CA2976926C - Anticorps anti-pvrig et methodes d'utilisation - Google Patents

Anticorps anti-pvrig et methodes d'utilisation

Info

Publication number
CA2976926C
CA2976926C CA2976926A CA2976926A CA2976926C CA 2976926 C CA2976926 C CA 2976926C CA 2976926 A CA2976926 A CA 2976926A CA 2976926 A CA2976926 A CA 2976926A CA 2976926 C CA2976926 C CA 2976926C
Authority
CA
Canada
Prior art keywords
seq
cells
cpa
pvrig
set out
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2976926A
Other languages
English (en)
Other versions
CA2976926A1 (fr
Inventor
Mark White
Sandeep Kumar
Christopher Chan
Spencer Liang
Lance Stapleton
Andrew W. Drake
Yosi Gozlan
Iian Vaknin
Shirley Sameah-Greenwald
Liat Dassa
Zohar Tiran
Gad S. Cojocaru
Leonard Presta
Richard Theolis
Original Assignee
Compugen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Ltd filed Critical Compugen Ltd
Priority claimed from PCT/US2016/018809 external-priority patent/WO2016134333A1/fr
Publication of CA2976926A1 publication Critical patent/CA2976926A1/fr
Application granted granted Critical
Publication of CA2976926C publication Critical patent/CA2976926C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L’utilisation d’un anticorps anti-PVRIG est décrite, lequel anticorps active les lymphocytes T et/ou les lymphocytes NK pour traiter le cancer. Les anticorps anti-PVRIG sont aussi utilisés pour activer les lymphocytes T et/ou les lymphocytes NK d’un patient atteint du cancer. Des anticorps anti-PVRIG spécifiques, des méthodes de fabrication des anticorps anti-PVRIG et des acides nucléiques, des vecteurs d’expression et des cellules hôtes connexes sont aussi décrits.
CA2976926A 2015-02-19 2016-02-19 Anticorps anti-pvrig et methodes d'utilisation Active CA2976926C (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562118208P 2015-02-19 2015-02-19
US62/118,208 2015-02-19
US201562141120P 2015-03-31 2015-03-31
US62/141,120 2015-03-31
US201562235823P 2015-10-01 2015-10-01
US62/235,823 2015-10-01
PCT/US2016/018809 WO2016134333A1 (fr) 2015-02-19 2016-02-19 Anticorps anti-pvrig et méthodes d'utilisation

Publications (2)

Publication Number Publication Date
CA2976926A1 CA2976926A1 (fr) 2016-08-25
CA2976926C true CA2976926C (fr) 2025-12-02

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