CA2941460C - Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson - Google Patents
Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson Download PDFInfo
- Publication number
- CA2941460C CA2941460C CA2941460A CA2941460A CA2941460C CA 2941460 C CA2941460 C CA 2941460C CA 2941460 A CA2941460 A CA 2941460A CA 2941460 A CA2941460 A CA 2941460A CA 2941460 C CA2941460 C CA 2941460C
- Authority
- CA
- Canada
- Prior art keywords
- eev
- disease
- subject
- parkinson
- blood sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La présente description concerne des procédés dévaluation clinique de la maladie de Parkinson chez un sujet à laide de vésicules extracellulaires dérivées dérythrocyte comme biomarqueur.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2941460A CA2941460C (fr) | 2016-09-08 | 2016-09-08 | Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2941460A CA2941460C (fr) | 2016-09-08 | 2016-09-08 | Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2941460A1 CA2941460A1 (fr) | 2018-03-08 |
CA2941460C true CA2941460C (fr) | 2023-05-23 |
Family
ID=61557419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2941460A Active CA2941460C (fr) | 2016-09-08 | 2016-09-08 | Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2941460C (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021107155A1 (fr) * | 2019-11-29 | 2021-06-03 | 富士フイルム和光純薬株式会社 | Procédé d'aide au diagnostic de la maladie de parkinson, biomarqueur, kit de réactifs et dispositif |
CN112386679B (zh) * | 2020-11-18 | 2023-05-30 | 徐州医科大学 | 一种包载sigma-1受体的外泌体在制备抗抑郁药物中的应用 |
-
2016
- 2016-09-08 CA CA2941460A patent/CA2941460C/fr active Active
Also Published As
Publication number | Publication date |
---|---|
CA2941460A1 (fr) | 2018-03-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Shi et al. | Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease | |
US10914748B2 (en) | Erythrocyte-derived extracellular vesicles as a biomarker for clinically assessing Parkinson's disease | |
US20230408532A1 (en) | Erythrocyte-derived extracellular vesicles and proteins associated with such vesicles as biomarkers for parkinson's disease | |
Nielsen et al. | A flow cytometric method for characterization of circulating cell-derived microparticles in plasma | |
McMillin et al. | Direct measurement of free copper in serum or plasma ultrafiltrate | |
Cloke et al. | Characterization of a novel population of low-density granulocytes associated with disease severity in HIV-1 infection | |
Bester et al. | Viscoelastic and ultrastructural characteristics of whole blood and plasma in Alzheimer-type dementia, and the possible role of bacterial lipopolysaccharides (LPS) | |
Bucciarelli et al. | Circulating microparticles and risk of venous thromboembolism | |
Musante et al. | Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment | |
Petchakup et al. | Label-free leukocyte sorting and impedance-based profiling for diabetes testing | |
Herrmann et al. | Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation | |
CA2941460C (fr) | Vesicules extracellulaires derivees d'erythrocyte comme biomarqueur d'evaluation clinique de maladie de parkinson | |
Taha | Plasma versus serum for extracellular vesicle (EV) isolation: A duel for reproducibility and accuracy for CNS‐originating EVs biomarker analysis | |
KR20160129444A (ko) | 혈장 내 아밀로이드베타의 농도를 통해 알츠하이머병을 임상학적 및 병리학적으로 모니터링하는 방법 | |
Siwaponanan et al. | Enumeration and phenotyping of circulating microvesicles by flow cytometry and nanoparticle tracking analysis: Plasma versus serum | |
Pliyev et al. | Circulating CD35−/CD49d+ neutrophils in influenza virus infection patients | |
EP3128327A1 (fr) | Procédé de détection de l'expression de la protéine smn | |
Mazzucco et al. | Assessment of regulatory T cells in childhood immune thrombocytopenic purpura | |
US10527634B2 (en) | Diagnostic markers of cognitive impairments, kits and uses thereof | |
Gharishvandi et al. | Assessment of Neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for detection of renal impairment in hypertensive patients | |
Hesselink et al. | Fragile neutrophils in surgical patients: A phenomenon associated with critical illness | |
Chiva-Blanch et al. | Functional and cognitive decline is associated with increased endothelial cell inflammation and platelet activation: liquid biopsy of microvesicles in community-dwelling octogenarians | |
Ali et al. | Bengal macrothrombocytopenia is not totally an innocuous condition | |
JP2016070798A (ja) | ベーチェット病の判定を補助する方法、及びベーチェット病の活動性の評価を補助する方法 | |
Gironi et al. | Platelet glutamate uptake and Th1 cells inversely correlate in relapsing/remitting and in progressive multiple sclerosis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |
|
EEER | Examination request |
Effective date: 20210826 |