for containing the cannabis oil.
The vapor outlet 50, in addition to sealing an end of an interior space of the liquid reservoir 60, also provides a mouth-piece portion through which a user can draw vapor from the electronic vaping device. The mouthpiece could be tapered, as shown, or otherwise shaped for a user's comfort. The present disclosure is not limited to any particular shape of the vapor outlet 50.
[55] The vapor outlet 50 could be made from one or more materials including metal, ceramic, wood, or a combination thereof. However, other materials could also or instead be used.
[56] The liquid reservoir 60 holds the vaporization substance prior to vaporization. The liquid reservoir 60 includes outer walls 10 and 15, which could be a single wall such as a cylindrical sidewall. The outer walls 10 and 15 of the liquid reservoir 60 could be made from one or more transparent or translucent materials, such as medical grade glass, in order to enable a user to visibly determine the quantity of vaporization substance in the chamber.
[57] The liquid reservoir 60 engages the vapor outlet 50, and could be coupled to the vapor outlet 50, via an engagement or connection at 116. A gasket or other sealing member could be provided between the liquid reservoir 60 and the vapor outlet 50 to seal the vaporization substance in the liquid reservoir 60.
[58] Although some liquid reservoir are "non-redoseable" (or sealable) and cannot be opened after initial filling, others are recloseable chambers in which the engagement at 116, between the vapor outlet 50 and the liquid reservoir 60, is releasable. For example, the vapor outlet 50 could be a cover that releasably engages the liquid reservoir 60 and seals a vaporization substance in the liquid reservoir 60, thereby preventing the vaporization substance from leaking out of the liquid reservoir 60. A releasable engagement could include, for example, a threaded engagement or other type of connection, or an abutment between the liquid reservoir 60 and the vapor outlet 50, without necessarily an actual connection between the chamber and the vapor outlet. Such a releasable engagement permits the vapor outlet 50 to be disengaged or removed from the liquid reservoir 60 so that the chamber can be cleaned, emptied, and/or filled with a vaporization substance, for example. The vapor outlet 50 could then re-engage with the liquid reservoir 60 to seal the vaporization substance inside the chamber.
[59] Fig. 1A also illustrates a stem 110 inside the liquid reservoir 60.
The stem 110 is a hollow tube or air channel through which vapor can be drawn into and through vapor outlet 50. The stem 110 may also be referred to as a central column, a central post, a chimney, a hose or a pipe.

Materials such as stainless steel, other metal alloys, plastics and ceramics could be used for stems such as the stem 110. The stem 110 couples the vapor outlet 50 via an engagement or connection (not shown). The stem 110 may include at its base one or more intake holes (not shown) having a suitable opening size, such as for example 1.2 or 1.6 mm.
[60] In one embodiment, screwing the vapor outlet 50 onto the stem 110 could also engage the vapor outlet 50 with the liquid reservoir 60, or similarly screwing the vapor outlet 50 onto the liquid reservoir 60 could also engage the vapor outlet 50 with the stem 110.
[61] Fig. 1B shows a battery compartment 200 that includes supplies power to the cartridge 100. The battery compartment 200 engages, and could also be coupled to the cartridge 100 via a female engagement 130 which receives a male thread 30 present at an end of the cartridge 100. In this embodiment, the engagement 130 and thread 30 is a releasable engagement.
However, in some embodiments, this could be a fixed connection. In some embodiments, the thread 30 may take the form of a 510 thread, which typically may include a connector having a length of 5 mm and having 10 threads. In the embodiment shown, the releasable engagement enables removal or disengagement of the battery compartment 200 from the cartridge 100 to permit recharging of the battery contained within the elongated body 110 of the battery compartment 200 or permuting the battery compartment 200 with another identical or different battery compartment 200'.
[62] The battery compartment 200 generally includes circuitry to supply power to the cartridge 100. For example, the battery compartment 200 could include electrical contacts that connect to corresponding electrical contacts with the battery. The battery compartment 200 could further include electrical contacts that connect to corresponding electrical contacts in the cartridge 100. The battery compartment 200 could reduce, regulate or otherwise control the power/voltage/current output from the battery. However, this functionality could also or instead be provided by the battery itself. The battery compartment 200 could be made from one or more materials including metals, plastics, elastomers and ceramics, for example, to carry or otherwise support other base components such as contacts and/or circuitry.
However, other materials could also or instead be used.
[63] The battery compartment 200 includes sidewalls 140 and 141, a bottom 142 and a button 144. The sidewalls 140 and 141, could be a single wall such as a cylindrical sidewall. The battery compartment 200 could include single-use batteries or rechargeable batteries such as lithium-ion batteries. The battery compartment 200 powers the vaporization device and allows powered components of the vaporization device, including at least the cartridge 100, to operate.
Other powered components could include, for example, one or more light-emitting diodes (LEDs), speakers or other indicators of device power status (on / off), device usage status (on when a user is drawing vapor), etc. In some embodiments, speakers and/or other audible indicators could produce long, short or intermittent "beep" sounds as a form of indicator of different conditions.
[64] As noted above, in some embodiments, the vapor outlet 50, the liquid reservoir 60, the stem 110, the battery compartment 200 are cylindrical in shape or otherwise shaped in a way such that sidewalls that are separately labeled in Fig. 1A and/or Fig. 1B could be formed by a single sidewall. In these embodiments, the sidewalls 140 and 141 represent sides of the same sidewall.
Similar comments apply to outer walls 10 and 15, and sidewalls 20 and 25, and other walls that are shown in the drawings and/or described herein. However, in general, vapor outlets, liquid reservoirs, stems, cartridges, battery compartments that are not cylindrical in shape are also contemplated. For example, these components could be rectangular, triangular, or otherwise shaped.
[65] It should be appreciated, that the example cartridge 100 and the example battery compartment 200 are solely for the purpose of illustration. Other embodiments are also contemplated. For example, the vaping device could be a multi-chamber device vape device or a pen-and-pod device as commercialized by PAX (e.g., the PAX EraTm).
Definitions [66] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by a person of ordinary skill in the art to which the present invention pertains. As used herein, and unless stated otherwise or required otherwise by context, each of the following terms shall have the definition set forth below.
[67] For the purpose of this specification, the expression "cannabinoid"
means a compound such as cannabigerolic acid (CBGA), cannabigerol (CBG), cannabigerol monomethylether (CBGM), cannabigerovarin (CBGV), cannabichromene (CBC), cannabichromevarin (CBCV), cannabidiol (CBD), cannabidiol rnonomethylether (CBDM), cannabidiol-C4 (CBD-C4), cannabidivarin (CBDV), cannabidiorcol (CBD-C1), delta-9-tetrahydrocannabinol (A9-THC), delta-9-tetrahydrocannabinolic acid A (THCA-A), delta-9-tetrahydrocannabionolic acid B
(THCA-B), delta-9-tetrahydrocannabinolic acid-C4 (THCA-C4), delta-9-tetrahydrocannabinol-C4, delta-9-tetrahydrocannabivarin (THCV), delta-9-tetrahydrocannabiorcol (THC-C1), delta-7-cis-iso tetrahydrocannabivarin, delta-8-tetrahydrocannabinol (A8-THC), cannabicyclol (CBL), cannabicyclovarin (CBLV), cannabielsoin (CBE), cannabinol (CBN), cannabinol methylether (CBNM), cannabinol-C4 (CBN-C4), cannabivarin (CBV), cannabinol-C2 (CBN-C2), cannabiorcol (CBN-C1), cannabinodiol (CBND), cannabinodivarin (CBVD), cannabitriol (CBT), 10-ethoxy-9hydroxy-delta-6a-tetrahydrocannabinol, 8,9-dihydroxy-delta-6a-tetrahydrocannabinol, cannabitriolvarin (CBTV), ethoxy-cannabitriolvarin (CBTVE), dehydrocannabifuran (DCBF), cannabifuran (CBF), cannabichromanon (CBCN), cannabicitran (CBT), 10-oxo-delta-6a-tetrahydrocannabionol (OTHC), delta-9-cis-tetrahydrocannabinol (cis-THC), 3,4,5,6-tetrahydro-7-hydroxy-alpha-alpha-2-trimethy1-9-n-propy1-2, 6-methano-2H-1-benzoxocin-5-methanol (OH-iso-HHCV), cannabiripsol (CBR), trihydroxy-delta-9-tetrahydrocannabinol (tri0H-THC), cannabinol propyl variant (CBNV), and derivatives thereof.
[68] For the purpose of this specification, the expressions "cannabidiol"
or "CBD" are generally understood to refer to one or more of the following compounds, and, unless a particular other stereoisomer or stereoisomers are specified, includes the compound "A2-cannabidiol." These compounds are: (1) A5-cannabidiol (2-(6-isopropeny1-3-methy1-5-cyclohexen-l-y1)-5-penty1-1,3-benzenediol); (2) A4-cannabidiol (2- (6-is oprop eny1-3 -methy1-4-cyclohex en-1-y1)-5-p enty1-1,3-b enz enediol) ; (3) A3- cannabidiol (2- (6-is oprop eny1-3-methy1-3-cyclo hexen-l-y1)-5-p enty1-1,3-b enz enediol); (4) A3,7-cannabidiol (2- (6-is opropeny1-3 -methylenecyclohex-1-y1) -5-p entyl-1,3 -b enz enediol); (5) A2- cannabidiol (2-(6-is oprop eny1-3 -methy1-2- cyclohex en-1-y1) -5-p enty1-1,3-b enz enediol) ; (6) -cannabidiol (2- (6-is oprop eny1-3-methyl-l-cyclohexen-l-y1)-5-pentyl-1,3-benzenediol); and (7) A6-cannabidiol (2-(6-isopropeny1-3-me thy1-6-cyclo hexen-l-y1)-5-p enty1-1,3-b enz enediol) .
[69] For the purpose of this specification, the expression "viscosity threshold" in reference to a cannabis vaping oil means the highest viscosity value at room temperature which remains suitable for use in a particular vaping device and allow proper use of that vaping device, e.g., for loading cannabis oil into the cartridge, properly feeding the cannabis oil to the heating element of the vaping device in order to vaporize one or more cannabinoid(s) while minimizing clogging of cartridge internal components, the viscosity of the cannabis oil may also assist with the performance of the vaping device such as by preventing or mininnizing leakage of the cannabis oil from the vaping device when not in use, and optimizing the performance of the vaping device and its delivery of the cannabinoid(s), and the like.
[70] For the purpose of this specification, the expression "cannabis concentrate" means an extract of a cannabis plant that concentrates a cannabinoid concentration by processing a cannabis plant to purify / isolate the cannabinoid. Typically, cannabis concentrates have a viscosity, which is too high for use in a vaping device.
[71] For the purpose of this specification, the expression "cannabis oil"
refers to an oil that contains anything referred to in item 1 or 3 of Schedule 1 of the Canadian Cannabis Act S.C.
2018, c.16 and that is in liquid faun at a temperature of 22 2 C.
[72] For the purpose of this specification, the term "medium chain triglycerides" or "MCT"
refers to triglycerides with two or three fatty acids having an aliphatic tail of 6-12 carbon atoms, i.e., medium-chain fatty acids (MCFAs). Rich food sources for commercial extraction of MCT
include palm kernel oil and coconut oil.
[73] The term "vegetable glycerin (VG)" is also known in the art as "monoglycerol" or "glycerol", generally obtained from plant and animal sources where it occurs as triglycerides.
[74] The term "polyethylene glycol (PEG)" is also known in the art as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight and refers to a compound with the chemical formula H¨ (0¨CH2¨CH2)¨ OH.
[75] The term "propylene glycol" is also known in the art as propane-1,2-diol and refers to a synthetic organic compound with the chemical formula C3H802.
[76] The term "of plant origin" is used interchangeably with "plant-based"
or with "plant-derived" and refers to a compound that is extracted or prepared from plant raw material. In one embodiment, this compound can be synthetic.
[77] The term "essential oil" does not mean indispensable as with the terms essential amino acid or essential fatty acid which are so called since they are nutritionally required by a given living organism, rather, the essential oil is "essential" in the sense that it contains the "essence of" or "at least a portion of the essence of" the plant's fragrance - the characteristic fragrance of the plant from which it is derived. Essential oils are generally extracted by distillation, often by using steam. Other processes include expression, solvent extraction, sfumatura, absolute oil extraction, resin tapping, wax embedding, and cold pressing. As such, in the present disclosure, essential oils are a concentrated hydrophobic liquid containing volatile aroma compounds from plants.
EXAMPLES
[78] The following examples describe some exemplary modes of making and practicing certain compositions that are described herein. It should be understood that these examples are for illustrative purposes only and are not meant to limit the scope of the disclosure.
Example 1¨ Cartridge [79] In accordance with a non-limiting example of the present disclosure, the inventors propose to use an A3-C full ceramic vape cartridge (Transpring Technology, USA) in order to test the cannabis oil of the present disclosure.
[80] The A3-C full ceramic vape cartridge has a full ceramic heating core, a 0.5 ml liquid reservoir, a resistance of 1.4/1.6S2, and 1.2 mm/1.6 mm oil intake hole size.
The liquid reservoir is made of medical grade glass and the rest of the cartridge is made of chrome-plated brass. The cartridge includes a 510 thread for coupling with the battery compartment.
Example 2¨ Battery compartment [81] In accordance with a non-limiting example of the present disclosure, the inventors propose to use an LO-A vape battery compartment (Transpring Technology, USA) in order to test with the A3-C cartridge of example 1.
[82] The LO-A vape battery has a capacity of 320 mAh, an output voltage of 2.6-4.0V with 3 adjustable voltages (green 2.6V, blue 3.3V, red 4.0V), a preheating output of 1.8V, a preheating time of 15 seconds, and 2 optional vaping ways: vape directly / vape with button-pressing.
Example 3¨ High Concentration Cannabis Vaping Oil [83] In accordance with a non-limiting example of the present disclosure, the inventors sought to test the amount of cannabinoid which could be solubili7ed in the carrier oil with a cannabinoid source in presence of a solubilizing aiding agent. In the present example, the cannabinoid source is a cannabis concentrate (CO2 extracted concentrate containing 2.14% THC
and 84.6 A CBD, which has not been winterized / distilled). In this example, the solubilizing aiding agent is an endogenous component present in the cannabis plant material, e.g., plant waxes and/or terpenes. The cannabinoid source was mixed with peppermint oil (50 ml) at room temperature without heating.

Cannabis Concentrate Amounts of CBD concentration Concentrate to added (g) cannabinoids (g) (mg/ml) oil (%) 1 0.868 15.10 2.00 2 1.735 30.20 4.00 3 2.603 45.30 6.00 4 3.470 60.40 8.00 4.338 75.50 10.00 6.15 5.335 92.86 12.30 5.31 4.606 80.18 10.62 8 6.940 120.80 16.00 9 7.808 135.90 18.00 8.675 150.99 20.00 17.88 15.511 269.98 35.76 17.350 301.99 40.00 29.34 25.452 443.02 58.68 40 34.700 603.98 80.00 50 43.375 754.97 100.00 63.86 55.399 964.25 127.72 95.72 83.037 1445.32 191.44 133.1 115.464 2009.74 266.20 190.76 165.484 2880.38 381.52 [84] The inventors discovered that by mixing a cannabinoid source with carrier oil in presence of the solubilizing aiding agent, a vaping oil having up to 2880 mg/ml CBD could be obtained, which still flows at room temperature and can still be pipetted in a pipette, i.e., meeting the desired characteristic that the mixture remains liquid at room temperature.
[85] The following table 2 sets out a number of additional cannabis oil formulation prepared by mixing various amounts of cannabis concentrate (CO, extracted concentrate containing 2.14% THC and 84.6 A CBD, which has not been winterized / distilled) and peppermint oil (100 ml) at room temperature without heating.

Cannabis Concentrate Amounts of CBD concentration Concentrate added (g) cannabinoids (g) (mg/ml) to oil (%) 20 17.35000 150.99 20.00 40 34.70000 301.99 40.00 50 43.37500 377.49 50.00 80 69.40000 603.98 80.00 [86] The inventors further optimized the relative proportions of cannabis concentrate to carrier oil in order to obtain a high concentration of cannabinoid while maintaining an optimum viscosity below the threshold viscosity (at which is intended to function the vaping device), which affords optimal use in a vaping device. The optimized proportions discovered by the inventors are in the range of 40 to 70 wt.% of cannabis concentrate containing endogenous solubilizing aiding agent to carrier oil.
[87] While the examples illustrated embodiments with cannabis concentrate having high levels of CBD and low levels of THC, it will be apparent to the person of skill that the same principles apply to a cannabis concentrate having different levels of these cannabinoids, or having different cannabinoids other than THC and/or CBD.
[88] Other examples of implementations will become apparent to the reader in view of the teachings of the present description and as such, will not be further described here.
[89] Note that titles or subtitles may be used throughout the present disclosure for convenience of a reader, but in no way these should limit the scope of the invention. Moreover, certain theories may be proposed and disclosed herein; however, in no way they, whether they are right or wrong, should limit the scope of the invention so long as the invention is practiced according to the present disclosure without regard for any particular theory or scheme of action.
[90] All references cited throughout the specification are hereby incorporated by reference in their entirety for all purposes.
[91] It will be understood by those of skill in the art that throughout the present specification, the term "a" used before a term encompasses embodiments containing one or more to what the term refers. It will also be understood by those of skill in the art that throughout the present specification, the term "comprising", which is synonymous with "including," "containing," or "characterized by," is inclusive or open-ended and does not exclude additional, un-recited elements or method steps.
[92] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.
[93] As used in the present disclosure, the terms "around", "about" or "approximately" shall generally mean within the error margin generally accepted in the art. Hence, numerical quantities given herein generally include such error margin such that the terms "around", "about" or "approximately" can be inferred if not expressly stated.
[94] Although various embodiments of the disclosure have been described and illustrated, it will be apparent to those skilled in the art in light of the present description that numerous modifications and variations can be made. The scope of the invention is defined more particularly in the appended claims.

Claims

CLAIMS:

1. Cannabis oil for use in a vaping device configured to evaporate the cannabis oil, the cannabis oil comprising a mixture of a cannabinoid source, a solubilizing aiding agent, and carrier oil, and at least 300 mg/ml of a cannabinoid.

2. The cannabis oil for vaping according to claim 1, wherein the cannabinoid source is a cannabis concentrate.

3. The cannabis oil for vaping according to claim 2, wherein the cannabis concentrate includes cannabidiol (CBD).

4. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 300 mg/ml of CBD.

5. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 650 mg/ml of CBD.

6. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 550 mg/ml of CBD.

7. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 450 mg/ml of CBD.

8. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 400 mg/nil of CBD.

9. The cannabis oil for vaping according to claim 3, wherein the cannabis oil includes >= 460 mg/nil of CBD.

10. The cannabis oil for vaping according to claim 2, wherein the cannabis concentrate includes tetrahydrocannabinol (THC).

11. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 300 mg/ml of THC.

12. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 650 mg/ml of THC.

13. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 550 mg/nil of THC.

14. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 450 mg/ml of THC.

15. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 400 mg/ml of THC.

16. The cannabis oil for vaping according to claim 10, wherein the cannabis oil includes >= 460 mg/nil of THC.

17. The cannabis oil for vaping according to any one of claims 3 to 9, wherein the cannabis oil further includes tetrahydrocannabinol (THC).

18. The cannabis oil for vaping according to claim 17, wherein the cannabis oil includes >= 30 mg/nil THC.

19. The cannabis oil for vaping according to claim 17, wherein the cannabis oil includes >= 25 mg/m1 of THC.

20. The cannabis oil for vaping according to claim 17, wherein the cannabis oil includes >= 20 mg/nil of THC.

21. The cannabis oil for vaping according to any one of claims 1 to 20, wherein the solubilizing aiding agent is a compound which is endogenously present in cannabis plant material.

22. The cannabis oil for vaping according to any one of claims 1 to 20, wherein the solubilizing aiding agent is a compound which is incorporated into the cannabis vaping oil.

23. The cannabis oil for vaping according to any one of claims 1 to 22, wherein the solubilizing aiding agent is a single compound.

24. The cannabis oil for vaping according to any one of claims 1 to 22, wherein the solubilizing aiding agent includes a blend of compounds.

25. The cannabis oil for vaping according to any one of claims 1 to 24, wherein the solubilizing aiding agent is selected from terpenes, cannabis plant waxes, and any combinations thereof.

26. The cannabis oil for vaping according to any one of claims 1 to 25, wherein the cannabinoid source includes cannabis concentrate in a proportion of 40 wt.%
relative to weight of the carrier oil.

27. The cannabis oil for vaping according to claim 26, the cannabis concentrate being in a proportion of 70 wt.% relative to weight of the carrier oil.

28. The cannabis oil for vaping according to any one of claims 1 to 27, wherein the carrier oil is an essential oil.

29. The cannabis oil for vaping according to any one of claims 1 to 27, wherein the carrier oil includes peppermint oil.

30. The cannabis oil for vaping according to any one of claims 1 to 27, wherein the carrier oil includes a medium chain triglyceride (MCT).

31. The cannabis oil for vaping according to any one of claims 1 to 27, wherein the carrier oil includes a medium chain triglyceride (MCT) and an essential oil.

32. The cannabis oil for vaping according to any one of claims 1 to 31, wherein the cannabinoid source includes a cannabis concentrate obtained by CO2 cannabis plant extraction.

33. Cannabis oil for use in a vaping device configured for feeding the cannabis oil to a heating element through a wick system contained in the vaping device, the cannabis oil comprising at least 300 mg/m1 of a cannabinoid and having a viscosity which is suitable for feeding the cannabis oil to the heating element.

34. The cannabis oil for vaping according to claim 33, comprising a mixture of a cannabis concentrate, a solubilizing aiding agent and a carrier oil.

35. The cannabis oil for vaping according to claim 34, wherein the cannabis concentrate includes cannabidiol (CBD).

36. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 300 mg/ml of CBD.

37. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 650 mg/ml of CBD.

38. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 550 mg/ml of CBD.

39. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 450 mg/nil of CBD.

40. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 400 mg/ml of CBD.

41. The cannabis oil for vaping according to claim 35, wherein the cannabis oil includes >= 460 mg/nal of CBD.

42. The cannabis oil for vaping according to claim 34, wherein the cannabis concentrate includes tetrahydrocannabinol (THC).

43. The cannabis oil for vaping according to claim 42, wherein the cannabis oil includes >= 300 mg/ml of THC.

44. The cannabis oil for vaping according to claim 42, wherein the cannabis oil includes >= 650 mg/nil of THC.

45. The cannabis oil for vaping according to claim. 42, wherein the cannabis oil includes >= 550 mg/ml of THC.

46. The cannabis oil for vaping according to claim 42, wherein the cannabis oil includes >= 450 mg/ml of THC.

47. The cannabis oil for vaping according to claim 42, wherein the cannabis oil includes >= 400 mg/ml of THC.

48. The cannabis oil for vaping according to claim 42, wherein the cannabis oil includes >= 460 mg/rial of THC.

49. The cannabis oil for vaping according to any one of claims 35 to 41, wherein the cannabis oil further includes tetrahydrocannabinol (THC).

50. The cannabis oil for vaping according to claim 49, wherein the cannabis oil includes >= 30 mg/ml THC.

51. The cannabis oil for vaping according to claim 49, wherein the cannabis oil includes >= 25 mg/m1 of THC.

52. The cannabis oil for vaping according to claim 49, wherein the cannabis oil includes >= 20 mg/nil of THC.

53. The cannabis oil for vaping according to any one of claims 34 to 52, wherein the solubilizing aiding agent is a compound which is endogenously present in cannabis plant material.

54. The cannabis oil for vaping according to any one of claims 34 to 52, wherein the solubilizing aiding agent is a compound which is incorporated into the cannabis vaping oil.

55. The cannabis oil for vaping according to any one of claims 34 to 54, wherein the solubilizing aiding agent is a single compound.

56. The cannabis oil for vaping according to any one of claims 34 to 54, wherein the solubilizing aiding agent includes a blend of compounds.

57. The cannabis oil for vaping according to any one of claims 34 to 56, wherein the solubilizing aiding agent is selected from terpenes, cannabis plant waxes, and any combinations thereof.

58. The cannabis oil for vaping according to any one of claims 34 to 57, wherein the cannabis oil includes cannabis concentrate in a proportion of >= 40 wt.% relative to weight of the carrier oil.

59. The cannabis oil for vaping according to claim 58, the cannabis concentrate being in a proportion of <= 70 wt.% relative to weight of the carrier oil.

60. The cannabis oil for vaping according to any one of claims 34 to 59, wherein the carrier oil is an essential oil.

61. The cannabis oil for vaping according to any one of claims 34 to 59, wherein the carrier oil includes peppermint oil.

62. The cannabis oil for vaping according to any one of claims 34 to 59, wherein the carrier oil includes a medium chain triglyceride (MCT).

63. The cannabis oil for vaping according to any one of claims 34 to 59, wherein the carrier oil includes a medium chain triglyceride (MCT) and an essential oil.

64. The cannabis oil for vaping according to any one of claims 34 to 63, wherein the cannabis concentrate is obtained by CO2 cannabis plant extraction.

65. A cannabis vaping oil comprising a cannabis concentrate comprising plant waxes, medium chain triglycerides (MCI), and >= 300 mg/ml of a cannabinoid.

66. The cannabis oil according to claim 65, further comprising peppermint oil.

67. A cartridge component of an electronic vaping device, comprising a liquid reservoir containing the cannabis oil of any one of claims 1 to 66, and a wick system, the cartridge being configured for feeding the cannabis oil to a heating element through the wick system.

68. The cartridge of claim 67, comprising a vapor outlet at a first end and a thread at an opposing end of the cartridge.

69. The cartridge of claim 68, the thread being configured for mating with a corresponding thread on an end of an elongated body portion of the vaping device for coupling the cartridge to the elongated body portion.

70. The cartridge of claim 69, the elongated body portion of the vaping device including a power supply.

71. The cartridge of any one of claims 68 to 70, wherein the thread is a 510 thread.

72. The cartridge of any one of claims 68 to 71, wherein the liquid reservoir includes at least a portion which is made of medical grade glass.

73. The cartridge of any one of claims 68 to 72, wherein the vapor outlet includes a mouthpiece.

74. The cartridge of claim 73, wherein the mouthpiece includes metal, ceramic, wood, or a combination thereof.

75. A cannabis concentrate for mixing with a carrier oil to make cannabis oil for use in a vaping device, the cannabis concentrate comprising a plant wax and being free of winterization ethanol.

76. The cannabis concentrate for mixing with the carrier oil to make cannabis oil for use in the vaping device according to claim 75, comprising tetrahydrocannabinol (THC), cannabidiol (CBD), or a combination thereof.

77. The cannabis concentrate for mixing with the carrier oil to make cannabis oil for use in the vaping device according to claim 75 or 76, comprising >= 70 wt.% of a cannabinoid.

78. A process for making a cannabis oil for use in a vaping device, comprising the following steps a) extraction of a cannabinoid and waxes from cannabis plant material with carbon dioxide to obtain an extract containing the cannabinoid and waxes, b) adding carrier oil to the extract containing the cannabinoid and waxes to make the cannabis oil, the carrier oil and extract being present in respective proportions so as to obtain cannabis oil containing >= 300 mg/ml of the cannabinoid.

79. Method of manufacturing cannabis vaping oil suitable for use in a vaping device, the vaping device being configured for using a vaping oil having a viscosity at room temperature below a threshold, the method comprising:
a) providing a cannabinoid source having a viscosity at room temperature which is above the threshold;
b) providing a carrier oil having a viscosity below the threshold at room temperature; and c) diluting the cannabinoid source with the carrier oil in presence of a solubilizing aiding agent to form a mixture, wherein the proportions of cannabinoid source and carrier oil are selected such that the mixture has a viscosity below the threshold and >= 300 mg/ml of a cannabinoid.

80. Cannabis oil for use in a vaping device configured to evaporate the cannabis oil, the cannabis oil comprising a mixture of a cannabinoid source and carrier oil, wherein the cannabinoid source is derived from a cannabis plant and includes a cannabinoid and a wax extracted from the cannabinoid plant, wherein the cannabis oil has at least 300 mg/ml of the cannabinoid.

81. The cannabis oil for vaping according to claim 80, wherein the cannabinoid source is a cannabis concentrate.

82. The cannabis oil for vaping according to claim 81, wherein the cannabis concentrate includes cannabidiol (CBD).

83. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 300 mg/ml of CBD.

84. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 650 mg/ml of CBD.

85. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 550 mg/ml of CBD.

86. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 450 mg/ml of CBD.

87. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 400 mg/ml of CBD.

88. The cannabis oil for vaping according to claim 82, wherein the cannabis oil includes >= 460 mg/ml of CBD.

89. The cannabis oil for vaping according to claim 82, wherein the cannabis concentrate includes tetrahydrocannabinol (THC).

90. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 300 mg/ml of THC.

91. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 650 mg/ml of THC.

92. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 550 mg/ml of THC.

93. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 450 mg/ml of THC.

94. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 400 mg/ml of THC.

95. The cannabis oil for vaping according to claim 89, wherein the cannabis oil includes >= 460 mg/ml of THC.

96. The cannabis oil for vaping according to any one of claims 82 to 88, wherein the cannabis oil further includes tetrahydrocannabinol (THC).

97. The cannabis oil for vaping according to claim 96, wherein the cannabis oil includes >= 30 mg/ml THC.

98. The cannabis oil for vaping according to claim 96, wherein the cannabis oil includes >= 25 mg/ml of THC.

99. The cannabis oil for vaping according to claim 96, wherein the cannabis oil includes >= 20 mg/ml of THC.

100. The cannabis oil for vaping according to any one of claims 81 to 99, wherein the was operates to increase a solubility of the cannabinoid in the carrier oil.

101. The cannabis oil for vaping according to any one of claims 81 to 100, wherein the cannabinoid source includes cannabis concentrate in a proportion of >=
40 wt.% relative to weight of the carrier oil.

102. The cannabis oil for vaping according to claim 101, the cannabis concentrate being in a proportion of 70 wt.% relative to weight of the carrier oil.

103. The cannabis oil for vaping according to any one of claims 81 to 102, wherein the carrier oil is an essential oil.

104. The cannabis oil for vaping according to any one of claims 81 to 103, wherein the carrier oil includes peppermint oil.

105. The cannabis oil for vaping according to any one of claims 81 to 103, wherein the carrier oil includes a medium chain triglyceride (MCT).

106. The cannabis oil for vaping according to any one of claims 81 to 103, wherein the carrier oil includes a medium chain triglyceride (MCT) and an essential oil.

107. The cannabis oil for vaping according to any one of claims 81 to 106, wherein the cannabinoid source includes a cannabis concentrate obtained by CO2 cannabis plant extraction.