CA2994751A1 - Antibody against glypican-3 and application thereof - Google Patents

Antibody against glypican-3 and application thereof Download PDF

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Publication number
CA2994751A1
CA2994751A1 CA2994751A CA2994751A CA2994751A1 CA 2994751 A1 CA2994751 A1 CA 2994751A1 CA 2994751 A CA2994751 A CA 2994751A CA 2994751 A CA2994751 A CA 2994751A CA 2994751 A1 CA2994751 A1 CA 2994751A1
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Prior art keywords
seq
antibody
chain variable
variable region
amino acid
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CA2994751A
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English (en)
French (fr)
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CA2994751C (en
Inventor
Huamao Wang
Bo Song
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Crage Medical Co Ltd
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Carsgen Therapeutics Ltd
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11344578B2 (en) 2017-04-19 2022-05-31 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
US11767362B1 (en) 2016-03-15 2023-09-26 Chugai Seiyaku Kabushiki Kaisha Methods of treating cancers using PD-1 axis binding antagonists and anti-GPC3 antibodies
US12466867B2 (en) 2018-02-21 2025-11-11 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11767362B1 (en) 2016-03-15 2023-09-26 Chugai Seiyaku Kabushiki Kaisha Methods of treating cancers using PD-1 axis binding antagonists and anti-GPC3 antibodies
US11344578B2 (en) 2017-04-19 2022-05-31 Board Of Regents, The University Of Texas System Immune cells expressing engineered antigen receptors
US12466867B2 (en) 2018-02-21 2025-11-11 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses thereof
US12473336B2 (en) 2018-02-21 2025-11-18 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses thereof

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