CA3003305C - Decouverte iterative de neoepitopes et immunotherapie adaptative et procedes associes - Google Patents

Decouverte iterative de neoepitopes et immunotherapie adaptative et procedes associes

Info

Publication number
CA3003305C
CA3003305C CA3003305A CA3003305A CA3003305C CA 3003305 C CA3003305 C CA 3003305C CA 3003305 A CA3003305 A CA 3003305A CA 3003305 A CA3003305 A CA 3003305A CA 3003305 C CA3003305 C CA 3003305C
Authority
CA
Canada
Prior art keywords
neoepitopes
attribute
patient
neoepitope
location
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3003305A
Other languages
English (en)
Other versions
CA3003305A1 (fr
Inventor
Stephen Charles Benz
Kayvan Niazi
Patrick Soon-Shiong
Andrew Nguyen
Original Assignee
Nantomics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nantomics LLC filed Critical Nantomics LLC
Priority claimed from PCT/US2016/056668 external-priority patent/WO2017066339A1/fr
Publication of CA3003305A1 publication Critical patent/CA3003305A1/fr
Application granted granted Critical
Publication of CA3003305C publication Critical patent/CA3003305C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

La présente invention concerne des projets de traitement anticancéreux comprenant l'analyse récursive de néoépitopes spécifiques d'un patient, d'un cancer et d'un lieu issus de divers sites de biopsie d'un patient après traitement ou entre des cycles successifs d'immunothérapie et/ou de chimiothérapie pour informer davantage l'immunothérapie. L'analyse récursive comprend de préférence divers attributs de néoépitopes afin d'identifier des néoépitopes appropriés au traitement.
CA3003305A 2015-10-12 2016-10-12 Decouverte iterative de neoepitopes et immunotherapie adaptative et procedes associes Active CA3003305C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562240482P 2015-10-12 2015-10-12
US62/240,482 2015-10-12
PCT/US2016/056668 WO2017066339A1 (fr) 2015-10-12 2016-10-12 Découverte itérative de néoépitopes et immunothérapie adaptative et procédés associés

Publications (2)

Publication Number Publication Date
CA3003305A1 CA3003305A1 (fr) 2017-04-20
CA3003305C true CA3003305C (fr) 2025-08-12

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