CA2941069C - Acides amines de cyclopropene et procedes - Google Patents

Acides amines de cyclopropene et procedes

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Publication number
CA2941069C
CA2941069C CA2941069A CA2941069A CA2941069C CA 2941069 C CA2941069 C CA 2941069C CA 2941069 A CA2941069 A CA 2941069A CA 2941069 A CA2941069 A CA 2941069A CA 2941069 C CA2941069 C CA 2941069C
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CA
Canada
Prior art keywords
amino acid
cyclopropene
group
polypeptide
trna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2941069A
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English (en)
Other versions
CA2941069A1 (fr
Inventor
Thomas Elliott
Original Assignee
United Kingdom Research and Innovation
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Publication date
Priority claimed from GB1404569.4A external-priority patent/GB2528227A/en
Application filed by United Kingdom Research and Innovation filed Critical United Kingdom Research and Innovation
Publication of CA2941069A1 publication Critical patent/CA2941069A1/fr
Application granted granted Critical
Publication of CA2941069C publication Critical patent/CA2941069C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

L'invention concerne un polypeptide comprenant un acide aminé ayant un groupe cyclopropène qui est joint à l'acide aminé par l'intermédiaire d'un groupe carbamate. De manière appropriée, le groupe cyclopropène est un cyclopropène 1,3-disubstitué tel qu'un 1,3-diméthyl-cyclopropène. De manière appropriée le groupe cyclopropène est présent sous forme de résidu d'un acide aminé lysine. L'invention concerne également des procédés de préparation desdits polypeptides. Un acide aminé comprenant un cyclopropène, ledit groupe cyclopropène étant joint au fragment acide aminé par l'intermédiaire d'un groupe carbamate est en outre décrit.
CA2941069A 2014-03-14 2015-03-10 Acides amines de cyclopropene et procedes Active CA2941069C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1404569.4A GB2528227A (en) 2014-03-14 2014-03-14 Cyclopropene amino acids and methods
GB1404569.4 2014-03-14
PCT/GB2015/050694 WO2015136265A1 (fr) 2014-03-14 2015-03-10 Acides aminés de cyclopropène et procédés

Publications (2)

Publication Number Publication Date
CA2941069A1 CA2941069A1 (fr) 2015-09-17
CA2941069C true CA2941069C (fr) 2026-05-12

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