CA2832851C - Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone - Google Patents

Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone Download PDF

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Publication number
CA2832851C
CA2832851C CA2832851A CA2832851A CA2832851C CA 2832851 C CA2832851 C CA 2832851C CA 2832851 A CA2832851 A CA 2832851A CA 2832851 A CA2832851 A CA 2832851A CA 2832851 C CA2832851 C CA 2832851C
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Prior art keywords
paco2
subject
invasive method
increase
coronary
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CA2832851A
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CA2832851A1 (fr
Inventor
Rohan Dharmakumar
Debiao Li
Sotirios A. Tsaftaris
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Cedars Sinai Medical Center
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Cedars Sinai Medical Center
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Priority to CA2832851A priority Critical patent/CA2832851C/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

Il est décrit des méthodes de diagnostic de la maladie coronarienne chez un sujet en ayant besoin. Lesdites méthodes impliquent l'administration d'un mélange comprenant du CO2 à un sujet, ce qui permet d'atteindre une PaCO2 prédéterminée chez le sujet en vue de l'induction d'une hyperémie, cela étant suivi de la surveillance de la réactivité vasculaire chez le sujet et du diagnostic de la présence ou de l'absence de maladie coronarienne chez le sujet. Une moindre réactivité vasculaire chez le sujet par rapport à un sujet témoin marque la présence d'une maladie coronarienne. Il est également décrit des méthodes permettant de renforcer la sensibilité et la spécificité de l'imagerie par résonance magnétique dépendante du niveau d'oxygène dans le sang.
CA2832851A 2013-11-08 2013-11-08 Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone Active CA2832851C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2832851A CA2832851C (fr) 2013-11-08 2013-11-08 Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2832851A CA2832851C (fr) 2013-11-08 2013-11-08 Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone

Publications (2)

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CA2832851A1 CA2832851A1 (fr) 2015-05-08
CA2832851C true CA2832851C (fr) 2023-10-17

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CA2832851A Active CA2832851C (fr) 2013-11-08 2013-11-08 Evaluation de la maladie coronarienne faisant appel au dioxyde de carbone

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11439309B2 (en) 2011-05-05 2022-09-13 Cedars-Sinai Medical Center Assessment of coronary heart disease with carbon dioxide
US11129911B2 (en) 2011-05-05 2021-09-28 Cedars-Sinai Medical Center Assessment of coronary heart disease with carbon dioxide
US10471094B2 (en) 2013-08-05 2019-11-12 Cedars-Sinai Medical Center Methods for reducing ischemia-reperfusion injury via targeted control of blood gases

Also Published As

Publication number Publication date
CA2832851A1 (fr) 2015-05-08

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