CA2833701A1 - Protein kinase inhibitors - Google Patents
Protein kinase inhibitors Download PDFInfo
- Publication number
- CA2833701A1 CA2833701A1 CA2833701A CA2833701A CA2833701A1 CA 2833701 A1 CA2833701 A1 CA 2833701A1 CA 2833701 A CA2833701 A CA 2833701A CA 2833701 A CA2833701 A CA 2833701A CA 2833701 A1 CA2833701 A1 CA 2833701A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- mmol
- kinase
- pharmaceutically acceptable
- protein kinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/17—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and doubly-bound oxygen atoms bound to the same acyclic carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
- C07C255/25—Aminoacetonitriles
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
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- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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- Oncology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2833701A CA2833701A1 (en) | 2013-11-19 | 2013-11-19 | Protein kinase inhibitors |
| TW103139934A TW201542554A (zh) | 2013-11-19 | 2014-11-18 | 蛋白質激酶抑制劑 |
| EP14863267.2A EP3071572A4 (en) | 2013-11-19 | 2014-11-19 | Protein kinase inhibitors |
| KR1020167016033A KR20160078504A (ko) | 2013-11-19 | 2014-11-19 | 단백질 키나제 저해제 |
| CN201480068293.5A CN105829313A (zh) | 2013-11-19 | 2014-11-19 | 蛋白激酶抑制剂 |
| JP2016531021A JP2016537367A (ja) | 2013-11-19 | 2014-11-19 | プロテインキナーゼ阻害剤 |
| CA2929881A CA2929881A1 (en) | 2013-11-19 | 2014-11-19 | Protein kinase inhibitors |
| RU2016123855A RU2016123855A (ru) | 2013-11-19 | 2014-11-19 | Ингибиторы протеинкиназы |
| US15/037,613 US20160289236A1 (en) | 2013-11-19 | 2014-11-19 | Protein Kinase Inhibitors |
| PCT/CA2014/000836 WO2015074135A1 (en) | 2013-11-19 | 2014-11-19 | Protein kinase inhibitors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2833701A CA2833701A1 (en) | 2013-11-19 | 2013-11-19 | Protein kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2833701A1 true CA2833701A1 (en) | 2015-05-19 |
Family
ID=53178740
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2833701A Abandoned CA2833701A1 (en) | 2013-11-19 | 2013-11-19 | Protein kinase inhibitors |
| CA2929881A Abandoned CA2929881A1 (en) | 2013-11-19 | 2014-11-19 | Protein kinase inhibitors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2929881A Abandoned CA2929881A1 (en) | 2013-11-19 | 2014-11-19 | Protein kinase inhibitors |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160289236A1 (OSRAM) |
| EP (1) | EP3071572A4 (OSRAM) |
| JP (1) | JP2016537367A (OSRAM) |
| KR (1) | KR20160078504A (OSRAM) |
| CN (1) | CN105829313A (OSRAM) |
| CA (2) | CA2833701A1 (OSRAM) |
| RU (1) | RU2016123855A (OSRAM) |
| TW (1) | TW201542554A (OSRAM) |
| WO (1) | WO2015074135A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016187723A1 (en) * | 2015-05-27 | 2016-12-01 | Pharmascience Inc. | Inhibitors of the tec kinase enzyme family |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10722484B2 (en) | 2016-03-09 | 2020-07-28 | K-Gen, Inc. | Methods of cancer treatment |
| EP3492471B1 (en) * | 2016-08-17 | 2020-12-02 | Shenzhen TargetRx, Inc. | Fused bicyclic compound for inhibiting activity of tyrosine kinase |
| FR3075794A1 (fr) | 2017-12-21 | 2019-06-28 | Galderma Research & Development | Nouveaux composes inhibiteurs de mtor |
| FR3075795A1 (fr) | 2017-12-21 | 2019-06-28 | Galderma Research & Development | Nouveaux composes inhibiteurs de mtor |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3176297A (en) * | 1996-06-25 | 1998-01-14 | Novartis Ag | Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof |
| HK1039326A1 (zh) * | 1998-09-18 | 2002-04-19 | Abbott Gmbh & Co. Kg | 4氨基吡咯并嘧啶作为激酶抑制剂 |
| WO2001019828A2 (en) * | 1999-09-17 | 2001-03-22 | Basf Aktiengesellschaft | Kinase inhibitors as therapeutic agents |
| ES2403546T3 (es) * | 2006-11-03 | 2013-05-20 | Pharmacyclics, Inc. | Sonda de actividad de la tirosina-cinasa de Bruton y procedimiento de utilización |
| CA2760174A1 (en) * | 2011-12-01 | 2013-06-01 | Pharmascience Inc. | Protein kinase inhibitors and uses thereof |
| CA2782774A1 (en) * | 2012-07-06 | 2014-01-06 | Pharmascience Inc. | Protein kinase inhibitors |
-
2013
- 2013-11-19 CA CA2833701A patent/CA2833701A1/en not_active Abandoned
-
2014
- 2014-11-18 TW TW103139934A patent/TW201542554A/zh unknown
- 2014-11-19 US US15/037,613 patent/US20160289236A1/en not_active Abandoned
- 2014-11-19 CA CA2929881A patent/CA2929881A1/en not_active Abandoned
- 2014-11-19 RU RU2016123855A patent/RU2016123855A/ru unknown
- 2014-11-19 KR KR1020167016033A patent/KR20160078504A/ko not_active Withdrawn
- 2014-11-19 WO PCT/CA2014/000836 patent/WO2015074135A1/en not_active Ceased
- 2014-11-19 EP EP14863267.2A patent/EP3071572A4/en not_active Withdrawn
- 2014-11-19 CN CN201480068293.5A patent/CN105829313A/zh active Pending
- 2014-11-19 JP JP2016531021A patent/JP2016537367A/ja not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016187723A1 (en) * | 2015-05-27 | 2016-12-01 | Pharmascience Inc. | Inhibitors of the tec kinase enzyme family |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016537367A (ja) | 2016-12-01 |
| CA2929881A1 (en) | 2015-05-28 |
| EP3071572A1 (en) | 2016-09-28 |
| CN105829313A (zh) | 2016-08-03 |
| TW201542554A (zh) | 2015-11-16 |
| EP3071572A4 (en) | 2017-04-05 |
| WO2015074135A1 (en) | 2015-05-28 |
| US20160289236A1 (en) | 2016-10-06 |
| RU2016123855A (ru) | 2017-12-25 |
| KR20160078504A (ko) | 2016-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20161121 |