CA2935432A1 - Dispositif de detection d'immuno-essai - Google Patents
Dispositif de detection d'immuno-essai Download PDFInfo
- Publication number
- CA2935432A1 CA2935432A1 CA2935432A CA2935432A CA2935432A1 CA 2935432 A1 CA2935432 A1 CA 2935432A1 CA 2935432 A CA2935432 A CA 2935432A CA 2935432 A CA2935432 A CA 2935432A CA 2935432 A1 CA2935432 A1 CA 2935432A1
- Authority
- CA
- Canada
- Prior art keywords
- test
- detection device
- pathogen
- marker
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 62
- 238000003018 immunoassay Methods 0.000 title abstract description 10
- 244000052769 pathogen Species 0.000 claims abstract description 76
- 239000012491 analyte Substances 0.000 claims abstract description 32
- 238000012360 testing method Methods 0.000 claims description 121
- 239000000523 sample Substances 0.000 claims description 76
- 230000001717 pathogenic effect Effects 0.000 claims description 59
- 239000003550 marker Substances 0.000 claims description 43
- 239000003446 ligand Substances 0.000 claims description 32
- 230000000717 retained effect Effects 0.000 claims description 2
- 244000005700 microbiome Species 0.000 description 24
- 239000008280 blood Substances 0.000 description 16
- 210000004369 blood Anatomy 0.000 description 16
- 241000894006 Bacteria Species 0.000 description 14
- 238000000034 method Methods 0.000 description 13
- 239000000243 solution Substances 0.000 description 12
- 208000015181 infectious disease Diseases 0.000 description 11
- 238000011534 incubation Methods 0.000 description 9
- 238000003556 assay Methods 0.000 description 7
- 108010074051 C-Reactive Protein Proteins 0.000 description 6
- 102100032752 C-reactive protein Human genes 0.000 description 6
- 239000000427 antigen Substances 0.000 description 5
- 102000036639 antigens Human genes 0.000 description 5
- 108091007433 antigens Proteins 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- 210000001124 body fluid Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 238000003752 polymerase chain reaction Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 108091023037 Aptamer Proteins 0.000 description 3
- 206010040047 Sepsis Diseases 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 239000003146 anticoagulant agent Substances 0.000 description 3
- 229940127219 anticoagulant drug Drugs 0.000 description 3
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 241000894007 species Species 0.000 description 3
- 241000233866 Fungi Species 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 238000009640 blood culture Methods 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 231100001261 hazardous Toxicity 0.000 description 2
- 230000002458 infectious effect Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
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- 235000015097 nutrients Nutrition 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
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- 239000007787 solid Substances 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 108090001008 Avidin Proteins 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 229920000089 Cyclic olefin copolymer Polymers 0.000 description 1
- 239000004713 Cyclic olefin copolymer Substances 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 238000002829 antibacterial sensitivity test Methods 0.000 description 1
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- 238000009534 blood test Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
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- 230000009977 dual effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
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- 239000007850 fluorescent dye Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000028709 inflammatory response Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
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- 235000016709 nutrition Nutrition 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
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- 238000007789 sealing Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2935432A CA2935432A1 (fr) | 2016-07-07 | 2016-07-07 | Dispositif de detection d'immuno-essai |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2935432A CA2935432A1 (fr) | 2016-07-07 | 2016-07-07 | Dispositif de detection d'immuno-essai |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2935432A1 true CA2935432A1 (fr) | 2018-01-07 |
Family
ID=60940354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2935432A Pending CA2935432A1 (fr) | 2016-07-07 | 2016-07-07 | Dispositif de detection d'immuno-essai |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2935432A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11325975B2 (en) | 2014-11-13 | 2022-05-10 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
-
2016
- 2016-07-07 CA CA2935432A patent/CA2935432A1/fr active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11325975B2 (en) | 2014-11-13 | 2022-05-10 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11325974B2 (en) | 2014-11-13 | 2022-05-10 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11339219B2 (en) | 2014-11-13 | 2022-05-24 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11591393B2 (en) | 2014-11-13 | 2023-02-28 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11629187B2 (en) | 2014-11-13 | 2023-04-18 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11634491B2 (en) | 2014-11-13 | 2023-04-25 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11643462B2 (en) | 2014-11-13 | 2023-05-09 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11649287B2 (en) | 2014-11-13 | 2023-05-16 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11718668B2 (en) | 2014-11-13 | 2023-08-08 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
US11753468B2 (en) | 2014-11-13 | 2023-09-12 | The Johns Hopkins University | Checkpoint blockade and microsatellite instability |
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Legal Events
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |
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EEER | Examination request |
Effective date: 20210527 |