CA2901772C

CA2901772C - Needleless connector with support member

Info

Publication number: CA2901772C
Application number: CA2901772A
Authority: CA
Inventors: Jonathan Yeh; Christopher J. Zollinger; George Michel Mansour; Matthew QUACH
Original assignee: CareFusion 303 Inc
Current assignee: CareFusion 303 Inc
Priority date: 2013-03-14
Filing date: 2014-02-21
Publication date: 2021-01-05
Anticipated expiration: 2034-02-21
Also published as: EP2968901B1; CN108355239B; EP3199199A1; ES2632114T3; US9089682B2; CA2901772A1; ES2950438T3; EP4218896A2; CN105209108A; ES2671481T3; EP4218896A3; EP3335757A1; AU2024201384A1; US11730944B2; EP3199199B1; CN108355239A; JP6744902B2; EP2777757B1; AU2021269422B2; AU2021269422A1

Abstract

Needleless connectors are described herein. A needleless connector includes a body, a valve element at least partially disposed within the body, and a base. The valve element includes a cylindrical portion having an outwardly extending flange at a distal end. The flange has a bottom surface with an outer area and an inner area. The base includes a rim having a top surface that is in contact with at least a portion of the outer area of the flange of the valve element, the rim defining a recess with a bottom surface distally separated from the top surface of the rim, and at least one support member extending from the rim into the recess so as to contact the inner portion of the bottom surface of the flange.

Description

NEEDLELESS CONNECTOR WITH SUPPORT MEMBER
Cross-references to Related Applications [0001] Not applicable.
BACKGROUND
Field

[0002] The present disclosure generally relates to connectors, and, in particular, to needleless connectors.
Description of the Related Art

[0003] Medical treatments often include the infusion of a medical fluid (e.g., a saline solution or a liquid medication) to patients using an intravenous (IV) catheter that is connected though an arrangement of flexible tubing and fittings, commonly referred to as an "IV
set," to a source of fluid, for example, an IV bag. Certain needleless connectors may be used in an IV set and may have a self-sealing port to prevent leakage of fluid when a mating medical implement is decoupled from such a needleless connector. Additionally, a needleless connector may include a mechanical valve, for example, a collapsible valve comprising a flexible material for providing the self-sealing port and controlling the flow of fluid within the IV set.

[0004] When a needleless connector is used in an IV set but not being accessed (i.e., a mating medical implement is not coupled to the self-sealing port), the needleless connector may be subjected to back pressure from the flow of fluid within the IV set. For example, back pressure can be caused by a patient's blood pressure, by an injection made at a different connector in the IV set, or by a pump utilized in the IV set. Back pressure applied to some needleless connectors may cause the seal of the self-sealing port to be breached. If the seal of a non-accessed needieless connector becomes breached due to back pressure, then some medical fluid from the IV set may undesirably accumulate in the neck area of the self-sealing port or be expelled from the system.

WO 2013/099261 Al is an intermediate document. It discloses a needleless connector. A
bottomed, cylindrical hollow elastic body that opens toward an outlet side of a drug solution flow path is accommodated and arranged in an accommodation section formed in a housing.
Furthermore, a middle protrusion is provided toward an inlet side of the drug solution flow path from a middle portion of a bottom wall of the hollow elastic body.
US 2011/0028914 Al discloses a collapsible valve comprising a first portion with at least one dimple in a side thereof, and a second portion, the second portion being narrower than the first portion and arranged along an axial dimension of the first portion, the second portion including a cut therein.
EP 2 075 032 Al discloses a cap assembly for use with a lock solution delivery device. The cap assembly includes a housing defining a receptacle and having an inlet end and an outlet end. A plunger is movable axially within the receptacle from a retracted position to an advanced position and is rotatably supported within the receptacle from a first position to a second position.
SUMMARY

[0005] The disclosed subject matter relates to connectors having support members for collapsible valves. In certain embodiments, there is described a needleless connector, comprising: a body; a valve element at least partially disposed within the body, the valve element comprising a cylindrical portion having an outwardly extending flange at a distal end, the flange having a bottom surface divided into an outer area and an inner area such that the outer area and the inner area are aligned, and a base comprising a rim having a top surface that is in contact with at least a portion of the outer area of the flange of the valve element, the rim defining a recess with a bottom surface distally separated from the top surface of the rim, and at least one support member extending from the rim laterally into the recess so as to contact the inner area of the bottom surface of the flange, the base further comprises an air channel extending from the bottom surface of the recess through the base to an ambient environment.

2a

[0006] In certain embodiments, there is described a needleless connector, comprising: a housing comprising proximal and distal ends, a body having a female fitting with a port at the proximal end, a base having a male fitting at the distal end, and an internal cavity; and a valve element disposed within the internal cavity and comprising a proximal portion having a smiley cut, a cylindrical portion coupled to a distal end of the proximal portion, and an outwardly extending flange coupled to the distal end of the cylindrical portion, the flange having a bottom surface divided into an outer area and an inner area such that the outer area and the inner area are aligned, wherein the base comprises a rim having a top surface that is in contact with at least a portion of the outer area of the bottom surface of the flange of the valve element, the rim defining a recess in the base, the recess having a bottom surface distally separated from the top surface of the rim, and a plurality of protrusions each extending from the rim into the recess so as to contact the inner area of the bottom surface of the flange, and the base further comprises an air channel extending from the bottom surface of the recess through the base to an ambient environment, wherein the proximal portion of the valve element blocks the port when the female fitting of the needleless connector is not mated with a coMpatible male connector.
[0006a] In a further aspect, there is described a needleless connector, comprising: a body; a valve element at least partially disposed within the body, the valve element comprising a cylindrical portion having an outwardly extending flange at a distal end, the flange having a bottom surface; and a base comprising a rim having a top surface that is in contact with at least a portion of the bottom surface of the flange of the valve element, the rim defining a recess with a bottom surface distally separated from the top surface of the rim, and at least one support member extending from the rim laterally into the recess and from the top surface of the rim over the bottom surface of the recess, the base further comprises an air passage extending from the bottom surface of the recess through the base to an ambient environment.
10006b1 In a further aspect, there is described a needleless connector comprising: a housing defining an internal cavity and a central longitudinal axis, the housing comprising, (i) a body section comprising a first port and an inner contact tab extending into the internal cavity, wherein a cross-sectional width of the internal cavity tapers along the inner contact tab 2b toward the first port, and (ii) a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising an upper wall axially separated from a lower wall by a valve mount rim extending between the upper wall and the lower wall, the upper wall and the lower wall being transverse to the central longitudinal axis; and a compressible valve comprising a valve wall and a flange, the flange comprising, an upper lip protruding radially outward from an outer surface of the valve wall, a flange rim transverse to the upper lip, and a lower lip extending radially inward from the flange rim, the flange rim retained between the valve mount rim and the inner contact tab when the compressible valve is coupled with the valve mount so that the compressible valve is disposed within at least a portion of the internal cavity.
10006c1 In a further aspect, there is described a needleless connector comprising: a housing defining an internal cavity and a central longitudinal axis, the housing comprising, a body section comprising a first port and an inner contact tab; and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section where a fluid flow path is defined between the first port and the second port, the valve mount comprising an upper wall axially separated from a lower wall by a valve mount rim extending between the upper wall and the lower wall, the upper wall and the lower wall being transverse to the central longitudinal axis; and a compressible valve comprising a valve wall and a flange, the flange comprising, an upper lip protruding radially outward from an outer surface of the valve wall, a flange rim transverse to the upper lip, and a lower lip extending radially inward from the flange rim, the flange rim retained between the valve mount rim and a portion of an inner surface of the inner contact tab that tapers toward the first port when the compressible valve is coupled with the valve mount so that the compressible valve is disposed within at least a portion of the internal cavity.
[0006d] In a further aspect, there is described a needleless connector comprising: a housing defining an internal cavity and a central longitudinal axis, the housing comprising: a body section comprising a first port and an inner surface having support columns and contact tabs, wherein the support columns are longitudinally aligned with the contact tabs, and the support columns and the contact tabs are spaced apart from adjacent support columns and contact 2c tabs to define a fluid flow channel therebetween, and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising a valve mount rim extending away from the central longitudinal axis; and a compressible valve comprising a valve wall and a flange protruding radially outward from an outer surface of the valve wall, the flange comprising an outer surface and an inner surface, wherein, when the compressible valve is coupled with the base section, the valve mount rim engages against the inner surface of the flange, and the contact tabs engage against the outer surface of the flange.
10006e1 In a further aspect, there is described a needleless connector comprising: a housing defining an internal cavity and a central longitudinal axis, the housing comprising: a body section comprising a first port and an inner surface having support columns and contact tabs, wherein the support columns are longitudinally aligned with the contact tabs, and the support columns and the contact tabs are spaced apart from adjacent support columns and contact tabs to define a fluid flow channel therebetween, and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising a valve mount rim; and a compressible valve comprising a valve wall and a flange protruding radially outward from an outer surface of the valve wall, the flange comprising an upper lip, a lower lip, and a flange rim, wherein, when the compressible valve is coupled with the base section, the fluid flow channel extends between an outer surface of the flange rim and the contact tabs.

[0007] It is understood that various configurations of the subject technology will become readily apparent to those skilled in the art from the disclosure, wherein various configurations of the subject technology are shown and described by way of illustration. As will be realized, the subject technology is capable of other and different configurations and its several details are capable of modification in various other respects, all without departing from the scope of the subject technology. Accordingly, the summary, drawings and detailed description are to be regarded as illustrative in nature and not as restrictive.

BRIEF DESCRIPTION OF THE DRAWINGS

[0008] The accompanying drawings, which are included to provide further understanding and are incorporated in and constitute a part of this specification, illustrate disclosed embodiments and together with the description serve to explain the principles of the disclosed embodiments.
In the drawings:

[0009] FIG. 1A-1B are cross-sections of a conventional needleless connector.

[0010] FIG. IC is a perspective view of the base of the conventional connector of FIG. 1A.

[0011] FIG. 1D is a cross-section of the conventional connector of FIG. IA
when mated with compatible male connector.

[0012] FIG. lE is an enlarged view of a portion of FIG. 1D.

[0013] FIG. IF is a cross-section of the conventional connector of FIG. 1A
when the conventional connector is in a fluidly connected, but non-accessed state.

[0014] FIG. 2 is an exploded view of an exemplary needleless connector, in accordance with various aspects of the present disclosure.

[0015] FIG. 3 is a top view of the base of FIG. 2, in accordance with various aspects of the present disclosure.

[0016] FIGS. 4-5 are top views of other embodiments of the base, in accordance with various aspects of the present disclosure.

[0017] FIG. 6A is a cut-away perspective view of the assembled needleless connector of FIG. 2, in accordance with various aspects of the present disclosure.

[0018] FIGS. 6B-6D are cut-away perspective views of the complete connector at locations shown in FIG. 6A, in accordance with various aspects of the present disclosure.

[0019] FIG. 7 is a cross-section of an exemplary needleless connector of FIG.
2 when the exemplary needleless connector is in a fluidly connected, but non-accessed state, in accordance with various aspects of the present disclosure.

DETAILED DESCRIPTION

[0020] The disclosed self-sealing, needleless connector incorporates a flexible, collapsible valve disposed within a body of the connector. A bottom surface of the collapsible valve is in contact with support members of a base that support the collapsible valve when back pressure is applied to the needleless connector in order to prevent deformation of the collapsible valve toward the base. By preventing deformation of the collapsible valve toward the base, the back pressure deforms the collapsible valve in a manner that further improves the seal of the needleless connector when in a non-accessed state.

[0021] The detailed description set forth below is intended as a description of various configurations of the subject technology and is not intended to represent the only configurations in which the subject technology may be practiced. The detailed description includes specific details for the purpose of providing a thorough understanding of the subject technology.
However, it will be apparent to those skilled in the art that the subject technology may be practiced without these specific details. In some instances, well-known structures and components are shown in block diagram form in order to avoid obscuring the concepts of the subject technology. Like components are labeled with identical element numbers for ease of understanding. Reference numbers may have letter suffixes appended to indicate separate instances of a common element while being referred to generically by the same number without a suffix letter.

[0022] While the following description is directed to the administration of medical fluid to a patient by a medical practitioner using the disclosed needleless connector, it is to be understood that this description is only an example of usage and does not limit the scope of the claims.
Various aspects of the disclosed needleless connectors may be used in any application where it is desirable to prevent a valve from breaching a primary seal when in the connector is in a non-accessed state.

[0023] The disclosed needleless connector overcomes several challenges discovered with respect to certain conventional connectors. One challenge with certain conventional needleless self-sealing connectors is that a primary seal may be breached when the self-sealing connectors are subjected to back pressure from the flow of fluid within an IV set.
Because such a breach of the primary seal may result in the malfunction of the connector and failure in the administration of the medical fluid, such a breach is undesirable.

[0024] Therefore, in accordance with the present disclosure, it is advantageous to provide a needleless connector as described herein that eliminates or substantially reduces potential back pressure-related problems within the needleless connector during use without unduly limiting an air channel of the needleless connector. The disclosed needleless connector provides a support member on a base that substantially prevents the flexible valve from extending into a recess of the base.

[0025] FIG. IA- 113 are cross-sections of a conventional needleless connector 100.
Connector 100 includes a housing 120, which has female luer fitting 101 at the proximal end, a base 130, which has male luer fitting 102 at the distal end, and a valve element 103. The valve element 103 sits inside housing portion 120 and on top of the base 130. The proximal portion of valve element 102 has a "smiley cut" 106. Air channels 172 pass from the internal cavity 104 of the valve element 103 through the base 130 into the open space around the male Luer fitting 102.
The valve element 103 has a shoulder 107 that continuously contacts a ridge 122 within the interior of the housing 120, when the needleless connector 100 is not being accessed (i.e., a mating medical implement is not coupled to the self-sealing port) to form a primary seal that prohibits fluid of the fluid flow channels 174 from exiting the needleless connector 100 through the female luer fitting 101.

[0026] The cross-section of FIG. 1B is taken perpendicular to the cross-section of FIG. l A. In this view, the two dimples 106 formed in an external surface of the valve element 103 are visible. Fluid flow channels 174 pass from a cavity 22 within the housing 120 through the base 130 to a flow passage 132 within the male Luer fitting 102.

[0027] FIG. 1C is a perspective view of the base 130 of the conventional connector 100 of FIG. IA. The base 130 has a rim 150 surrounding a recess 140 with a bottom surface 160. The valve base 105 of the valve element 102 (not shown in FIG. IC) fits over the rim 150. The entrances to the air channels 172 are visible within the cavity 140. The entrance to one of the fluid flow channels 174 is visible on the side of the base 130.

[0028] FIG. ID is a cross-section of the conventional connector 100 of FIG. IA
when mated with compatible male connector 20. In operation, when the female fitting 101 of the connector 100 is accessed by a male fitting 20, the valve element 103 is sufficiently elastic so that it can bend out of the way to allow fluid flow and then return to its original shape after the male fitting 20 is disconnected. The collapsible valve element 103 is shown in a collapsed position after insertion of the male connector 20 into female fitting 101.
Fluid can flow from the male connector 20 around the collapsed valve element 103 is into channels including the fluid flow channels 174 of the base 130 and into the male luer fitting 102 for exiting the connector 100. The valve base 105 of the valve element 103 deformed under the pressure of the male connector 20, with the deformation being described in greater detail with respect to FIG IE.

[0029] Connector 100 is a positive displacement device. When a new connection is made at the female fitting 101, the internal cavity 104 is reduced and the connector 100 draws fluid in either through the female fitting 101 or the male fitting 102 of the base 130 via the fluid channel 222.
When a disconnection is made at the female luer fitting 101, the connector 100 expels fluid from the fluid channel 222, effectively flushing the connector 100 and, if one of the lines attached to fittings 101 or 102 are connected to a patient, avoids drawing blood into the line.
100301 FIG. IF is a cross-section of the conventional connector 100 of FIG. lA
when the male connector 20 (shown in FIG. 1D) has been removed and back pressure 134 is applied to the valve element 103 from the fluid channel 222 fluidly connected to a line (not shown) attached to the male fitting 102 of the base 130. When back pressure 134 is applied within the interior of the housing 120, the generally cylindrical shape of the valve element 103 is deformed to a generally oval-tubular shape. A proximal force 136 and a distal force 138 result from the deformation of the valve element 103 due to its flexible, collapsible properties. If the distal force 138 substantially counteracts the proximal force 136, then the shoulder 107' may cease to contact the ridge 122 within the interior of the housing 120, thereby causing a breach of the primary seal of the needleless connector 100. As similarly discussed with respect to the force applied by the male connector 20 in FIG IC, the valve base 105 of the valve element 103 is deformed under the pressure of the distal force 138 caused by back pressure 134 of the fluid entering the flow passage 132, with the deformation being described in greater detail with respect to FIG 1E.
[0031] FIG. lE is an enlarged view of a portion of FIG. ID and FIG. IF. The compressive load from the male fitting 20 (see FIG. ID) or the distal force 138 caused by back pressure 134 (see FIG. 1F) is transferred by the wall of the valve element 103 to the valve base 105 and then into the rim 150. Due to the flexible nature of the valve element 103, however, the interior corner 110 of the valve base 105 may deform and protrude into the cavity 140 as seen in FIG.
1E.

30 [0032] An example of a needleless connector that eliminates or substantially reduces undesirable deformation of the valve element during use is now described.
100331 FIG. 2 is an exploded view of an exemplary needleless connector 200, in accordance with various aspects of the present disclosure. The connector 200 includes a body 220 defining an internal cavity 204 and having a female fitting 201, a flexible valve element 203 having a cylindrical portion with a flange 205 extending outward at a distal end of the cylindrical portion 204 and an interior volume 213, and a base 230. The base 230 has a rim 250 that defines a recess 240 with two air passages 272 passing from a recess 240 through the body 230 to the ambient environment around the male fitting (not visible in FIG. 2), and one or more support members 280 that extend from the rim 150 laterally into the recess 240. When assembled, a top surface of the rim 250 is in contact with the valve base or flange 105. The recess 240 has a bottom surface 260 that is distally separated from the top surface of the rim 250. Two passages 274 (only one visible in FIG. 2) pass through the base 230 and are configured similar to passages 174 in FIGS. 1B and 1C.
[0034] In certain embodiments, the base 230 comprises a polycarbonate material. However, the base 230 as well as the body 220 of the connector 100 may comprise one or more materials including, but not limited to, polyester, polyethylene, and/or other thermoplastics. Additionally, one or both of the base 230 and the body 220 may be clear or translucent, thereby enabling partial visibility of fluid within the connector 200. In certain embodiments, the flexible valve element 203 comprises a silicone.
[0035] In certain embodiments, the needleless connector 200 may have certain similar characteristics and functionality similar to that of the conventional connector 100. For example, in certain embodiments, the needleless connector 200 includes certain aspects that are different from the connector 100 such as a smaller overall length, smaller port diameter, smaller fluid path channels, smaller overall diameter, different valve operation, different materials composition, etc. For example, in certain embodiments, base section 230 is smaller than base 130. In this regard, certain embodiments derive a benefit from the base section having a support member.
100361 As illustrated, the recess 240 of the base 230 is aligned to interface with the interior volume 213 of the flexible valve element 203 upon assembly. Embodiments of the support members 280 provide a mechanism for eliminating or substantially reducing intrusion of the flexible valve element 203 into the recess 240. Various examples of the configuration of support members 280 are discussed with respect to FIGS. 3-5. When assembled, the flange 205 of the flexible valve element 203 is captured between the body 220 and base 230, as is discussed in greater detail with respect to FIG. 6.
[0037] FIG. 3 is a top view of the base 230 of FIG. 2, in accordance with various aspects of the present disclosure. In this example embodiment, six protrusions 282A-282F are disposed along portions of the rim 250 and longitudinally extend into recess 240. In certain embodiments, there may be more or fewer protrusions 280. In certain embodiments, the protrusions 282A-282F have rounded tips as shown in FIG. 3. In certain embodiments, the protrusions 282A-282F may have sharp corners or straight edges. One or more of the protrusions 282A-282F may be disposed over the bottom surface 260. In the example shown in FIG. 3, all six of the protrusions 282A-282F are fully over the bottom surface 260, i.e. no portion of the protrusions 282A-282F overhang either of the flow passages 272. In this regard, the protrusions 280A-280F are arranged such that the cross-sectional area of the air passage 272 is not reduced or obstructed while providing support for the flange 205 of the valve member 203. Obstructing or reducing the cross-sectional area of the air passage 272 could decrease the performance of the valve member 203 in certain embodiments, for example, when air is required to rapidly escape or enter the interior volume 213 of the valve member 203 while collapsing or expanding, respectively. In some embodiments, one or more protrusions 280 may extend partially or completely over one of the air passages 272. The support of the flange 205 that is provided by the protrusions 280A-280F is discussed in greater detail with respect to FIG.
6D.
[0038] FIGS. 4-5 are top views of other embodiments 231, 232 of the base, in accordance with various aspects of the present disclosure. FIG. 4 illustrates another example of a base 231 having protrusions 282A-282C disposed over a portion of rim 250 on one side of a center axis 301 and no protrusions on the other side of axis 301. Provision of protrusions 282A-282C on a single side may provide, for example, improved control of the collapse of the flexible valve element 203.
[0039] FIG. 5 illustrates another example of a base 232. According to certain embodiments, the base 232 comprises one or more support ribs 285A-285C. In this example, each of the ribs 285A-285C extends across the recess 240 from a first portion of the rim 250 to a second portion of the rim 250. In some embodiments, the ribs 285A-285C are the full height of rim 250 and continuous for the entire length of the respective ribs 285A-285C. In other embodiments, one or more of the ribs 285A-285C may have open segments proximal the bottom surface 260 to P2015,0045 WO N / 093100-0093 May 20, 2015 facility an air pathway across the bottom surface 260 between the two apertures 272. In certain embodiments, each rib 285A-285C may be integral with the wall 250 and/or bottom 260 of the base 230.
[0040] In some embodiments, the support members 280, for example the protrusions 282 of FIG. 3 and/or the ribs 285 of FIG. 5, may extend between 0,0254 cm (0.01 inches) and 0,381 cm (0.15 inches) above the rim 250. In certain embodiments, the support members 280 may extend 0,127 cm (0.05 inches) above the rim 250. In certain embodiments, the support members 280 may extend the same longitudinal length. In other embodiments, the support members 280 may have different longitudinal lengths. In certain embodiments, the support members 280 may have various portions that are recessed below, flush with, or raised above the top surface of the rim 250.
[0041] FIG. 6A is a cut-away perspective view of the assembled neecileless connector 200 of FIG. 2, in accordance with various aspects of the present disclosure. The flange 205 has engaged the rim 250 of base 230, and then the body 220 placed over the flexible valve element 203 and sealingly coupled to the body 230, thereby capturing a portion of the flange 205 between the body 220 and base 230. The various sections B-B, C-C, and D-D are shown in FIGS. 6B-6D, respectively. The top opening to one of the air channels 272 is visible adjacent to the bottom surface 260. This embodiment of valve element 203 has internal dimples 215 that extend over a portion of a circumference of the surface of the internal volume 213.
[0042] FIGS. 6B-6D are cut-away perspective views of the complete connector 200 at locations shown in FIG. 6A, in accordance with various aspects of the present disclosure. FIG. 6B is taken above the flange 205 and shows the cylindrical portion of the valve element 203 disposed within the body 220. The interior volume 213 is visible within the valve element 203 while fluid channels 222 arc visible as formed in the interior wall of body 220 and external to the valve element 203.
[0043] FIG. 6C depicts a cross-section taken at the bottom surface of the flange 205. The outer diameter of the flange 205 has extended radially outward while maintaining an inner diameter matching the interior volume 213. The lower portions of fluid channels 222 are visible and provide the fluid flow path around the flange 205. The dash-line circle 216 indicates a projection of the outer surface of the cylindrical portion 204 onto the cross-sectional surface. In P2015,0045 WON /093100-0093 May 20, 9a certain embodiments, the circle 216 divides the bottom surface of the flange 205 into an inner area 207A and an outer area 207B.

100441 FIG. 6D depicts a cross-section taken through the protrusions 280A-280F
just below the bottom surface of the flange 205. It can be seen how the protrusions 280A-280F
extend inward over the inner area 207A and past the inner diameter of the flange 205, thereby providing complete support to the flange 205 and preventing the deformation seen in the conventional connector 100, for example as shown in FIG. 1E. In certain embodiments, the protrusions 280A-280F may be aligned, or oriented in a defined relationship, with respect to the dimples 215 of the valve element 203. In certain embodiments, one or more of the protrusions 280A-280F may not extend past the inner diameter of the flange 205.
100451 Referring to FIG. 7, an exemplary needleless connector 200 is shown when the needleless connector 200 is in a fluidly connected, but non-accessed state. As illustrated, the needleless connector 200 is being subjected to back pressure 234 applied to the valve element 203 from the fluid channel 322 fluidly connected to a line (not shown) attached to the male fitting 202 of the base 230. The base 230 has protrusions 280A-280F that provide support the valve element 203, particularly the flange 205, when back pressure 234 is applied to the valve element 203 within the body 220. Thus, the protrusions 280A-280F of the base 230 eliminate or substantially prevent deformation of the flange 205 into the recess 240 of the base 230.
Therefore, in contrast with FIG. IF, a proximal force 236 caused by back pressure 234 will be increased and a distal force 238 will be eliminated or substantially reduced. Accordingly, movement of the valve element 203 will occur in the proximal direction toward the female fitting 201, thereby further improving the primary seal of the needleless connector 200 between a shoulder 307 of the valve element 203 and an interior ridge 323 of the body 220 when being subjected to back pressure 234 in the fluidly connected, but non-accessed state.
[0046] The present disclosure is provided to enable any person skilled in the art to practice the various aspects described herein. The disclosure provides various examples of the subject technology, and the subject technology is not limited to these examples.
Various modifications to these aspects will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other aspects.
100471 A reference to an element in the singular is not intended to mean "one and only one"
unless specifically so stated, but rather "one or more." Unless specifically stated otherwise, the term "some" refers to one or more. Pronouns in the masculine (e.g., his) include the feminine and neuter gender (e.g., her and its) and vice versa. Headings and subheadings. if any, are used for convenience only and do not limit the invention.

[0048] The word "exemplary" is used herein to mean "serving as an example or illustration."
Any aspect or design described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other aspects or designs. In one aspect, various alternative configurations and operations described herein may be considered to be at least equivalent.
[0049] A phrase such as an "aspect" does not imply that such aspect is essential to the subject technology or that such aspect applies to all configurations of the subject technology. A
disclosure relating to an aspect may apply to all configurations, or one or more configurations.
An aspect may provide one or more examples. A phrase such as an aspect may refer to one or more aspects and vice versa. A phrase such as an "embodiment" does not imply that such embodiment is essential to the subject technology or that such embodiment applies to all configurations of the subject technology. A disclosure relating to an embodiment may apply to all embodiments, or one or more embodiments. An embodiment may provide one or more examples. A phrase such an embodiment may refer to one or more embodiments and vice versa.
A phrase such as a "configuration" does not imply that such configuration is essential to the subject technology or that such configuration applies to all configurations of the subject technology. A disclosure relating to a configuration may apply to all configurations, or one or more configurations. A configuration may provide one or more examples. A
phrase such a configuration may refer to one or more configurations and vice versa.
[0050] In one aspect, unless otherwise stated, all measurements, values, ratings, positions, magnitudes, sizes, and other specifications that are set forth in this specification, including in the claims that follow, are approximate, not exact. In one aspect, they are intended to have a reasonable range that is consistent with the functions to which they relate and with what is customary in the art to which they pertain.
[0051] In one aspect, the term "coupled" or the like may refer to being directly coupled. In another aspect, the term "coupled" or the like may refer to being indirectly coupled.
[0052] Terms such as "top," "bottom," "front," "rear" and the like if used in this disclosure should be understood as referring to an arbitrary frame of reference, rather than to the ordinary gravitational frame of reference. Thus, a top surface, a bottom surface, a front surface, and a rear surface may extend upwardly, downwardly, diagonally, or horizontally in a gravitational frame of reference.

[0053] Various items may be arranged differently (e.g., arranged in a different order, or partitioned in a different way) all without departing from the scope of the subject technology. All structural and functional equivalents to the elements of the various aspects described throughout this disclosure that are known or later come to be known to those of ordinary skill in the art are expressly incorporated herein by reference and are intended to be encompassed by the claims. Moreover, nothing disclosed herein is intended to be dedicated to the public regardless of whether such disclosure is explicitly recited in the claims. No claim element is to be construed unless the element is expressly recited using the phrase "means for"
or, in the case of a method claim, the element is recited using the phrase "step for."
Furthermore, to the extent that the term "include," "have," or the like is used, such term is intended to be inclusive in a manner similar to the term "comprise" as "comprise" is interpreted when employed as a transitional word in a claim.
[0054] The claims are not intended to be limited to the aspects described herein, but is to be accorded the full scope consistent with the language claims and to encompass all legal equivalents.

Claims

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE PROPERTY
OF PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:

1. A needleless connector, comprising:
a body;
a valve element at least partially disposed within the body, the valve element comprising a cylindrical portion having an outwardly extending flange at a distal end, the flange having a bottom surface divided into an outer area and an inner area such that the outer area and the inner area are aligned, and a base comprising a rim having a top surface that is in contact with at least a portion of the outer area of the flange of the valve element, the rim defining a recess with a bottom surface distally separated from the top surface of the rim, and at least one support member extending from the rim laterally into the recess so as to contact the inner area of the bottom surface of the flange, the base further comprises an air channel extending from the bottom surface of the recess through the base to an ambient environment.

2. The needleless connector of claim 1, wherein the at least one support member extends past the inner area of the flange.

3. The needleless connector of claim 2, wherein the cylindrical portion of the valve element has an interior volume with an inner surface extending from the bottom surface of the flange; and the at least one support member extends past a projected location of the inner surface of the interior volume of the valve element.

4. The needleless connector of claim 1, wherein the at least one support member extends solely over the bottom surface and not over the air channel.

5. The needleless connector of claim 1, wherein a portion of the at least one support member extends over a portion of the air channel.

6. The needleless connector of claim 1, wherein the at least one support member comprises a plurality of protrusions each having a tip disposed at an innermost end.

7. The needleless connector of claim 6, wherein the plurality of protrusions are disposed solely on one side of a center axis that passes through a center of the recess and a center of the air channel.

8. The needleless connector of claim 6, wherein a first protrusion of the plurality of protrusions extends further inward than a second protrusion of the plurality of protrusions.

9. The needleless connector of claim 1, wherein the at least one support member comprises a plurality of ribs that each extend from a respective first point on the rim that is on one side of a center axis that passes through a center of the recess and a center of an air channel to a respective second point on the rim that is on the other side of the center axis.

10. The needleless connector of claim 1, wherein:
the connector has a proximal-distal axis, the proximal-distal axis having a proximal end at the body and a distal end at the base;
the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the at least one support member lies in a second plane that is perpendicular to and distally separated from the first plane.

11. The needleless connector of claim 1, wherein:
the base has a proximal-distal axis, the proximal-distal axis having a proximal end at the body and a distal end at the base;
the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the at least one support member lies in a second plane that is proximally separated from the first plane.

12. A needleless connector, comprising:

a housing comprising proximal and distal ends, a body having a female fitting with a port at the proximal end, a base having a male fitting at the distal end, and an internal cavity; and a valve element disposed within the internal cavity and comprising a proximal portion having a smiley cut, a cylindrical portion coupled to a distal end of the proximal portion, and an outwardly extending flange coupled to the distal end of the cylindrical portion, the flange having a bottom surface divided into an outer area and an inner area such that the outer area and the inner area are aligned, wherein the base comprises a rim having a top surface that is in contact with at least a portion of the outer area of the bottom surface of the flange of the valve element, the rim defining a recess in the base, the recess having a bottom surface distally separated from the top surface of the rim, and a plurality of protrusions each extending from the rim into the recess so as to contact the inner area of the bottom surface of the flange, and the base further comprises an air channel extending from the bottom surface of the recess through the base to an ambient environment, wherein the proximal portion of the valve element blocks the port when the female fitting of the needleless connector is not mated with a compatible male connector.

13. The needleless connector of claim 12, wherein the plurality of protrusions extend past the inner area of the flange.

14. The needleless connector of claim 12, wherein the plurality of protrusions extends solely over the bottom surface and not over the air channel.

15. The needleless connector of claim 12, wherein the plurality of protrusions are disposed solely on one side of a center axis that passes through a center of the recess and a center of the air channel.

16. The needleless connector of claim 12, wherein:
the base has a proximal-distal axis, the proximal-distal axis being defined by the proximal and distal ends;

the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the plurality of protrusions lies in a second plane that is perpendicular to and distally separated from the first plane.

17. The needleless connector of claim 12, wherein:
the base has a proximal-distal axis, the proximal-distal axis being defined by the proximal and distal ends;
the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the plurality of protrusions lies in a second plane that is perpendicular to and proximally separated from the first plane.

18. A needleless connector, comprising:
a body;
a valve element at least partially disposed within the body, the valve element comprising a cylindrical portion having an outwardly extending flange at a distal end, the flange having a bottom surface; and a base comprising a rim having a top surface that is in contact with at least a portion of the bottom surface of the flange of the valve element, the rim defining a recess with a bottom surface distally separated from the top surface of the rim, and at least one support member extending from the rim laterally into the recess and from the top surface of the rim over the bottom surface of the recess, the base further comprises an air passage extending from the bottom surface of the recess through the base to an ambient environment.

19. The needleless connector of Claim 18, wherein the at least one support member contacts the bottom surface of the flange.

20. The needleless connector of Claim 18, wherein the bottom surface of the flange comprises an inner area and an outer area, and wherein the at least one support member contacts inner area.

21. The needleless connector of Claim 20, wherein the at least one support member extends past an inner diameter of the flange, and wherein the at least one support member does not extend over the air passage.

22. The needleless connector of Claim 18, wherein the cylindrical portion of the valve element has an interior volume with an inner surface extending from the bottom surface of the flange.

23. The needleless connector of Claim 22, wherein the at least one support member extends past a projected location of the inner surface of the interior volume of the valve element.

24. The needleless connector of Claim 22, wherein the valve element comprises an internal dimple that extends over a portion of a circumference of the inner surface of the interior volume.

25. The needleless connector of Claim 18, wherein the at least one support member comprises a plurality of protrusions.

26. The needleless connector of Claim 25, wherein the plurality of protrusions are disposed solely on one side of a center axis that passes through a center of the recess and a center of the air passage.

27. The needleless connector of Claim 25, wherein the plurality of protrusions do not extend across a center axis that passes through a center of the recess and a center of the air passage.

28. The needleless connector of Claim 25, wherein a first protrusion of the plurality of protrusions extends further inward than a second protrusion of the plurality of protrusions.

29. The needleless connector of Claim 18, wherein:

the base has a proximal-distal axis, the proximal-distal axis having a proximal end at the body and a distal end at the base;
the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the at least one support member lies in a second plane that is distally separated from the first plane.

30. The needleless connector of Claim 18, wherein:
the base has a proximal-distal axis, the proximal-distal axis having a proximal end at the body and a distal end at the base;
the top surface of the rim lies on a first plane that is perpendicular to the proximal-distal axis; and a portion of a top surface of the at least one support member lies in a second plane that is proximally separated from the first plane.

31. The needleless connector of Claim 30, wherein the top surface of the at least one support member is proximally separated from the first plane by a distance of about 0.01 to 0.15 inch (0.25 to 3.81 mm).

32. The needleless connector of Claim 30, wherein the top surface of the at least one support member is proximally separated from the first plane by a distance of 0.05 inch (1.27 mm).

33. A needleless connector comprising:
a housing defining an internal cavity and a central longitudinal axis, the housing comprising, (i) a body section comprising a first port and an inner contact tab extending into the internal cavity, wherein a cross-sectional width of the internal cavity tapers along the inner contact tab toward the first port, and (ii) a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising an upper wall axially separated from a lower wall by a valve mount rim extending between the upper wall and the lower wall, the upper wall and the lower wall being transverse to the central longitudinal axis; and a compressible valve comprising a valve wall and a flange, the flange comprising, an upper lip protruding radially outward from an outer surface of the valve wall, a flange rim transverse to the upper lip, and a lower lip extending radially inward from the flange rim, the flange rim retained between the valve mount rim and the inner contact tab when the compressible valve is coupled with the valve mount so that the compressible valve is disposed within at least a portion of the internal cavity.

34. The needleless connector of Claim 33, wherein the flange rim tapers toward the first port.

35. The needleless connector of Claim 33, wherein the lower lip reduces in cross-sectional thickness as the lower lip extends radially inward from the flange rim.

36. The needleless connector of Claim 35, wherein the lower lip reduces in cross-sectional thickness at an angle of approximately 9 degrees relative to a plane transverse to the flange rim.

37. The needleless connector of Claim 33, wherein an interference fit between the inner surface of the inner contact tab and the flange rim creates a radial force substantially orthogonal to the central longitudinal axis to secure the flange rim between the valve mount rim and the inner surface of the housing.

38. The needleless connector of Claim 33, wherein the valve mount rim extends from the upper wall toward the bottom of the base section.

39. The needleless connector of Claim 33, wherein the valve wall comprises a first dimple and a second dimple formed in an internal surface.

40. The needleless connector of Claim 39, wherein the central longitudinal axis of the housing is defined by a coaxial arrangement of the first port and the second port, and a shape of at least one of the first dimple or the second dimple is formed with respect to an offset axis parallel to the central longitudinal axis.

41. The needleless connector of Claim 33, wherein the top of the base comprises a recess.

42. The needleless connector of Claim 41, wherein support members extend laterally inward from an inner surface of the valve mount, and span from the upper wall to a bottom surface of the recess.

43. The needleless connector of Claim 33, wherein the body comprises an inner support column.

44. A needleless connector comprising:
a housing defining an internal cavity and a central longitudinal axis, the housing comprising, a body section comprising a first port and an inner contact tab;
and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section where a fluid flow path is defined between the first port and the second port, the valve mount comprising an upper wall axially separated from a lower wall by a valve mount rim extending between the upper wall and the lower wall, the upper wall and the lower wall being transverse to the central longitudinal axis; and a compressible valve comprising a valve wall and a flange, the flange comprising, an upper lip protruding radially outward from an outer surface of the valve wall, a flange rim transverse to the upper lip, and a lower lip extending radially inward from the flange rim, the flange rim retained between the valve mount rim and a portion of an inner surface of the inner contact tab that tapers toward the first port when the compressible valve is coupled with the valve mount so that the compressible valve is disposed within at least a portion of the internal cavity.

45. The needleless connector of Claim 44, wherein the flange rim tapers toward the first port.

46. The needleless connector of Claim 44, wherein the lower lip reduces in cross-sectional thickness as the lower lip extends radially inward from the flange rim.

47. The needleless connector of Claim 46, wherein the lower lip reduces in cross-sectional thickness at an angle of approximately 9 degrees relative to a plane transverse to the flange rim.

48. The needleless connector of Claim 44, wherein an interference fit between the inner contact tab and the flange rim creates a radial force substantially orthogonal to the central longitudinal axis to secure the flange rim between the valve mount rim and the inner contact tab.

49. The needleless connector of Claim 44, wherein the valve mount rim extends from the upper wall toward the bottom of the base section.

50. The needleless connector of Claim 44, wherein the valve wall comprises a first dimple and a second dimple formed in an internal surface.

51. The needleless connector of Claim 50, wherein the central longitudinal axis of the housing is defined by a coaxial arrangement of the first port and the second port, and a shape of at least one of the first dimple or the second dimple is formed with respect to an offset axis parallel to the central longitudinal axis.

52. The needleless connector of Claim 44, wherein the body comprises an inner support column.

53. A needleless connector comprising:
a housing defining an internal cavity and a central longitudinal axis, the housing comprising:
a body section comprising a first port and an inner surface having support columns and contact tabs, wherein the support columns are longitudinally aligned with the contact tabs, and the support columns and the contact tabs are spaced apart from adjacent support columns and contact tabs to define a fluid flow channel therebetween, and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising a valve mount rim extending away from the central longitudinal axis; and a compressible valve comprising a valve wall and a flange protruding radially outward from an outer surface of the valve wall, the flange comprising an outer surface and an inner surface, wherein, when the compressible valve is coupled with the base section, the valve mount rim engages against the inner surface of the flange, and the contact tabs engage against the outer surface of the flange.

54. The needleless connector of Claim 53, wherein the flange comprises a channel that extends into the inner surface of the flange, toward the outer surface of the flange.

55. The needleless connector of Claim 53, wherein the valve wall comprises a first dimple and a second dimple formed in an internal surface.

56. The needleless connector of Claim 53, wherein base section comprises a recess between the valve mount and the second port.

57. The needleless connector of Claim 56, wherein support members extend laterally inward from the valve mount into the recess.

58. The needleless connector of Claim 53, wherein the valve mount rim extends from an upper wall of the valve mount toward the bottom of the base section.

59. The needleless connector of Claim 53, wherein a cross-sectional width of the internal cavity along the contact tabs is greater than a cross-sectional width of the internal cavity along the support columns.

60. The needleless connector of Claim 53, wherein the base section comprises a fluid passage extending through an outer surface of the base section, between the valve mount and the bottom of the base section, and wherein the fluid passage extends through the second port.

61. A needleless connector comprising:
a housing defining an internal cavity and a central longitudinal axis, the housing comprising:

a body section comprising a first port and an inner surface having support columns and contact tabs, wherein the support columns are longitudinally aligned with the contact tabs, and the support columns and the contact tabs are spaced apart from adjacent support columns and contact tabs to define a fluid flow channel therebetween, and a base section comprising a valve mount at a top of the base section and a second port at a bottom of the base section, the valve mount comprising a valve mount rim; and a compressible valve comprising a valve wall and a flange protruding radially outward from an outer surface of the valve wall, the flange comprising an upper lip, a lower lip, and a flange rim, wherein, when the compressible valve is coupled with the base section, the fluid flow channel extends between an outer surface of the flange rim and the contact tabs.

62. The needleless connector of Claim 61, wherein the lower lip is spaced apart from the upper lip.

63. The needleless connector of Claim 61, wherein a channel is formed between an inner surface of the upper lip and an inner surface of the lower lip.

64. The needleless connector of Claim 61, wherein a cross-sectional width of the outer surface of the flange rim tapers from the lower lip toward the upper lip.

65. The needleless connector of Claim 61, wherein a height of the lower lip decreases from the flange rim toward the central longitudinal axis.

66. The needleless connector of Claim 61, wherein when the compressible valve is coupled with the base section, the flange rim is compressed between the valve mount and the contact tabs.

67. The needleless connector of Claim 61, wherein the valve wall comprises a first dimple and a second dimple formed in an internal surface.

68. The needleless connector of Claim 61, wherein base section comprises a recess between the valve mount and the second port.

69. The needleless connector of Claim 68, wherein support members extend laterally inward from the valve mount into the recess.

70. The needleless connector of Claim 69, wherein the support members extend between an upper wall of the valve mount and a bottom surface of the recess.

71. The needleless connector of Claim 61, wherein the valve mount rim extends from an upper wall of the valve mount toward the bottom of the base section.

72. The needleless connector of Claim 61, wherein a cross-sectional width of the internal cavity along the contact tabs is greater than a cross-sectional width of the internal cavity along the support columns.