CA2947218C - Systeme et methode de numerisation instantanee de lamelles de microscope - Google Patents

Systeme et methode de numerisation instantanee de lamelles de microscope Download PDF

Info

Publication number
CA2947218C
CA2947218C CA2947218A CA2947218A CA2947218C CA 2947218 C CA2947218 C CA 2947218C CA 2947218 A CA2947218 A CA 2947218A CA 2947218 A CA2947218 A CA 2947218A CA 2947218 C CA2947218 C CA 2947218C
Authority
CA
Canada
Prior art keywords
driver
scanning
focusing
stage
slide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2947218A
Other languages
English (en)
Other versions
CA2947218A1 (fr
Inventor
William Gelbart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Motic China Group Co Ltd
Original Assignee
Motic China Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Motic China Group Co Ltd filed Critical Motic China Group Co Ltd
Priority to CA2947218A priority Critical patent/CA2947218C/fr
Publication of CA2947218A1 publication Critical patent/CA2947218A1/fr
Application granted granted Critical
Publication of CA2947218C publication Critical patent/CA2947218C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

Linvention concerne des exemples dun système de numérisation automatisé. Le système de numérisation automatisé comprend une unité de mise au point avec un tube de focalisation et une tourelle raccordée au tube de focalisation de sorte que la tourelle portant au moins un objectif se déplace avec le tube de focalisation vers le haut et vers le bas dans une direction de focalisation. En raison dune inertie plus faible de la tourelle, le temps de réglage de lunité de mise au point est bien plus court que lorsque toute la tête (boîtier et tête de microscope) est déplacée vers le haut et vers le bas dans la direction de focalisation. Grâce au déplacement du tube de focalisation vers le haut et vers le bas, une pluralité dimages peut être capturée à diverses profondeurs de mise au point pour chaque champ de vision. Les images acquises sont ensuite traitées pour déterminer une image avec la meilleure mise au point et déterminer des caractéristiques spécifiques mises en image.
CA2947218A 2016-11-02 2016-11-02 Systeme et methode de numerisation instantanee de lamelles de microscope Active CA2947218C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2947218A CA2947218C (fr) 2016-11-02 2016-11-02 Systeme et methode de numerisation instantanee de lamelles de microscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2947218A CA2947218C (fr) 2016-11-02 2016-11-02 Systeme et methode de numerisation instantanee de lamelles de microscope

Publications (2)

Publication Number Publication Date
CA2947218A1 CA2947218A1 (fr) 2018-05-02
CA2947218C true CA2947218C (fr) 2018-09-04

Family

ID=62068369

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2947218A Active CA2947218C (fr) 2016-11-02 2016-11-02 Systeme et methode de numerisation instantanee de lamelles de microscope

Country Status (1)

Country Link
CA (1) CA2947218C (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109030371A (zh) * 2018-10-25 2018-12-18 赛恩斯科学仪器(广州)有限公司 一种自动化切片扫描装置及切片扫描仪
CN110133309A (zh) * 2019-05-07 2019-08-16 易普森智慧健康科技（深圳）有限公司 全自动检测设备
CN113533323A (zh) * 2020-04-16 2021-10-22 上海伯顿医疗设备有限公司 自动扫描显微平台
CN112611752A (zh) * 2020-12-09 2021-04-06 山东志盈医学科技有限公司 数字病理切片扫描仪载玻片的检测定位方法及装置
CN112859316A (zh) * 2020-12-30 2021-05-28 杭州德适生物科技有限公司 一种大通量显微镜玻片装载系统以及扫描方法

Also Published As

Publication number Publication date
CA2947218A1 (fr) 2018-05-02

Similar Documents

Publication Publication Date Title
CA2947218C (fr) Systeme et methode de numerisation instantanee de lamelles de microscope
US9201234B2 (en) Automated slide scanning system for a microscope
EP2993478B1 (fr) Dispositif et procédé de mise en antémémoire de coulissement
CA2928374C (fr) Systemes d'imagerie, cassettes et procedes d'utilisation de ceux-ci
US20060204072A1 (en) System for creating microscopic digital montage images
US10338365B2 (en) Slide storage, retrieval, transfer, and scanning system for a slide scanner
CN101910907A (zh) 用于可控地扫描细胞样本的方法和系统
EP2098900A1 (fr) Agencement de scanner et procédé de balayage optique d'un objet
CN108801942B (zh) 水稻分蘖计数的线阵激光成像方法
KR102010818B1 (ko) 혈구 이미지 촬상장치
CN111679420B (zh) 一种数字病理切片自动扫描系统及方法
US11428919B2 (en) Objective changing and focusing apparatus for microscopes, and microscope having such objective changing and focusing apparatus
AU2015201450B2 (en) Imaging systems, cassettes, and methods of using the same